Bioorganometallic chemistry???from teaching paradigms to medicinal applications, Chem. Soc. Rev., vol.48, issue.2, pp.391-401, 2009. ,
DOI : 10.1039/B707077M
Development of organometallic (organo-transition metal) pharmaceuticals, Applied Organometallic Chemistry, vol.125, issue.192, pp.1-10, 2005. ,
DOI : 10.1002/aoc.725
Bioorganometallic fulvene-derived titanocene anti-cancer drugs, Chemical Society Reviews, vol.18, issue.644, pp.1174-1187, 2008. ,
DOI : 10.1039/b707310k
Labeling of Biomolecules for Medicinal Applications???Bioorganometallic Chemistry at Its Best, Angewandte Chemie International Edition, vol.21, issue.6, pp.1040-1043, 2001. ,
DOI : 10.1002/1521-3773(20010316)40:6<1040::AID-ANIE10400>3.0.CO;2-P
Synthesis, Biochemical Properties and Molecular Modelling Studies of Organometallic Specific Estrogen Receptor Modulators (SERMs), the Ferrocifens and Hydroxyferrocifens: Evidence for an Antiproliferative Effect of Hydroxyferrocifens on both Hormone-Dependent and Hormone-Independent Breast Cancer Cell Lines, Chemistry - A European Journal, vol.9, issue.21, pp.5223-5236, 2003. ,
DOI : 10.1002/chem.200305024
Enantioselective Synthesis of Ferrocenyl Nucleoside Analogues with Apoptosis-Inducing Activity, Organic Letters, vol.8, issue.13, pp.2763-2766, 2006. ,
DOI : 10.1021/ol060868f
Rational Design of an Organometallic Glutathione Transferase Inhibitor, Angewandte Chemie International Edition, vol.270, issue.21, pp.3854-3857, 2009. ,
DOI : 10.1002/anie.200900185
On the medicinal chemistry of gold complexes as anticancer drugs, Coordination Chemistry Reviews, vol.253, issue.11-12, pp.1670-1681, 2009. ,
DOI : 10.1016/j.ccr.2009.02.019
Antiproliferative Activity of Gold(I) Alkyne Complexes Containing Water-Soluble Phosphane Ligands, Organometallics, vol.29, issue.11, pp.2596-2603, 2010. ,
DOI : 10.1021/om100300a
A New Type of Organo-Iron Compound, Nature, vol.165, issue.4285, pp.1039-1040, 1951. ,
DOI : 10.1038/1681039b0
THE STRUCTURE OF IRON BIS-CYCLOPENTADIENYL, Journal of the American Chemical Society, vol.74, issue.8, pp.2125-2126, 1952. ,
DOI : 10.1021/ja01128a527
Ferrocene: Ironclad History or Rashomon Tale?, Angewandte Chemie International Edition, vol.39, issue.1, pp.123-124, 2000. ,
DOI : 10.1002/(SICI)1521-3773(20000103)39:1<123::AID-ANIE123>3.0.CO;2-Z
Synthesis of 1-ferrocenyl-2-aryl(heteroaryl)acetylenes and 2-ferrocenylindole derivatives via the Sonogashira???Heck???Cassar reaction, Tetrahedron, vol.58, issue.22, pp.4487-4492, 2002. ,
DOI : 10.1016/S0040-4020(02)00394-0
Synthesis of unsymmetrical 1,1???-disubstituted ferrocenes. Formation of ferrocenophanes via intramolecular cycloaddition, Journal of Organometallic Chemistry, vol.654, issue.1-2, pp.117-122, 2002. ,
DOI : 10.1016/S0022-328X(02)01394-3
Ferrocene-Homogeneous Catalysis, Organic Synthesis and Materials Science, 1995. ,
The iron sandwich. A recollection of the first four months, Journal of Organometallic Chemistry, vol.100, issue.1, pp.273-278, 1975. ,
DOI : 10.1016/S0022-328X(00)88947-0
Comprehensive Organometallic Chemistry, 1963. ,
Principle and Application of Organotransition Metal Chemistry, 1980. ,
Ferricenium complexes: A new type of water-soluble antitumor agent, Journal of Cancer Research and Clinical Oncology, vol.12, issue.3, pp.336-340, 1984. ,
DOI : 10.1007/BF00390468
On the mechanism of the antitumor activity of ferrocenium derivatives, Inorganica Chimica Acta, vol.306, issue.1, pp.42-48, 2000. ,
DOI : 10.1016/S0020-1693(00)00147-X
1,1???-Ferrocenyldiacetic Acid Anhydride and its Use in the preparation of heteroannularly substituted ferrocenyl-penicillins and -cephalosporins., Journal of Organometallic Chemistry, vol.122, issue.3, pp.49-53, 1976. ,
DOI : 10.1016/S0022-328X(00)82406-7
Organometallic derivatives of penicillins and cephalosporins a new class of semi-synthetic antibiotics, Journal of Organometallic Chemistry, vol.85, issue.2, pp.23-25, 1975. ,
DOI : 10.1016/S0022-328X(00)80708-1
Bioorganometallic chemistry: a future direction for transition metal organometallic chemistry?, Accounts of Chemical Research, vol.26, issue.7, pp.361-369, 1993. ,
DOI : 10.1021/ar00031a002
Facile route to ferrocifen, 1-[4-(2-dimethylaminoethoxy)]-1-(phenyl-2-ferrocenyl-but-1-ene), first organometallic analogue of tamoxifen, by the McMurry reaction, Journal of Organometallic Chemistry, vol.541, issue.1-2, pp.355-361, 1997. ,
DOI : 10.1016/S0022-328X(97)00086-7
New paradigms for synthetic pathways inspired by bioorganometallic chemistry, Journal of Organometallic Chemistry, vol.600, issue.1-2, pp.23-36, 2000. ,
DOI : 10.1016/S0022-328X(00)00036-X
Bioorganometallic Chemistry:?? Structural Diversity of Organometallic Complexes with Bioligands and Molecular Recognition Studies of Several Supramolecular Hosts with Biomolecules, Alkali-Metal Ions, and Organometallic Pharmaceuticals, Organometallics, vol.22, issue.11, pp.2166-2177, 2003. ,
DOI : 10.1021/om0300777
Synthesis and Antimalarial Activity in Vitro and in Vivo of a New Ferrocene???Chloroquine Analogue, Journal of Medicinal Chemistry, vol.40, issue.23, pp.3715-3718, 1997. ,
DOI : 10.1021/jm970401y
Platinum Compounds: a New Class of Potent Antitumour Agents, Nature, vol.34, issue.5191, pp.385-386, 1969. ,
DOI : 10.1038/222385a0
Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode, Nature, vol.3, issue.4972, pp.698-699, 1965. ,
DOI : 10.1038/205698a0
Modification of the Estrogenic Properties of Diphenols by the Incorporation of Ferrocene. Generation of Antiproliferative Effects in Vitro, Journal of Medicinal Chemistry, vol.48, issue.12, pp.3937-3940, 2005. ,
DOI : 10.1021/jm050251o
Ferrocene-Mediated Proton-Coupled Electron Transfer in a Series of Ferrocifen-Type Breast-Cancer Drug Candidates, Angewandte Chemie International Edition, vol.44, issue.2, pp.285-290, 2006. ,
DOI : 10.1002/anie.200502925
Organometallic cluster analogues of tamoxifen: Synthesis and biochemical assay, Journal of Organometallic Chemistry, vol.691, issue.1-2, pp.9-19, 2006. ,
DOI : 10.1016/j.jorganchem.2005.08.041
Lipid nanocapsules loaded with an organometallic tamoxifen derivative as a novel drug-carrier system for experimental malignant gliomas, Journal of Controlled Release, vol.130, issue.2, pp.146-153, 2008. ,
DOI : 10.1016/j.jconrel.2008.05.027
URL : https://hal.archives-ouvertes.fr/inserm-00343557
Dose effect activity of ferrocifen-loaded lipid nanocapsules on a 9L-glioma model, International Journal of Pharmaceutics, vol.379, issue.2, pp.317-323, 2009. ,
DOI : 10.1016/j.ijpharm.2009.05.031
URL : https://hal.archives-ouvertes.fr/hal-01230396
Synthesis and Structure-Activity Relationships of Ferrocenyl Tamoxifen Derivatives with Modified Side Chains, Chemistry - A European Journal, vol.33, issue.3, pp.684-696, 2009. ,
DOI : 10.1002/chem.200801108
URL : https://hal.archives-ouvertes.fr/hal-00376089
Reactivity and Antiproliferative Activity of Ferrocenyl-Tamoxifen Adducts with Cyclodextrins against Hormone-Independent Breast-Cancer Cell Lines, Chemistry - A European Journal, vol.1, issue.27, pp.8195-8203, 2008. ,
DOI : 10.1002/chem.200800507
Ferrocenyl Quinone Methides as Strong Antiproliferative Agents: Formation by Metabolic and Chemical Oxidation of Ferrocenyl Phenols, Angewandte Chemie International Edition, vol.36, issue.48, pp.9124-9126, 2009. ,
DOI : 10.1002/anie.200903768
Influence of structural changes in ferrocene phosphane aminophosphane ligands on their catalytic activity, Journal of Organometallic Chemistry, vol.694, issue.12, pp.1898-1902, 2009. ,
DOI : 10.1016/j.jorganchem.2009.01.027
Preparation of enantiopure 1,4-amino alcohols derived from [3]ferrocenophanes: use in the asymmetric addition of diethylzinc to benzaldehyde, Tetrahedron: Asymmetry, vol.16, issue.6, pp.1189-1197, 2005. ,
DOI : 10.1016/j.tetasy.2005.01.041
URL : https://hal.archives-ouvertes.fr/hal-00100251
Ferrocene-Derived Bioorganometallic Chemistry: Preparation of a [3]Ferrocenophane ??-Amino Acid for Use in Peptide Synthesis, Organometallics, vol.27, issue.17, pp.4269-4272, 2008. ,
DOI : 10.1021/om8004542
A [3]Ferrocenophane Polyphenol Showing a Remarkable Antiproliferative Activity on Breast and Prostate Cancer Cell Lines, Journal of Medicinal Chemistry, vol.52, issue.15, pp.4964-4967, 2009. ,
DOI : 10.1021/jm900297x
URL : https://hal.archives-ouvertes.fr/hal-00448988
)-4-Hydroxytoremifene via McMurry Reaction, The Journal of Organic Chemistry, vol.61, issue.11, pp.3890-3893, 1996. ,
DOI : 10.1021/jo952279l
Flexible Estrogen Receptor Modulators:?? Design, Synthesis, and Antagonistic Effects in Human MCF-7 Breast Cancer Cells, Journal of Medicinal Chemistry, vol.44, issue.7, pp.1072-1084, 2001. ,
DOI : 10.1021/jm001119l
-Hydroxyphenyl)-2-phenyl]-1butenyl]phenoxyacetic Acid, The Journal of Organic Chemistry, vol.67, issue.13, pp.4608-4611, 2002. ,
DOI : 10.1021/jo0255328
)-4-Hydroxytamoxifen, a Potent Estrogen Receptor Modulator, The Journal of Organic Chemistry, vol.68, issue.24, pp.9489-9491, 2003. ,
DOI : 10.1021/jo035164n
Synthesis, Biochemical Properties and Molecular Modelling Studies of Organometallic Specific Estrogen Receptor Modulators (SERMs), the Ferrocifens and Hydroxyferrocifens: Evidence for an Antiproliferative Effect of Hydroxyferrocifens on both Hormone-Dependent and Hormone-Independent Breast Cancer Cell Lines, Chemistry - A European Journal, vol.9, issue.21, pp.5223-5236, 2003. ,
DOI : 10.1002/chem.200305024
New method for the reductive coupling of carbonyls to olefins. Synthesis of .beta.-carotene, Journal of the American Chemical Society, vol.96, issue.14, pp.4708-4709, 1974. ,
DOI : 10.1021/ja00821a076
Carbonyl-coupling reactions using low-valent titanium, Chemical Reviews, vol.89, issue.7, pp.1513-1524, 1989. ,
DOI : 10.1021/cr00097a007
Wolochow.I Bulletin De La Societe Chimique De France Partie Ii-Chimie Moleculaire Organique Et Biologique, pp.2147-2148, 1973. ,
McMurry coupling of aryl aldehydes and imino pinacol coupling mediated by Ti(O-i-Pr)4/Me3SiCl/Mg reagent, Tetrahedron Letters, vol.51, issue.2, pp.387-390, 2010. ,
DOI : 10.1016/j.tetlet.2009.11.027
Synthesis of a conformationally restricted polyoxygenated crownophane, Tetrahedron Letters, vol.46, issue.41, pp.7055-7057, 2005. ,
DOI : 10.1016/j.tetlet.2005.08.036
McMurry reactions of (??5-acetylcyclopentadienyl) cobalt-(??4-tetraphenylcyclobutadiene) with benzophenone: ketone couplings and a pinacol/pinacolone rearrangement, Journal of Organometallic Chemistry, vol.689, issue.25, pp.4683-4690, 2004. ,
DOI : 10.1016/j.jorganchem.2004.07.015
"Site Selective" Formation of Low-Valent Titanium Reagents: An "Instant" Procedure for the Reductive Coupling of Oxo Amides to Indoles, The Journal of Organic Chemistry, vol.59, issue.18, pp.5215-5229, 1994. ,
DOI : 10.1021/jo00097a024
Convenient One-Pot Synthesis of 2,2-Bis-(4-hydroxyphenyl)-cyclopentanone, The Journal of Organic Chemistry, vol.73, issue.2, pp.715-718, 2008. ,
DOI : 10.1021/jo701850u
Influence of External Ligands and Auxiliaries on the Reactivity of Low-Valent Titanium in McMurry Reaction:?? Selectivity and Mechanistic Profile, Journal of the American Chemical Society, vol.118, issue.25, pp.5932-5937, 1996. ,
DOI : 10.1021/ja9535221
The replacement of a phenol group by an aniline or acetanilide group enhances the cytotoxicity of 2-ferrocenyl-1,1-diphenyl-but-l-ene compounds against breast cancer cells, Journal of Organometallic Chemistry, vol.694, issue.6, pp.895-901, 2009. ,
DOI : 10.1016/j.jorganchem.2008.11.035
A [3]Ferrocenophane Polyphenol Showing a Remarkable Antiproliferative Activity on Breast and Prostate Cancer Cell Lines, Journal of Medicinal Chemistry, vol.52, issue.15, pp.4964-4967, 2009. ,
DOI : 10.1021/jm900297x
URL : https://hal.archives-ouvertes.fr/hal-00448988
Organometallic analogues of tamoxifen: Effect of the amino side-chain replacement by a carbonyl ferrocenyl moiety in hydroxytamoxifen, Journal of Organometallic Chemistry, vol.692, issue.6, pp.1219-1225, 2007. ,
DOI : 10.1016/j.jorganchem.2006.11.016
URL : https://hal.archives-ouvertes.fr/hal-01230401
Organometallic diphenols: The importance of the organometallic moiety on the expression of a cytotoxic effect on breast cancer cells, Journal of Organometallic Chemistry, vol.692, issue.6, pp.1315-1326, 2007. ,
DOI : 10.1016/j.jorganchem.2006.10.041
URL : https://hal.archives-ouvertes.fr/hal-01230402
Modification of the Estrogenic Properties of Diphenols by the Incorporation of Ferrocene. Generation of Antiproliferative Effects in Vitro, Journal of Medicinal Chemistry, vol.48, issue.12, pp.3937-3940, 2005. ,
DOI : 10.1021/jm050251o
Synthesis, Biochemical Properties and Molecular Modelling Studies of Organometallic Specific Estrogen Receptor Modulators (SERMs), the Ferrocifens and Hydroxyferrocifens: Evidence for an Antiproliferative Effect of Hydroxyferrocifens on both Hormone-Dependent and Hormone-Independent Breast Cancer Cell Lines, Chemistry - A European Journal, vol.9, issue.21, pp.5223-5236, 2003. ,
DOI : 10.1002/chem.200305024
Ferrocene-Mediated Proton-Coupled Electron Transfer in a Series of Ferrocifen-Type Breast-Cancer Drug Candidates, Angewandte Chemie International Edition, vol.44, issue.2, pp.285-290, 2006. ,
DOI : 10.1002/anie.200502925
Ferrocenyl Quinone Methides as Strong Antiproliferative Agents: Formation by Metabolic and Chemical Oxidation of Ferrocenyl Phenols, Angewandte Chemie International Edition, vol.36, issue.48, pp.9124-9126, 2009. ,
DOI : 10.1002/anie.200903768
Ansa-Metallocenes by Intramolecular Ring Closure Reactions ??? Syntheses and Applications, Macromolecular Symposia, vol.84, issue.639, pp.1-13, 2006. ,
DOI : 10.1002/masy.200690041
Application of Biginelli reaction to the synthesis of ferrocenylpyrimidones and [3]-ferrocenophane-containing pyrimido[4,5-d]pyrimidinediones, Journal of Organometallic Chemistry, vol.694, issue.22, pp.3667-3673, 2009. ,
DOI : 10.1016/j.jorganchem.2009.06.017
Synthesis, computational modelling and liquid crystalline properties of some [3]ferrocenophane-containing Schiff???s bases and ??-aminovinylketone: Molecular geometry???phase behaviour relationship, Journal of Organometallic Chemistry, vol.692, issue.25, pp.5571-5582, 2007. ,
DOI : 10.1016/j.jorganchem.2007.09.010
Developing some functional group chemistry at the Group 4 bent metallocene frameworks, Journal of Organometallic Chemistry, vol.689, issue.8, pp.1402-1412, 2004. ,
DOI : 10.1016/j.jorganchem.2003.12.027
Influence of structural changes in ferrocene phosphane aminophosphane ligands on their catalytic activity, Journal of Organometallic Chemistry, vol.694, issue.12, pp.1898-1902, 2009. ,
DOI : 10.1016/j.jorganchem.2009.01.027
Ferrocene-Derived Bioorganometallic Chemistry: Preparation of a [3]Ferrocenophane ??-Amino Acid for Use in Peptide Synthesis, Organometallics, vol.27, issue.17, pp.4269-4272, 2008. ,
DOI : 10.1021/om8004542
Facile route to ferrocifen, 1-[4-(2-dimethylaminoethoxy)]-1-(phenyl-2-ferrocenyl-but-1-ene), first organometallic analogue of tamoxifen, by the McMurry reaction, Journal of Organometallic Chemistry, vol.541, issue.1-2, pp.355-361, 1997. ,
DOI : 10.1016/S0022-328X(97)00086-7
Selective Estrogen Receptor Modulators in the Ruthenocene Series. Synthesis and Biological Behavior, Journal of Medicinal Chemistry, vol.48, issue.8, pp.2814-2821, 2005. ,
DOI : 10.1021/jm049268h
URL : https://hal.archives-ouvertes.fr/hal-00093015
Bridged ferrocenes, Journal of Organometallic Chemistry, vol.46, issue.1, pp.109-117, 1972. ,
DOI : 10.1016/S0022-328X(00)90481-9
Insights into the General and Efficient Cross McMurry Reactions between Ketones, The Journal of Organic Chemistry, vol.71, issue.26, pp.9873-9876, 2006. ,
DOI : 10.1021/jo061644d
Carbonyl-coupling reactions using low-valent titanium, Chemical Reviews, vol.89, issue.7, pp.1513-1524, 1989. ,
DOI : 10.1021/cr00097a007
Synthesis and receptor-binding affinity of fluorotamoxifen, a possible estrogen-receptor imaging agent, Journal of Medicinal Chemistry, vol.28, issue.10, pp.1504-1511, 1985. ,
DOI : 10.1021/jm00148a022
Synthesis and Structure???Activity Studies of Novel Orally Active Non-Terpenoic 2,3-Oxidosqualene Cyclase Inhibitors, Journal of Medicinal Chemistry, vol.46, issue.15, pp.3354-3370, 2003. ,
DOI : 10.1021/jm021120f
Tamoxifen, Drugs, vol.37, issue.4, pp.451-490, 1989. ,
DOI : 10.2165/00003495-198937040-00004
Overview of the impact of conventional systemic therapies on breast cancer, Endocrine Related Cancer, vol.12, issue.Supplement_1, pp.9-16, 2005. ,
DOI : 10.1677/erc.1.01003
Modification of the Estrogenic Properties of Diphenols by the Incorporation of Ferrocene. Generation of Antiproliferative Effects in Vitro, Journal of Medicinal Chemistry, vol.48, issue.12, pp.3937-3940, 2005. ,
DOI : 10.1021/jm050251o
A [3]Ferrocenophane Polyphenol Showing a Remarkable Antiproliferative Activity on Breast and Prostate Cancer Cell Lines, Journal of Medicinal Chemistry, vol.52, issue.15, pp.4964-4967, 2009. ,
DOI : 10.1021/jm900297x
URL : https://hal.archives-ouvertes.fr/hal-00448988
Organometallic SERMs (selective estrogen receptor modulators): Cobaltifens, the (cyclobutadiene)cobalt analogues of hydroxytamoxifen, Journal of Organometallic Chemistry, vol.695, issue.4, pp.595-608, 2010. ,
DOI : 10.1016/j.jorganchem.2009.11.003
Organometallic analogues of tamoxifen: Effect of the amino side-chain replacement by a carbonyl ferrocenyl moiety in hydroxytamoxifen, Journal of Organometallic Chemistry, vol.692, issue.6, pp.1219-1225, 2007. ,
DOI : 10.1016/j.jorganchem.2006.11.016
URL : https://hal.archives-ouvertes.fr/hal-01230401
Synthesis, Biochemical Properties and Molecular Modelling Studies of Organometallic Specific Estrogen Receptor Modulators (SERMs), the Ferrocifens and Hydroxyferrocifens: Evidence for an Antiproliferative Effect of Hydroxyferrocifens on both Hormone-Dependent and Hormone-Independent Breast Cancer Cell Lines, Chemistry - A European Journal, vol.9, issue.21, pp.5223-5236, 2003. ,
DOI : 10.1002/chem.200305024
11?? -Chloromethyl-[3H]estradiol-17??: A very high affinity, reversible ligand for the estrogen receptor, Journal of Steroid Biochemistry, vol.28, issue.4, pp.361-370, 1987. ,
DOI : 10.1016/0022-4731(87)91052-1
16.beta.-([18F]Fluoro)estrogens: systematic investigation of a new series of fluorine-18-labeled estrogens as potential imaging agents for estrogen-receptor-positive breast tumors, Journal of Medicinal Chemistry, vol.36, issue.11, pp.1619-1629, 1993. ,
DOI : 10.1021/jm00063a012
Rhenium Carbonyl Complexes of .beta.-Estradiol Derivatives with High Affinity for the Estradiol Receptor: An Approach to Selective Organometallic Radiopharmaceuticals, Journal of the American Chemical Society, vol.117, issue.32, pp.8372-8380, 1995. ,
DOI : 10.1021/ja00137a010
Synthesis and Biological Evaluation of SERMs with Potent Nongenomic Estrogenic Activity, ChemMedChem, vol.292, issue.5, pp.565-571, 2006. ,
DOI : 10.1002/cmdc.200500098
Biological and Biophysical Properties of the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Are Affected by the Presence of Short Alkyl Groups on the Phenyl Ring, Journal of Medicinal Chemistry, vol.53, issue.5, pp.1937-1950, 2010. ,
DOI : 10.1021/jm901561u
URL : https://hal.archives-ouvertes.fr/hal-00462114
Cancer Inst, pp.1552-1558, 1998. ,
Phase II clinical study of toremifene in patients with metastatic breast cancer. Preliminary communication, Journal of Steroid Biochemistry, vol.36, issue.3, pp.235-236, 1990. ,
DOI : 10.1016/0022-4731(90)90014-J
Phase III Randomized Trial of Toremifene vs Tamoxifen in Hormonodependant Advanced Breast Cancer, Breast Cancer Research and Treatment, vol.76, issue.1, pp.119-124, 2001. ,
DOI : 10.1023/A:1006440802709
Toremifene Increases Bone Mineral Density in Men Receiving Androgen Deprivation Therapy for Prostate Cancer: Interim Analysis of a Multicenter Phase 3 Clinical Study, The Journal of Urology, vol.179, issue.1, pp.152-155, 2008. ,
DOI : 10.1016/j.juro.2007.08.137
Organometallic diphenols: The importance of the organometallic moiety on the expression of a cytotoxic effect on breast cancer cells, Journal of Organometallic Chemistry, vol.692, issue.6, pp.1315-1326, 2007. ,
DOI : 10.1016/j.jorganchem.2006.10.041
URL : https://hal.archives-ouvertes.fr/hal-01230402
Anisotropic thermal parameters for C26H22FeO2, p.22 ,