.. Production-et-purification-de-protéines-hétérologues and M. La, 64 B.5.1. Conditions de culture et de production de protéines de fusion avec, ., p.64

.. Etude-de-la-malate-déshydrogénase-(-mdh-)-chez-yarrowia-lipolytica and Y. Cerevisiae, 79 B.1.1. Analyse in silico des gènes de malate déshydrogénases, p.84

M. Localisation-de-la-malate-déshydrogénase-des-mutants, M. Ha, and Y. , 97 B.1.3.1. Stratégie de construction des mutants de fusion, p.99

M. De, I. , and C. , 101 B.2.2. Construction des vecteurs de disruption des gènes 102 B.2.3. Constructions des mutants : transformations de Yarrowia lipolytica, Etude des mutants du cycle du glyoxylate, p.106

Y. La-malate-déshydrogénase-et-les-gènes-du-cycle-du-glyoxylate-chez, 111 B.1. Etude de la malate déshydrogénase (MDH) chez Yarrowia lipolytica 111 B.1.1. Rappel sur les enzymes malate déshydrogénase, ., p.112

A. R. Adham, B. K. Zolman, A. Millius, and B. Bartel, Mutations in Arabidopsis acyl-CoA oxidase genes reveal distinct and overlapping roles in ??-oxidation, The Plant Journal, vol.127, issue.6, pp.859-874, 2005.
DOI : 10.1111/j.1365-313X.2005.02343.x

J. D. Aitchison, W. W. Murray, and R. A. Rachubinski, The Carboxyl-terminal Tripeptide Ala-Lys-Ile Is Essential for Targeting Candida tropicalis Trifunctional Enzyme to Yeast Peroxisomes, J. Biol.Chem, vol.266, pp.23197-23203, 1991.

K. Athenstaedt and G. Daum, Biosynthesis of phosphatidic acid in lipid particles and endoplasmic reticulum of Saccharomyces cerevisiae., Journal of Bacteriology, vol.179, issue.24, pp.7611-7617, 1997.
DOI : 10.1128/jb.179.24.7611-7616.1997

K. Athenstaedt and G. Daum, Phosphatidic acid , a key intermediate in lipid metabolism, European Journal of Biochemistry, vol.180, issue.1, pp.1-16, 1999.
DOI : 10.1016/0005-2760(87)90090-7

K. Athenstaedt and G. Daum, Tgl4p and Tgl5p, Two Triacylglycerol Lipases of the Yeast Saccharomyces cerevisiae Are Localized to Lipid Particles, Journal of Biological Chemistry, vol.280, issue.45, pp.37301-37309, 2005.
DOI : 10.1074/jbc.M507261200

K. D. Atkinson, B. Jensen, A. I. Kolat, E. M. Stmn, S. A. Henry et al., Yeast mutants auxotrophic for choline or ethanolamine, J Bacteriol, vol.141, pp.558-64, 1980.

L. J. Banaszak and I. A. Bradshaw, Malate dehydrogenases In The enzymes, pp.369-396, 1975.

L. D. Barnes, G. D. Kuehn, and D. E. Atkinson, Yeast diphosphopyridine nucleotide specific isocitrate dehydrogenase. Purification and some properties, Biochemistry, vol.10, issue.21, pp.3939-3983, 1971.
DOI : 10.1021/bi00797a022

G. Barth and H. Weber, Genetic studies on the yeast Saccharomycopsis lipolytica Inactivation and mutagenesis, Zeitschrift f??r allgemeine Mikrobiologie, vol.109, issue.3, pp.147-57, 1983.
DOI : 10.1002/jobm.19830230302

G. Barth, J. M. Beckerich, A. Dominguez, S. Kerscher, D. Ogrydziak et al., Functional genetics of Yarrowia lipolytica, Functional Genetics of industrial yeasts, pp.227-271, 2003.
DOI : 10.1007/3-540-37003-X_8

G. Barth and T. Scheuber, Cloning of the isocitrate lyase gene (ICL1) from Yarrowia lipolytica and characterization of the deduced protein, MGG Molecular & General Genetics, vol.241, issue.3-4, pp.422-452, 1993.
DOI : 10.1007/BF00284696

J. Bassel and R. Mortimer, Genetic analysis of mating type and alkane utilization in Saccharomycopsis lipolytica, J Bacteriol, vol.114, pp.894-900, 1973.

J. Bassel, J. Warfel, and R. Mortimer, Complementation and genetic recombination in Candida lipolytica, J Bacteriol, vol.108, pp.609-620, 1971.

J. M. Beckerich, M. Lambert, and C. Gaillardin, LYC1 is the structural gene for lysine N-6-acetyl transferase in yeast, Current Genetics, vol.16, issue.1, pp.24-33, 1994.
DOI : 10.1007/BF00712962

A. Beopoulos, Z. Mrozova, F. Thevenieau, L. Dall, M. T. Hapala et al., Control of Lipid Accumulation in the Yeast Yarrowia lipolytica, Applied and Environmental Microbiology, vol.74, issue.24, pp.7779-89, 2008.
DOI : 10.1128/AEM.01412-08

G. Berninger, R. Schmidtchen, G. Casel, A. Knörr, K. Rautenstrauss et al., Structure and metabolic control of the Yarrowia lipolytica peroxisomal 3-oxoacyl-CoA-thiolase gene, European Journal of Biochemistry, vol.11, issue.2, pp.607-620, 1993.
DOI : 10.1016/0968-0004(86)90007-1

J. J. Birktoft and L. J. Banaszak, The presence of ahistidine-aspartic acid pair in the active site of 2-hydroxyacid dehydrogenases. X-ray refinement of cytoplasmic malate dehydrogenase, J. Biol. Chem, vol.258, pp.472-482, 1983.

J. J. Birktoft, R. T. Fernley, R. A. Bradshaw, and L. J. Banaszak, Amino acid sequence homology among the 2-hydroxy acid dehydrogenases: mitochondrial and cytoplasmic malate dehydrogenases form a homologous system with lactate dehydrogenase., Proceedings of the National Academy of Sciences, vol.79, issue.20, 1982.
DOI : 10.1073/pnas.79.20.6166

E. Bon, S. Casaregola, G. Blandin, B. Llorente, C. Neuveglise et al., Molecular evolution of eukaryotic genomes: hemiascomycetous yeast spliceosomal introns, Nucleic Acids Research, vol.31, issue.4, pp.1121-1135, 2003.
DOI : 10.1093/nar/gkg213
URL : https://hal.archives-ouvertes.fr/inria-00339881

L. A. Brown and A. Baker, Shuttles and cycles: transport of proteins into the peroxisome matrix (Review), Molecular Membrane Biology, vol.142, issue.5, pp.363-75, 2008.
DOI : 10.4161/auto.3534

G. M. Carman, Phosphatidate phosphatases and diacylglycerol pyrophosphate phosphatases in Saccharomyces cerevisiae and Escherichia coli, Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol.1348, issue.1-2, pp.45-55, 1997.
DOI : 10.1016/S0005-2760(97)00095-7

G. M. Carman and G. S. Han, Roles of phosphatidate phosphatase enzymes in lipid metabolism, Trends in Biochemical Sciences, vol.31, issue.12, pp.694-703, 2006.
DOI : 10.1016/j.tibs.2006.10.003

G. M. Carman and S. A. Henry, Phospholipid biosynthesis in the yeast Saccharomyces cerevisiae and interrelationship with other metabolic processes, Progress in Lipid Research, vol.38, issue.5-6, pp.361-99, 1999.
DOI : 10.1016/S0163-7827(99)00010-7

G. M. Carman and S. A. Henry, Phosphatidic Acid Plays a Central Role in the Transcriptional Regulation of Glycerophospholipid Synthesis in Saccharomyces cerevisiae, Journal of Biological Chemistry, vol.282, issue.52, pp.37293-37300, 2007.
DOI : 10.1074/jbc.R700038200

G. Carman, M. Zeimetz, and G. M. , Regulation of Phospholipid Biosynthesis in the Yeast Saccharomyces cerevisiae, Journal of Biological Chemistry, vol.271, issue.23, pp.13293-13296, 1996.
DOI : 10.1074/jbc.271.23.13293

S. Casaregola, C. Neuvéglise, E. Bon, and C. Gaillardin, Ylli, a Non-LTR Retrotransposon L1 Family in the Dimorphic Yeast Yarrowia lipolytica, Molecular Biology and Evolution, vol.19, issue.5, pp.664-677, 2002.
DOI : 10.1093/oxfordjournals.molbev.a004125

S. Casaregola, C. Neuvéglise, A. Lépingle, E. Bon, C. Feynerol et al., Genomic exploration of hemiascomycetous yeasts, p.17, 2000.
URL : https://hal.archives-ouvertes.fr/hal-00115674

S. Cases, S. J. Smith, H. M. Zheng, S. R. Myers, E. Lear et al., Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis, Proc. Natl. Acad. Sci. USA 95, pp.13018-13023, 1998.
DOI : 10.1073/pnas.95.22.13018

C. C. Chang, H. Y. Huh, K. M. Cadigan, and T. Y. Chang, Molecular cloning and functional expression of human acyl coenzyme A:cholesterol acyltransferase cDNA in mutant Chinese Hamster Ovary cells, J. Biol.Chem, vol.268, pp.20747-20755, 1993.

Y. F. Chang and G. M. Carman, CTP synthetase and its role in phospholipid synthesis in the yeast Saccharomyces cerevisiae, Progress in Lipid Research, vol.47, issue.5, pp.333-342, 2008.
DOI : 10.1016/j.plipres.2008.03.004

K. Christiansen, Triacylglycerol synthesis in lipid particles from baker's yeast (Saccharomyces cerevisiae), Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol.530, issue.1, pp.78-90, 1978.
DOI : 10.1016/0005-2760(78)90128-5

M. J. Conder, Y. Ko, and B. A. Mcfadden, Purification of isocitrate lyase from Escherichia coli and watermelon using fast protein liquid chromatography, Prep biochemistry, pp.431-442, 1988.

T. G. Cooper, The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, pp.39-99, 1982.

C. M. Cruz, C. Martinez, A. Buchala, J. P. Metraux, and J. Leon, Gene-specific involvement of b-oxidation in wound-activated responses in Arabidopsis, Plant Physiol, vol.135, pp.85-94, 2004.

Z. Cui and M. Houweling, Phosphatidylcholine and cell death, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1585, issue.2-3, pp.87-96, 2002.
DOI : 10.1016/S1388-1981(02)00328-1

J. R. Cupp and L. Alister-henn, Cloning and characterization of the gene encoding the IDH1 subunit of NAD(+)-dependent isocitrate dehydrogenase from Saccharomyces cerevisiae, J Biol Chem, vol.267, pp.16417-16440, 1992.

T. Czabany, K. Athenstaedt, and G. Daum, Synthesis, storage and degradation of neutral lipids in yeast, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1771, issue.3, pp.299-309, 2006.
DOI : 10.1016/j.bbalip.2006.07.001

H. Czarnecka and S. Yokoyama, Regulation of lecithin-cholesterol acyltransferase reaction by acyl acceptors and demonstration of its "idling" reaction, J Biol Chem, vol.268, pp.19334-19374, 1993.

A. Dahlqvist, U. Stahl, M. Lenman, A. Banas, M. Lee et al., Phospholipid: diacylglycerol acyltransferase: an enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants, Proc. Natl. Acad. Sci. USA, pp.6487-6492, 2000.

A. Datta, J. M. Merz, and H. Spivey, Substrate channeling of oxalacetate in solidstate complexes of malate dehydrogenase and citrate synthase, J. Biol. Chem, vol.260, 1985.

G. Daum, A. Wagner, T. Czabany, and K. Athenstaedt, Dynamics of neutral lipid storage and mobilization in yeast, Biochimie, vol.89, issue.2, pp.243-251, 2006.
DOI : 10.1016/j.biochi.2006.06.018

G. Daum, Lipids of mitochondria, Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, vol.822, issue.1, pp.1-42, 1985.
DOI : 10.1016/0304-4157(85)90002-4

G. Daum, G. Tuller, T. Nemec, C. Hrastnik, G. Balliano et al., Systematic analysis of yeast strains with possible defects in lipid metabolism, Yeast, vol.11, issue.7, pp.601-614, 1999.
DOI : 10.1002/(SICI)1097-0061(199905)15:7<601::AID-YEA390>3.0.CO;2-N

L. Davidow, O. Donnell, M. Kaczmarek, F. Pereira, D. Dezeeuw et al., Cloning and sequencing of the alkaline extracellular protease gene of Yarrowia lipolytica., Journal of Bacteriology, vol.169, issue.10, pp.4621-4630, 1987.
DOI : 10.1128/jb.169.10.4621-4629.1987

J. M. Delaissé, P. Martin, M. F. Verheyen-bouvy, and E. J. Nyns, Subcellular distribution of enzymes in the yeast Saccharomycopsis lipolytica, grown on n-hexadecane, with special reference to the ??-hydroxylase, Biochimica et Biophysica Acta (BBA) - General Subjects, vol.676, issue.1, pp.77-90, 1981.
DOI : 10.1016/0304-4165(81)90011-8

E. A. Dennis, K. , and E. P. , Intracellular sites of lipid synthesis and the biogenesis of mitochondria, J. Lipid Res, vol.13, pp.263-267, 1972.

L. Dircks and H. S. Sul, Acyltransferases of de novo glycerophospholipid biosynthesis, Progress in Lipid Research, vol.38, issue.5-6, pp.461-79, 1999.
DOI : 10.1016/S0163-7827(99)00012-0

L. K. Dircks and H. S. Sul, Mammalian mitochondrial glycerol-3-phosphate acyltransferase, Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol.1348, issue.1-2, pp.17-26, 1997.
DOI : 10.1016/S0005-2760(97)00106-9

J. Donkor, M. Sariahmetoglu, J. Dewald, D. N. Brindley, and K. Reue, Three Mammalian Lipins Act as Phosphatidate Phosphatases with Distinct Tissue Expression Patterns, Journal of Biological Chemistry, vol.282, issue.6, pp.3450-3457, 2007.
DOI : 10.1074/jbc.M610745200

B. Dujon, D. Sherman, G. Fischer, P. Durrens, S. Casaregola et al., Genome evolution in yeasts, Nature, vol.316, issue.6995, pp.35-44, 2004.
DOI : 10.1093/nar/gkg056
URL : https://hal.archives-ouvertes.fr/hal-00104411

W. Duntze, D. Neumann, J. M. Gancedo, W. Atzpodien, and H. Holzer, Studies on the Regulation and Localization of the Glyoxylate Cycle Enzymes in Saccharomyces cerevisiae, European Journal of Biochemistry, vol.27, issue.1, pp.83-92, 1969.
DOI : 10.1111/j.1432-1033.1969.tb00658.x

J. P. Eastmond, SUGAR-DEPENDENT1 Encodes a Patatin Domain Triacylglycerol Lipase That Initiates Storage Oil Breakdown in Germinating Arabidopsis Seeds, THE PLANT CELL ONLINE, vol.18, issue.3, pp.665-675, 2006.
DOI : 10.1105/tpc.105.040543

P. J. Eastmond, M. Hooks, and I. A. Graham, acyl-CoA oxidase gene family, Biochemical Society Transactions, vol.28, issue.6, pp.755-757, 2000.
DOI : 10.1042/bst0280755

S. A. Ensign, Revisiting the glyoxylate cycle: alternate pathways for microbial acetate assimilation, Molecular Microbiology, vol.21, issue.2, pp.274-280, 2006.
DOI : 10.1128/JB.187.4.1415-1425.2005

R. Erdmann, F. F. Wiebel, A. Flessau, J. Rytka, A. Beyer et al., PAS1, a yeast gene required for peroxisome biogenesis, encodes a member of a novel family of putative ATPases, Cell, vol.64, issue.3, pp.499-510, 1991.
DOI : 10.1016/0092-8674(91)90234-P

J. H. Exton, Phosphatidylcholine breakdown and signal transduction, Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol.1212, issue.1, pp.26-42, 1994.
DOI : 10.1016/0005-2760(94)90186-4

E. Fernandez, F. Moreno, and R. Rodicio, The ICL1 gene from Saccharomyces cerevisiae, European Journal of Biochemistry, vol.72, issue.3, pp.983-90, 1992.
DOI : 10.1083/jcb.108.5.1657

E. Fernandez, F. Moreno, and R. Rodicio, The ICL1 gene from Saccharomyces cerevisiae, European Journal of Biochemistry, vol.72, issue.3, pp.983-90, 1992.
DOI : 10.1083/jcb.108.5.1657

P. Fickers, F. Fudalej, J. Nicaud, J. Destain, and P. Thonart, Selection of new over-producing derivatives for the improvement of extracellular lipase production by the non-conventional yeast Yarrowia lipolytica, Journal of Biotechnology, vol.115, issue.4, pp.379-86, 2005.
DOI : 10.1016/j.jbiotec.2004.09.014

P. Fickers, P. Benetti, Y. Waché, A. Marty, S. Mauersberger et al., Hydrophobic substrate utilisation by the yeast , and its potential applications, FEMS Yeast Research, vol.5, issue.6-7, pp.527-543, 2005.
DOI : 10.1016/j.femsyr.2004.09.004
URL : https://hal.archives-ouvertes.fr/hal-00368201

D. G. Fraenkel, The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, pp.1-37, 1982.

P. Freestone, S. Grant, I. Toth, and V. Norris, Identification of phosphoproteins in Escherichia coli, Molecular Microbiology, vol.174, issue.3, pp.573-580, 1995.
DOI : 10.1016/0968-0004(84)90320-7

Y. Fujiki, Peroxisome biogenesis and peroxisome biogenesis disorders, FEBS Letters, vol.17, issue.1-2, pp.42-46, 2000.
DOI : 10.1016/S0014-5793(00)01667-7

C. Gaillardin and H. Heslot, Genetic engineering inYarrowia lipolytica, Journal of Basic Microbiology, vol.28, issue.3, pp.161-174, 1988.
DOI : 10.1002/jobm.3620280303

C. M. Gaillardin, L. Poirier, A. M. Ribet, and H. Heslot, General and lysine specific control of saccharopine dehydrogenase levels in the yeast Saccharomycopsis lipolytica, Biochimie, vol.61, issue.4, pp.473-82, 1979.
DOI : 10.1016/S0300-9084(79)80203-5

C. Gaillardin, P. Fournier, G. Sylvestre, and H. Heslot, Mutants of Saccharomycopsis lipolytica defective in lysine catabolism, J Bacteriol, vol.125, pp.48-57, 1976.

A. Gangar, A. Karande, and R. And-rajasekharan, Isolation and Localization of a Cytosolic 10 S Triacylglycerol Biosynthetic Multienzyme Complex from Oleaginous Yeast, Journal of Biological Chemistry, vol.276, issue.13, 2001.
DOI : 10.1074/jbc.M009550200

S. P. Gangloff, D. Marguet, and G. J. Lauquin, Molecular cloning of the yeast mitochondrial aconitase gene (ACO1) and evidence of a synergistic regulation of expression by glucose plus glutamate., Molecular and Cellular Biology, vol.10, issue.7, pp.3551-61, 1990.
DOI : 10.1128/MCB.10.7.3551

P. R. Gardner, Superoxide-driven aconitase FE-S center cycling, Bioscience Reports, vol.17, issue.1, pp.33-42, 1997.
DOI : 10.1023/A:1027383100936

S. Ghisla and C. Thorpe, Acyl-CoA dehydrogenases. A mechanistic overview, European Journal of Biochemistry, vol.131, issue.3, 2004.
DOI : 10.1021/bi000123w

N. Gibson and L. Mcalister-henn, Physical and Genetic Interactions of Cytosolic Malate Dehydrogenase with Other Gluconeogenic Enzymes, Journal of Biological Chemistry, vol.278, issue.28, pp.25628-25664, 2003.
DOI : 10.1074/jbc.M213231200

J. Glover, D. Andrews, S. Subramani, and R. Rachubinski, Mutagenesis of the amino targeting signal of Saccharomyces cerevisiae 3-ketoacyl-CoA thiolase reveals conserved amino acids required for import into peroxisomes in vivo, J Biol Chem, vol.269, pp.7558-63, 1994.

S. J. Gould, G. A. Keller, N. Hosken, J. Wilkinson, and S. Subramani, A conserved tripeptide sorts proteins to peroxisomes, The Journal of Cell Biology, vol.108, issue.5, pp.1657-64, 1990.
DOI : 10.1083/jcb.108.5.1657

E. R. Graybill, M. F. Rouhier, C. E. Kirby, and J. W. Hawes, Functional comparison of citrate synthase isoforms from S. cerevisiae, Archives of Biochemistry and Biophysics, vol.465, issue.1, pp.26-37, 2007.
DOI : 10.1016/j.abb.2007.04.039

S. Grönke, A. Mildner, S. Fellert, N. Tennagels, S. Petry et al., Brummer lipase is an evolutionary conservedfat storage regulator in Drosophila, Cell Metab, pp.323-330, 2005.

G. S. Han, S. Siniossoglou, and G. M. Carman, The Cellular Functions of the Yeast Lipin Homolog Pah1p Are Dependent on Its Phosphatidate Phosphatase Activity, Journal of Biological Chemistry, vol.282, issue.51, pp.37026-37061, 2007.
DOI : 10.1074/jbc.M705777200

G. S. Han, W. I. Wu, and G. M. Carman, The Saccharomyces cerevisiae Lipin Homolog Is a Mg2+-dependent Phosphatidate Phosphatase Enzyme, Journal of Biological Chemistry, vol.281, issue.14, pp.9210-9218, 2006.
DOI : 10.1074/jbc.M600425200

G. Han, W. Wu, and G. M. Carman, The Saccharomyces cerevisiae Lipin Homolog Is a Mg2+-dependent Phosphatidate Phosphatase Enzyme, Journal of Biological Chemistry, vol.281, issue.14, pp.9210-9218, 2006.
DOI : 10.1074/jbc.M600425200

R. J. Haselbeck and L. Mcalister-henn, Isolation, nucleotide sequence, and disruption of the Saccharomyces cerevisiae gene encoding mitochondrial NADP(H)-specific isocitrate dehydrogenase, J Biol Chem, vol.266, pp.2339-2384, 1991.

B. Henke, W. Girzalsky, V. Berteaux-lecellier, and R. Erdmann, IDP3 Encodes a Peroxisomal NADP-dependent Isocitrate Dehydrogenase Required for the beta -Oxidation of Unsaturated Fatty Acids, Journal of Biological Chemistry, vol.273, issue.6, pp.3702-3713, 1998.
DOI : 10.1074/jbc.273.6.3702

D. H. Hobbs, C. Lu, and M. J. Hills, and its functional expression, FEBS Letters, vol.157, issue.3, pp.145-149, 1999.
DOI : 10.1016/S0014-5793(99)00646-8

S. Jain, N. Stanford, N. Bhagwat, B. Seiler, M. Costanzo et al., Identification of a Novel Lysophospholipid Acyltransferase in Saccharomyces cerevisiae, Journal of Biological Chemistry, vol.282, issue.42, pp.30562-30569, 2007.
DOI : 10.1074/jbc.M706326200

A. Jandrositz, J. Petschnigg, R. Zimmermann, K. Natter, H. Scholze et al., The lipid droplet enzyme Tgl1p hydrolyzes both steryl Kerscher The complete mitochondrial genome of Yarrowia lipolytica, Comp Funct Genom, vol.2, pp.80-90, 2001.

D. A. Keys and L. Mcalister-henn, Subunit structure, expression, and function of NAD(H)-specific isocitrate dehydrogenase in Saccharomyces cerevisiae., Journal of Bacteriology, vol.172, issue.8, pp.4280-4287, 1990.
DOI : 10.1128/jb.172.8.4280-4287.1990

J. Kiel, M. Veenhuis, and I. J. Van-der-klei, PEX Genes in Fungal Genomes: Common, Rare or Redundant, Traffic, vol.24, issue.10, pp.1291-1303, 2006.
DOI : 10.1111/j.1600-0854.2006.00479.x

K. Kim, M. S. Rosenkrantz, and L. Guarente, Saccharomyces cerevisiae contains two functional citrate synthase genes., Molecular and Cellular Biology, vol.6, issue.6, pp.1936-1942, 1986.
DOI : 10.1128/MCB.6.6.1936
URL : https://www.ncbi.nlm.nih.gov/pmc/articles/PMC367731/pdf

J. J. Kim and R. Miura, Acyl-CoA dehydrogenases and acyl-CoA oxidases. Structural basis for mechanistic similarities and differences, European Journal of Biochemistry, vol.11, issue.3, pp.483-493, 2004.
DOI : 10.1107/S0021889891004399

R. Köffel, R. Tiwari, L. Falquet, and R. Schneiter, The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 Genes Encode a Novel Family of Membrane-Anchored Lipases That Are Required for Steryl Ester Hydrolysis, Molecular and Cellular Biology, vol.25, issue.5, pp.1655-68, 2005.
DOI : 10.1128/MCB.25.5.1655-1668.2005

G. M. Kostner and P. Laggner, Chemical and physical properties of lipoproteins, Clinical Biochemistry-Human Plasma Lipoproteins, pp.23-54, 1989.

0. Kuge, M. Nishijima, and Y. Akamatsu, Phosphatidylserine biosynthesis in cultured Chinese hamster ovary cells. III. Genetic evidence for utilization of phosphatidylcholine and phosphatidylethanolamine as precursors, J. Bioi. Chem, vol.261, pp.5795-98, 1986.

M. Kujau, H. Weber, and G. Barth, Characterization of mutants of the yeastYarrowia lipolytica defective in acetyl-coenzyme a synthetase, Yeast, vol.95, issue.3, pp.193-203, 1992.
DOI : 10.1002/yea.320080305

M. Kunze, F. Kragler, M. Binder, A. Hartig, and A. Gurvitz, cells depends on growth on oleic acid medium, European Journal of Biochemistry, vol.15, issue.3, pp.915-922, 2002.
DOI : 10.1046/j.0014-2956.2001.02727.x

C. P. Kurtzman, New species and a new combination in the Hyphopichia and Yarrowia yeast clades, Antonie van Leeuwenhoek, vol.42, issue.2, pp.121-151, 2005.
DOI : 10.1007/s10482-005-2495-0

C. P. Kurtzman and C. J. Robnett, Identification and phylogeny of ascomycetous yeasts from analysis of nuclear large subunit (26S) ribosomal DNA partial sequences, Antonie van Leeuwenhoek, vol.73, issue.4, pp.331-71, 1998.
DOI : 10.1023/A:1001761008817

P. B. Lazarow, Genetic approaches to studying peroxisome biogenesis, Trends in Cell Biology, vol.3, issue.3, pp.89-93, 1993.
DOI : 10.1016/0962-8924(93)90079-G

R. Leber, E. Zinser, G. Zellnig, F. Paltauf, and G. Daum, Characterization of lipid particles of the yeast,Saccharomyces cerevisiae, Yeast, vol.175, issue.11, pp.1421-1428, 1994.
DOI : 10.1002/yea.320101105

R. Lehner and A. Kuksis, Triacylglycerol synthesis by an sn-1,3)- diacylglycerol transacylase from rat intestinal microsomes, J. Biol. Chem, vol.2, issue.268, pp.8781-8786, 1993.

R. Lehner and A. Kuksis, Biosynthesis of triacylglycerols, Progress in Lipid Research, vol.35, issue.2, pp.169-201, 1996.
DOI : 10.1016/0163-7827(96)00005-7

A. S. Lewin, V. Hines, and G. M. Small, Citrate synthase encoded by the CIT2 gene of Saccharomyces cerevisiae is peroxisomal., Molecular and Cellular Biology, vol.10, issue.4, pp.1399-1405, 1990.
DOI : 10.1128/MCB.10.4.1399

G. Li, S. Chen, M. N. Thompson, and M. L. Greenberg, New insights into the regulation of cardiolipin biosynthesis in yeast: Implications for Barth syndrome, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1771, issue.3, pp.432-441, 2007.
DOI : 10.1016/j.bbalip.2006.06.007

X. Liao and R. A. Butow, RTG1 and RTG2: Two yeast genes required for a novel path of communication from mitochondria to the nucleus, Cell, vol.72, issue.1, pp.61-71, 1993.
DOI : 10.1016/0092-8674(93)90050-Z

R. Lill and W. Neupert, Mechanisms of protein import across the mitochondrial outer membrane, Trends in Cell Biology, vol.6, issue.2, pp.56-61, 1996.
DOI : 10.1016/0962-8924(96)81015-4

M. C. Lorenz and G. R. Fink, The glyoxylate cycle is required for fungal virulence, Nature, vol.412, issue.6842, pp.83-89, 2001.
DOI : 10.1038/35083594

Y. S. Luo, J. M. Nicaud, P. P. Van-veldhoven, and T. Chardot, The acyl???CoA oxidases from the yeast Yarrowia lipolytica: characterization of Aox2p, Archives of Biochemistry and Biophysics, vol.407, issue.1, pp.32-40, 2002.
DOI : 10.1016/S0003-9861(02)00466-6

Y. S. Luo, H. J. Wang, K. V. Gopalan, D. K. Srivastava, J. M. Nicaud et al., Purification and Characterization of the Recombinant Form of Acyl CoA Oxidase 3 from the Yeast Yarrowia lipolytica, Archives of Biochemistry and Biophysics, vol.384, issue.1, pp.1-8, 2000.
DOI : 10.1006/abbi.2000.2079

Y. Luo, H. Wang, K. V. Gopalan, D. K. Srivastava, J. Nicaud et al., Purification and Characterization of the Recombinant Form of Acyl CoA Oxidase 3 from the Yeast Yarrowia lipolytica, Archives of Biochemistry and Biophysics, vol.384, issue.1, pp.1-8, 2000.
DOI : 10.1006/abbi.2000.2079

Y. Luo, J. Nicaud, P. Van-veldhoven, and T. Chardot, The acyl???CoA oxidases from the yeast Yarrowia lipolytica: characterization of Aox2p, Archives of Biochemistry and Biophysics, vol.407, issue.1, pp.32-38, 2002.
DOI : 10.1016/S0003-9861(02)00466-6

M. Luttik, P. Kötter, F. Salomons, I. Van-der-klei, J. Van-dijken et al., The Saccharomyces cerevisiae ICL2 Gene Encodes a Mitochondrial 2-Methylisocitrate Lyase Involved in Propionyl-Coenzyme A Metabolism, Journal of Bacteriology, vol.182, issue.24, pp.7007-7020, 2000.
DOI : 10.1128/JB.182.24.7007-7013.2000

C. Madzak, C. Gaillardin, and J. Beckerich, Heterologous protein expression and secretion in the non-conventional yeast Yarrowia lipolytica: a review, Journal of Biotechnology, vol.109, issue.1-2, pp.63-81, 2004.
DOI : 10.1016/j.jbiotec.2003.10.027

C. J. Mann, T. Mitchell, and J. S. Nishimura, Phosphorylation and formation of hybrid enzyme species test the "half of sites" reactivity of Escherichia coli succinyl-CoA synthetase, Biochemistry, vol.30, issue.6, pp.1497-1503, 1991.
DOI : 10.1021/bi00220a008

S. Matoba, J. Fukayama, R. Wing, and D. Ogrydziak, Intracellular precursors and secretion of alkaline extracellular protease of Yarrowia lipolytica., Molecular and Cellular Biology, vol.8, issue.11, pp.4904-4920, 1988.
DOI : 10.1128/MCB.8.11.4904

M. Matsuoka, Y. Ueda, and S. Aiba, Role and control of isocitrate lyase in Candida lipolytica, J.Bacteriol, vol.144, pp.692-699, 1980.

L. Mcalister-henn and L. M. Thompson, Isolation and expression of the gene encoding yeast mitochondrial malate dehydrogenase., Journal of Bacteriology, vol.169, issue.11, pp.5157-66, 1987.
DOI : 10.1128/jb.169.11.5157-5166.1987

J. Mclean, C. Fielding, D. Drayna, . Dieplinger, H. Baer et al., Cloning and expression of human lecithincholesterol acyltransferase cDNA, Proc. Natl. Acad. Sci, pp.2335-2339, 1986.

C. R. Mcmaster and R. M. Bell, Phosphatidylcholine biosynthesis in Saccharomyces cerevisiae : Regulatory insights from studies employing null and chimeric sn- 1, 2-diacylglycerol choline and ethanolamine phosphotransferases, J Biol Chem, vol.269, pp.28010-28016, 1994.

M. Mekouar, I. Blanc-lenfle, C. Ozanne, D. Silva, C. Cruaud et al., Detection and analysis of alternative splicing in Yarrowia lipolytica reveal structural constraints facilitating nonsense-mediated decay of intron-retaining transcripts, Genome Biology, vol.11, issue.6, p.65, 2010.
DOI : 10.1186/gb-2010-11-6-r65

K. I. Minard and L. Mcalister-henn, Isolation, nucleotide sequence analysis, and disruption of the MDH2 gene from Saccharomyces cerevisiae: evidence for three isozymes of yeast malate dehydrogenase., Molecular and Cellular Biology, vol.11, issue.1, pp.370-80, 1991.
DOI : 10.1128/MCB.11.1.370

J. Nicaud, Lipid accumulation, lipid body formation, and acyl coenzyme A oxidases of yeast Yarrowia lipolytica, Appl. Envir.Microbiol, vol.70, pp.3918-3924, 2004.

D. Montet, R. Ratomahenina, P. Galzy, M. Pina, and . J. Graille, A study of the influence of the growth media on the fatty acid composition inCandida lipolytica diddens and lodder, Biotechnology Letters, vol.72, issue.10, pp.733-736, 1985.
DOI : 10.1007/BF01032285

E. Morzycka, D. Sawnor-korszy?ska, A. Paszewski, J. Grabski, and K. Raczy?ska-bojanowska, Methionine overproduction by Saccharomycopsis lipolytica, Appl Environ Microbiol, vol.32, pp.125-155, 1976.

H. Müllner and G. Daum, Dynamics of neutral lipid storage in yeast, Acta Biochim Pol, vol.51, pp.323-370, 2004.

N. Murata and Y. Tasaka, Glycerol-3-phosphate acyltransferase in plants, Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol.1348, issue.1-2, pp.10-16, 1997.
DOI : 10.1016/S0005-2760(97)00115-X

D. J. Murphy, The biogenesis and functions of lipid bodies in animals, plants and microorganisms, Progress in Lipid Research, vol.40, issue.5, pp.325-438, 2001.
DOI : 10.1016/S0163-7827(01)00013-3

G. L. Murphy and J. J. Perry, Assimilation of chlorinated alkanes by hydrocarbonutilizing fungi, Bacteriol, vol.160, pp.1171-1175, 1984.

K. Nadra, A. S. De-preux-charles, J. J. Médard, W. T. Hendriks, G. S. Han et al., Phosphatidic acid mediates demyelination in Lpin1 mutant mice, Genes & Development, vol.22, issue.12, pp.1647-61, 2008.
DOI : 10.1101/gad.1638008

M. Nanjundan and F. Possmayer, Pulmonary phosphatidic acid phosphatase and lipid phosphate phosphohydrolase, American Journal of Physiology - Lung Cellular and Molecular Physiology, vol.284, issue.1, pp.1-23, 2003.
DOI : 10.1152/ajplung.00029.2002

E. Naumova, G. Naumov, P. Fournier, H. Nguyen, and C. Gaillardin, Chromosomal polymorphism of the yeast Yarrowia lipolytica and related species: electrophoretic karyotyping and hybridization with cloned genes, Current Genetics, vol.1, issue.5-6, pp.450-454, 1993.
DOI : 10.1007/BF00312633

J. Nicaud, E. Fabre, and C. Gaillardin, Expression of invertase activity in Yarrowia lipolytica and its use as a selective marker, Current Genetics, vol.33, issue.4, pp.253-60, 1989.
DOI : 10.1007/BF00422111

J. M. Nicaud, C. Madzak, P. Van-den-broek, G. Gysler, P. Duboc et al., Protein expression and secretion in the yeast Yarrowia lipolytica, FEMS Yeast Res, vol.2, pp.371-379, 2002.

J. Nikawa and S. Yamashita, Characterization of phosphatidylserine synthase from saccharomyces cerevisiae and a mutant defective in the enzyme, Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol.665, issue.3, pp.420-446, 1981.
DOI : 10.1016/0005-2760(81)90254-X

J. S. Nishimura, Succinyl-CoA synthetase structure-functionrelationships and other considerations, Adv. Enzymol, vol.58, p.1412172, 1986.
DOI : 10.1002/9780470123041.ch4

R. M. Nitsch, J. K. Blusztajn, A. G. Pittas, B. E. Slack, J. H. Growdon et al., Evidence for a membrane defect in Alzheimer disease brain., Proceedings of the National Academy of Sciences, vol.89, issue.5, pp.1671-1675, 1992.
DOI : 10.1073/pnas.89.5.1671

W. M. Nuttley, A. M. Brade, C. Gaillardin, G. A. Eitzen, J. R. Glover et al., Rapid identification and characterization of peroxisomal assembly mutants inYarrowia lipolytica, Yeast, vol.14, issue.5, pp.507-517, 1993.
DOI : 10.1002/yea.320090506

E. J. Nyns, J. P. Auquiere, . Chiang, and A. L. Wiaux, Comparative growth of Candida lipolytica on glucose and n-hexadecane Nature, pp.177-185, 1967.

P. Oelkers, D. Cromley, M. Padamsee, J. T. Billheime, and S. L. Sturley, The DGA1 Gene Determines a Second Triglyceride Synthetic Pathway in Yeast, Journal of Biological Chemistry, vol.277, issue.11, pp.8877-8881, 2002.
DOI : 10.1074/jbc.M111646200

D. Ogrydziak, Development of genetic maps of non-conventional yeasts, Journal of Basic Microbiology, vol.125, issue.3, pp.185-96, 1988.
DOI : 10.1002/jobm.3620280307

D. Ogrydziak, Yeast Extracellular Proteases, Critical Reviews in Biotechnology, vol.57, issue.1, pp.1-55, 1993.
DOI : 10.1080/00021369.1991.10870614

M. Oogaki, T. Nakahara, H. Uchiyama, and T. Tabuchi, Extracellular production of D-(+)-2-hydroxyglutaric acid by Yarrowia lipolytica from glucose under thiaminedeficient conditions, Agric Biol Chem, vol.47, pp.2619-2624, 1983.

S. Papanikolaou and G. Aggelis, Lipid production by Yarrowia lipolytica growing on industrial glycerol in a single-stage continuous culture, Bioresource Technology, vol.82, issue.1, pp.43-49, 2002.
DOI : 10.1016/S0960-8524(01)00149-3

S. Papanikolaou, I. Chevalot, M. Komaitis, J. Nicaud, and G. Aggelis, Single cell oil production by Yarrowia lipolytica growing on an industrial derivative of animal fat in batch cultures, Applied Microbiology and Biotechnology, vol.58, issue.3, pp.308-312, 2002.
DOI : 10.1007/s00253-001-0897-0

J. L. Patton-vogt, P. Griac, A. Sreenivas, V. Bruno, S. Dowd et al., Role of the Yeast Phosphatidylinositol/Phosphatidylcholine Transfer Protein (Sec14p) in Phosphatidylcholine Turnover andINO1 Regulation, Journal of Biological Chemistry, vol.272, issue.33, pp.20873-20883, 1997.
DOI : 10.1074/jbc.272.33.20873

M. Péterfy, J. Phan, P. Xu, and K. Reue, Lipodystrophy in the fld mouse results from mutation of a new gene encoding a nuclear protein, lipin, Nat Gen, vol.27, pp.121-124, 2001.

N. Pfanner, E. A. Craig, and M. Meijer, The protein import machine of the mitochondrial inner membrane, Trends in Biochemical Sciences, vol.19, issue.9, pp.368-72, 1994.
DOI : 10.1016/0968-0004(94)90113-9

M. G. Pillai, M. Certik, T. Nakahara, and Y. Kamisaka, Characterization of triacylglycerol biosynthesis in subcellular fractions of an oleaginous fungus, Mortierella ramanniana var. angulispora, Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, vol.1393, issue.1, pp.128-136, 1998.
DOI : 10.1016/S0005-2760(98)00069-1

P. E. Purdue and P. B. Lazarow, Peroxisomal biogenesis: multiple pathways of protein import, J Biol Chem, vol.269, pp.30065-30073, 1994.

P. E. Purdue, X. Yang, and P. B. Lazarow, Pex18p and Pex21p, a Novel Pair of Related Peroxins Essential for Peroxisomal Targeting by the PTS2 Pathway, The Journal of Cell Biology, vol.129, issue.7, pp.1859-69, 1998.
DOI : 10.1083/jcb.132.3.325

S. Rajakumari, K. Grillitsch, and G. Daum, Synthesis and turnover of non-polar lipids in yeast, Progress in Lipid Research, vol.47, issue.3, pp.157-171, 2008.
DOI : 10.1016/j.plipres.2008.01.001

C. S. Ratledge, . Kamel, and Y. Kakuda, Yeasts, moulds, algae and bacteria as sources of lipids. Technological advances in improved and alternative sources of lipids, academic and professional, pp.235-291, 1994.

N. Regev-rudzki, S. Karniely, N. N. Ben-haim, and O. Pines, Yeast Aconitase in Two Locations and Two Metabolic Pathways: Seeing Small Amounts Is Believing, Molecular Biology of the Cell, vol.16, issue.9, pp.4163-71, 2005.
DOI : 10.1091/mbc.E04-11-1028

T. Rickey and A. S. Lewin, Extramitochondrial citrate synthase activity in bakers' yeast., Molecular and Cellular Biology, vol.6, issue.2, pp.488-493, 1986.
DOI : 10.1128/MCB.6.2.488

W. R. Riekhof and D. Voelker, Uptake and Utilization of Lyso-phosphatidylethanolamine by Saccharomyces cerevisiae, Journal of Biological Chemistry, vol.281, issue.48, pp.36588-36596, 2006.
DOI : 10.1074/jbc.M608851200

S. L. Roderick and L. J. Banaszak, The three-dimensional structure of porcine heart mitochondrial malate dehydrogenase at 3.0-A resolution, J. Biol. Chem, vol.261, pp.9461-9464, 1986.

C. W. Roermund, R. Drissen, . Van-den, M. Berg, L. Ijlst et al., Identification of a Peroxisomal ATP Carrier Required for Medium-Chain Fatty Acid ??-Oxidation and Normal Peroxisome Proliferation in Saccharomyces cerevisiae, Molecular and Cellular Biology, vol.21, issue.13, pp.4321-4330, 2001.
DOI : 10.1128/MCB.21.13.4321-4329.2001

M. Rosenkrantz, T. Alam, K. S. Kim, B. J. Clark, P. A. Srere et al., Mitochondrial and nonmitochondrial citrate synthases in Saccharomyces cerevisiae are encoded by distinct homologous genes., Molecular and Cellular Biology, vol.6, issue.12, pp.4509-4515, 1986.
DOI : 10.1128/MCB.6.12.4509

J. Routaboul, C. Benning, N. Bechtold, M. Caboche, and L. Lepiniec, The TAG1 locus of Arabidopsis encodes for a diacylglycerol acyltransferase, Plant Physiology and Biochemistry, vol.37, issue.11, pp.831-840, 1999.
DOI : 10.1016/S0981-9428(99)00115-1

S. A. Rudge, T. R. Pettitt, C. Zhou, M. J. Wakelam, and J. A. Engebrecht, SPO14 separation-of-function mutations define unique roles for phospholipase D in secretion and cellular differentiation in Saccharomyces cerevisiae, Genetics, vol.158, pp.1431-1444, 2001.

J. Sambrook, T. Maniatis, and E. F. Fritsch, Molecular cloning: a laboratory manual, 1989.

L. Sandager, M. Gustavsson, U. Stahl, A. Dahlqvist, E. Wiberg et al., Storage Lipid Synthesis Is Non-essential in Yeast, Journal of Biological Chemistry, vol.277, issue.8, 2002.
DOI : 10.1074/jbc.M109109200

G. Schatz and B. Dobberstein, Common Principles of Protein Translocation Across Membranes, Science, vol.271, issue.5255, pp.1519-1545, 1996.
DOI : 10.1126/science.271.5255.1519

A. L. Schilmiller, A. J. Koo, and G. A. Howe, Functional diversification of acylcoenzyme A oxidases in jasmonic acid biosynthesis and action Plant Physiol, pp.812-824, 2007.

S. B. Settlage, R. F. Wilson, and P. Kwanyuen, Localization of diacylglycérol acyltransferase to oil body associated endoplasmic reticulum, Plant Physiol. Biochem, vol.33, pp.399-407, 1995.

P. Simms and D. Ogrydziak, Structural gene for the alkaline extracellular protease of Saccharomycopsis lipolytica, J Bacteriol, vol.145, pp.404-413, 1981.

E. Raber, R. H. , F. Jr, and R. V. , Obesity resistance and multiple mechanisms of triglyceride synthesis in mice lacking Dgat, Nat. Genet, vol.25, pp.87-90, 1999.

D. Sorger and G. Daum, Synthesis of Triacylglycerols by the Acyl-Coenzyme A:Diacyl-Glycerol Acyltransferase Dga1p in Lipid Particles of the Yeast Saccharomyces cerevisiae, Journal of Bacteriology, vol.184, issue.2, pp.519-543, 2002.
DOI : 10.1128/JB.184.2.519-524.2002

D. Sorger and G. Daum, Triacylglycerol biosynthesis in yeast, Applied Microbiology and Biotechnology, vol.267, issue.4, pp.289-299, 2003.
DOI : 10.1007/s00253-002-1212-4

D. Sorger, K. Athenstaedt, C. Hrastnik, and G. Daum, A Yeast Strain Lacking Lipid Particles Bears a Defect in Ergosterol Formation, Journal of Biological Chemistry, vol.279, issue.30, pp.31190-31196, 2004.
DOI : 10.1074/jbc.M403251200

J. S. Steffan and L. Mcalister-henn, Isolation and characterization of the yeast gene encoding the MDH3 isozyme of malate dehydrogenase, J Biol Chem, vol.267, pp.24708-24723, 1992.

J. S. Steffan, K. I. Minard, and L. Mcalister-henn, Expression and function of heterologous forms of malate dehydrogenase in yeast, Archives of Biochemistry and Biophysics, vol.293, issue.1, pp.93-102, 1992.
DOI : 10.1016/0003-9861(92)90370-C

T. Sugimoto, S. Kanamasa, T. Kato, and E. Y. Park, Importance of malate synthase in the glyoxylate cycle of Ashbya gossypii for the efficient production of riboflavin, Applied Microbiology and Biotechnology, vol.109, issue.1, 2009.
DOI : 10.1007/s00253-009-1972-1

M. Suissa, K. Suda, and G. Schatz, Isolation of the nuclear yeast genes for citrate synthase and fifteen other mitochondrial proteins by a new screening method, EMBO J, vol.3, pp.1773-81, 1984.

S. Taketani, T. Osumi, and H. Katsuki, Characterization of sterol-ester hydrolase in Saccharomyces cerevisiae, Biochimica et Biophysica Acta (BBA) - Enzymology, vol.525, issue.1, pp.87-92, 1978.
DOI : 10.1016/0005-2744(78)90202-4

L. M. Thompson, P. Sutherland, J. S. Steffan, and L. Mcalister-henn, Gene sequence and primary structure of mitochondrial malate dehydrogenase from Saccharomyces cerevisiae, Biochemistry, vol.27, issue.22, pp.8393-8400, 1988.
DOI : 10.1021/bi00422a015

L. M. Thompson and L. Mcalister-henn, Dispensable presequence for cellular localization and function of mitochondrial malate dehydrogenase from Saccharomyces cerevisiae, J Biol Chem, vol.264, pp.12091-12097, 1989.

S. Trajkovic-bodennec, J. Bodennec, and A. H. Futerman, Phosphatidylcholine metabolism is altered in a monocyte-derived macrophage model of Gaucher disease but not in lymphocytes, Blood Cells, Molecules, and Diseases, vol.33, issue.1, pp.77-82, 2004.
DOI : 10.1016/j.bcmd.2004.03.001
URL : https://hal.archives-ouvertes.fr/hal-00069560

B. Y. Treton and H. Et-heslot, Etude de quelques propriétés de l " aconitase de la levure Saccharomycopsis lipolytica, Agric Biol Chem, vol.42, pp.1201-1206, 1978.

S. Triki, C. Demandre, and P. Mazliak, Biosynthesis of triacylglycerols by developing sunflower seed microsomes, Phytochemistry, vol.52, issue.1, pp.55-62, 1999.
DOI : 10.1016/S0031-9422(99)00064-3

W. J. Van-der and J. A. Von-arx, The yeast genus Yarrowia gen. nov., Antonie van Leeuwenhoek, vol.38, issue.6, pp.517-538, 1980.
DOI : 10.1007/BF00394008

C. W. Van-roermund, Y. Elgersma, . N. Singh, R. J. Wanders, and H. F. Tabak, The membrane of peroxisomes in Saccharomyces cerevisiae is impermeable to NAD (H) and acetyl-CoA under in vivo conditions, EMBO J, vol.14, issue.14, pp.3480-3486, 1995.

C. W. Van-roermund, E. H. Hettema, A. J. Kal, M. Van-den-berg, H. F. Tabak et al., Peroxisomal beta -oxidation of polyunsaturated fatty acids in Saccharomyces cerevisiae: isocitrate dehydrogenase provides NADPH for reduction of double bonds at even positions, The EMBO Journal, vol.17, issue.3, pp.677-87, 1998.
DOI : 10.1093/emboj/17.3.677

P. Vanni, E. Giachetti, G. Pinzauti, and A. Mcfadden, Comparative structure, function and regulation of isocitrate lyase, an important assimilatory enzyme, Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, vol.95, issue.3, pp.431-58, 1990.
DOI : 10.1016/0305-0491(90)90002-B

L. Vernis, L. Poljak, M. Chasles, K. Uchida, S. Casarégola et al., Only Centromeres Can Supply the Partition System Required for ARS Function in the Yeast Yarrowia lipolytica, Journal of Molecular Biology, vol.305, issue.2, pp.203-217, 2001.
DOI : 10.1006/jmbi.2000.4300

D. R. Voelker and J. L. Frazier, Isolation and characterization of a Chinese hamster ovary cell line requiring ethanolamine or phosphatidylserine for growth and exhibiting defective phosphatidylserine synthase activity, J Biol Chem, vol.261, pp.1002-1010, 1986.

D. R. Voelker, Interorganelle transport of aminoglycerophospholipids, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1486, issue.1, pp.97-107, 2000.
DOI : 10.1016/S1388-1981(00)00051-2

A. Wagner, K. Grillitsch, E. Leitner, and . G. Daum, Mobilization of steryl esters from lipid particles of the yeast Saccharomyces cerevisiae, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1791, issue.2, pp.118-142, 2009.
DOI : 10.1016/j.bbalip.2008.11.004

H. Wang, L. Clainche, A. , L. Dall, M. Waché et al., Cloning and characterization of the peroxisomal acyl CoA oxidase ACO3 gene from the alkane???utilizing yeast Yarrowia lipolytica, Yeast, vol.14, issue.15, pp.1373-1386, 1998.
DOI : 10.1002/(SICI)1097-0061(199811)14:15<1373::AID-YEA332>3.3.CO;2-T
URL : https://hal.archives-ouvertes.fr/hal-00368240

H. Wang, L. Dall, M. Waché, Y. Laroche, P. Belin et al., Cloning, sequencing, and characterization of five genes coding for Acyl-CoA oxidase isozymes in the yeastYarrowia lipolytica, Cell Biochemistry and Biophysics, vol.10, issue.2, pp.165-174, 1999.
DOI : 10.1007/BF02738170

H. J. Wang, L. Dall, M. T. Wach, Y. Laroche, C. Belin et al., Evaluation of acyl coenzyme A oxidase (Aox) isozyme function in the n-alkane-assimilating yeast Yarrowia lipolytica, J. Bacteriol, vol.181, pp.5140-5148, 1999.
URL : https://hal.archives-ouvertes.fr/hal-00368242

T. Wang, Y. Luo, and G. M. Small, The POX1 gene encoding peroxisomal acyl- CoA oxidase in Saccharomyces cerevisiae is under the control of multiple regulatory elements, J Biol Chem, vol.269, pp.24480-24485, 1994.

P. F. Weller and A. M. Dvorac, Lipid bodies: Intracellular sites for eicosanoid formation, Journal of Allergy and Clinical Immunology, vol.94, issue.6, pp.1152-1156, 1994.
DOI : 10.1016/0091-6749(94)90325-5

L. J. Wickerham, C. P. Kurtzman, and A. I. Herman, Sexual Reproduction in Candida lipolytica, Science, vol.167, issue.3921, p.1141, 1970.
DOI : 10.1126/science.167.3921.1141

W. T. Wolodko, M. E. Fraser, M. N. James, and W. A. Bridger, The crystal structure of succinyl-CoA synthetase from Escherichia coli at 2.5-A resolution, J. Biol. Chem, vol.269, pp.10883-10890, 1994.

H. Yang, M. Bard, D. A. Bruner, A. Gleeson, R. J. Deckelbaum et al., Sterol Esterification in Yeast: A Two-Gene Process, Science, vol.272, issue.5266, pp.1353-1356, 1996.
DOI : 10.1126/science.272.5266.1353

D. Yarrow, Four new combinations in yeasts, Antonie van Leeuwenhoek, vol.35, issue.1, pp.357-60, 1972.
DOI : 10.1007/BF02328105

C. Yu, J. Kennedy, C. C. Chang, and J. A. Rothblatt, Molecular cloning and characterization of two isoforms of Saccharomyces cerevisiae acyl-CoA:sterol acyltransferase, J. Biol. Chem, vol.271, pp.24157-24163, 1996.

Y. Zhang and C. O. Rock, Thematic Review Series: Glycerolipids. Acyltransferases in bacterial glycerophospholipid synthesis, The Journal of Lipid Research, vol.49, issue.9, pp.1867-1874, 2008.
DOI : 10.1194/jlr.R800005-JLR200

Z. Zheng and J. Zou, The Initial Step of the Glycerolipid Pathway. IDENTIFICATION OF GLYCEROL 3-PHOSPHATE/DIHYDROXYACETONE PHOSPHATE DUAL SUBSTRATE ACYLTRANSFERASES IN SACCHAROMYCES CEREVISIAE, Journal of Biological Chemistry, vol.276, issue.45, pp.41710-41716, 2001.
DOI : 10.1074/jbc.M104749200

R. Zimmermann, J. G. Strauss, G. Haemmerle, G. Schoiswohl, R. Birner-grünberger et al., Fat Mobilization in Adipose Tissue Is Promoted by Adipose Triglyceride Lipase, Science, vol.306, issue.5700, pp.1383-1386, 2004.
DOI : 10.1126/science.1100747

E. Zinser, F. Paltauf, and G. Daum, Sterol composition of yeast organelle membranes and subcellular distribution of enzymes involved in sterol metabolism., Journal of Bacteriology, vol.175, issue.10, pp.2853-2861, 1993.
DOI : 10.1128/jb.175.10.2853-2858.1993

B. K. Zolman, A. Yoder, and B. Bartel, Genetic analysis of indole-3-butyric acid responses in Arabidopsis thaliana reveals four mutant classes, Genetics, vol.156, pp.1323-1337, 2000.

J. Zou, Y. Wei, C. Jako, A. Kumar, G. Selvaraj et al., The Arabidopsis thaliana TAG1 mutant has a mutation in a diacylglycerol acyltransferase gene, The Plant Journal, vol.272, issue.6, 1999.
DOI : 10.1074/jbc.271.39.24157

D. Zweytick, K. Athenstaedt, and G. Daum, Intracellular lipid particles of eukaryotic cells, Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, vol.1469, issue.2, pp.101-120, 2000.
DOI : 10.1016/S0005-2736(00)00294-7