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Theses

Vers la synthèse du tricycle ABC du Taxol

Abstract : During this thesis, we tried to apply the olefin metathesis reaction to the synthesis of the ABC tricycle of taxol, a natural molecule isolated in the 60' from the pacifican yew. We have studied to different retrosyntheses: - the first relies on relay ring closing metathesis to form the eight-membered B ring. - the second relies on an ene-yne-ene tandem metathesis to form the A and B cycles in one single step.
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Contributor : Rémi Aouzal <>
Submitted on : Wednesday, September 8, 2010 - 6:42:34 PM
Last modification on : Wednesday, January 23, 2019 - 10:29:06 AM
Long-term archiving on: : Thursday, December 9, 2010 - 2:51:59 AM

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Rémi Aouzal. Vers la synthèse du tricycle ABC du Taxol. Chimie organique. Ecole Polytechnique X, 2010. Français. ⟨pastel-00516141⟩

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