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Biological effects of manufactured nanoparticles : influence of their charactéristics

Abstract : Development of nanosciences and nanotechnologies may lead to considerable release of nanoparticles in the environment, potentially toxic for ecosystems and human health. Therefore, nanotoxicology attracts attention of public and governments worldwide. In this work comparative in vitro toxicological assessment, cellular localization and oxidative stress of titanium oxide nanoparticles and carbon nanotubes was carried out on one eukaryotic model, the human pneumocyte II A549 cell line allowing to simulate contact after inhalation, and on two prokaryotic model, Escherichia coli MG1655 and the soil bacterium Cupriavidus metallidurans CH34 allowing to simulate contamination of the environment. Results show biological responses to nanoparticles which depends on models, on exposure
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https://pastel.archives-ouvertes.fr/pastel-00004918
Contributor : Ecole Agroparistech <>
Submitted on : Thursday, March 19, 2009 - 8:00:00 AM
Last modification on : Thursday, March 19, 2009 - 8:00:00 AM
Long-term archiving on: : Thursday, September 30, 2010 - 8:46:18 PM

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  • HAL Id : pastel-00004918, version 1

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Angélique Simon-Deckers. Biological effects of manufactured nanoparticles : influence of their charactéristics. Life Sciences [q-bio]. AgroParisTech, 2008. English. ⟨NNT : 2008AGPT0081⟩. ⟨pastel-00004918⟩

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