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Theses

Traitement d'image appliqué aux images d'autofluorescence dans le cadre de la Dégénérescence Maculaire Liée à l'Âge (DMLA)

Abstract : Age-related Macular Disease (AMD) is the leading cause of blindness in people over the age of 55. In its early stages, the patients may still have no visual impairment. In advanced stages, a wet and a dry form have to be distinguished. The wet form is defined by the growth of new vessels under the retina. The dry form is characterized by atrophies often called geographic atrophies of the photoreceptors and the Retinal Pigment Epithelium. In both forms the central retina may be destroyed by subsequent photoreceptor degeneration with severe vision loss. In recent years, Fundus AutoFluorescence (FAF) imaging has shown to be useful for AMD, especially for dry AMD type with regards to diagnosis, documentation of changes, identification of disease progression, and monitoring of novel therapies. The FAF images of the retina are obtained with an angiograph equipped with a scanning laser of 488 nm wavelength (Scanning Laser Ophthalmoscope (SLO)). The autofluorescence is emitted by the presence of a pigment (lipofuscin), which is a good indicator of the retinal activity. The FAF images are captured with a SLO in a sequence of 15-20 images, each having low signal to noise ratio and low contrast. The objective of the thesis is the development of tools for the automatic processing of FAF images. These tools will help the specialists in the diagnosis and follow up of the disease.
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Theses
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https://pastel.archives-ouvertes.fr/pastel-00005958
Contributor : Ecole Mines Paristech <>
Submitted on : Friday, April 9, 2010 - 8:00:00 AM
Last modification on : Thursday, September 24, 2020 - 4:38:02 PM
Long-term archiving on: : Wednesday, July 28, 2010 - 8:24:35 PM

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  • HAL Id : pastel-00005958, version 1

Citation

Adnan Rashid Chaudhry. Traitement d'image appliqué aux images d'autofluorescence dans le cadre de la Dégénérescence Maculaire Liée à l'Âge (DMLA). Mathématiques [math]. École Nationale Supérieure des Mines de Paris, 2009. Français. ⟨pastel-00005958⟩

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