]. B. Liedberg, C. Liedberg, I. Nylander, and . Lundström, Surface plasmon resonance for gas detection and biosensing, Sensors and Actuators, vol.4, pp.299-304, 1983.
DOI : 10.1016/0250-6874(83)85036-7

]. M. Linder, S. Elstein, J. Wallace, and P. Lindner, Solar blind bandpass filters for UV imaging devices, Proc. SPIE, pp.176-183, 1998.

]. W. Lukosz and K. Tiefenthaler, Directional switching in planar waveguides effected by adsorption?desorption processes, Proceedings of the Second European Conference on Integrated Optics, pp.152-155, 1983.

]. W. Lukosz, P. M. Nellen, C. Stamm, and P. Weiss, Output grating couplers on planar waveguides as integrated optical chemical sensors, Sensors and Actuators B: Chemical, vol.1, issue.1-6, pp.585-588, 1990.
DOI : 10.1016/0925-4005(90)80278-8

G. Cerovic, G. Escalier, M. Béna, L. Guéron, F. Mcdonagh et al., Innovative integrated system for real-time measurement of hybridization and melting on standard format microarrays, BioTechniques, vol.44, issue.7, pp.913-920, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00814717

]. P. Mellot, Y. Mechulam, D. Lecorre, S. Blanquet, and G. Fayat, Identification of an amino acid region supporting specific methionyl-tRNA synthetase: tRNA recognition, Journal of Molecular Biology, vol.208, issue.3, pp.429-443, 1989.
DOI : 10.1016/0022-2836(89)90507-X

]. S. Mendes and S. S. Saavedra, On probing molecular monolayers: a spectroscopic optical waveguide approach of ultra-sensitivity, Optics Express, vol.4, issue.11, pp.449-456, 1999.
DOI : 10.1364/OE.4.000449

]. B. Möhrle, K. Köhler, J. Jaehrling, R. Brock, and G. Günter, Label-free characterization of cell adhesion using reflectometric interference spectroscopy (RIfS), Analytical and Bioanalytical Chemistry, vol.24, issue.4, pp.407-413, 2006.
DOI : 10.1007/s00216-005-0202-7

. Canva, Absorption and related optical dispersion effects on the spectral response of a surface plasmon resonance sensor, Applied Optics, vol.47, issue.33, pp.6177-6182, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00629009

]. P. Nellen, K. Tiefenthaler, and W. Lukosz, Integrated optical input grating couplers as biochemical sensors, Sensors and Actuators, vol.15, issue.3, pp.285-295, 1998.
DOI : 10.1016/0250-6874(88)87017-3

B. Clark, G. Trotter, and . Moddel, Fixed polarizer ellipsometry for simple and sensitive detection of thin films generated by specific molecular interactions: applications in immunoassays and DNA sequence detection, Clinical Chemistry, 1998.

]. C. Pace, F. Vajdos, L. Fee, G. Grimsley, and T. Gray, How to measure and predict the molar absorption coefficient of a protein, Protein Science, vol.33, issue.11, pp.2411-2423, 1995.
DOI : 10.1002/pro.5560041120

]. J. Reverchon, C. Meyer, G. Mazzeo, and S. Cassette, UV imaging of biochips: limitations of contrast, Optically Based Biological and Chemical Detection for Defence III, 2006.
DOI : 10.1117/12.689965

]. K. Robin, J. L. Reverchon, L. Mugherli, M. Fromant, P. Plateau et al., Detection of biological macromolecules on a biochip dedicated to UV specific absorption, Biosensors and Bioelectronics, vol.24, issue.6, pp.1585-1591, 2009.
DOI : 10.1016/j.bios.2008.08.028
URL : https://hal.archives-ouvertes.fr/hal-00567022

]. K. Robin, J. L. Reverchon, L. Mugherli, M. Fromant, and H. Benisty, Biodetection of DNA and proteins using enhanced UV absorption by structuration of the chip surface, Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications VI, 2009.
DOI : 10.1117/12.808124
URL : https://hal.archives-ouvertes.fr/hal-00573363

]. K. Schmitt, B. Schirmer, C. Hoffmann, A. Brandenburg, and P. Meyrueis, Interferometric biosensor based on planar optical waveguide sensor chips for label-free detection of surface bound bioreactions, Biosensors and Bioelectronics, vol.22, issue.11, pp.2591-2597, 2007.
DOI : 10.1016/j.bios.2006.10.016

]. K. Schmitt, K. Oehse, G. Sulz, and C. Hoffmann, Evanescent field Sensors Based on Tantalum Pentoxide Waveguides ??? A Review, Sensors, vol.8, issue.2, pp.711-738, 2008.
DOI : 10.3390/s8020711

]. D. Söll, U. L. Rajbhandary-]-n, S. Sugimoto, M. Nakano, K. Yoneyama et al., tRNA : structure, biosynthesis and function " [SRU Biosystems] http://www.srubiosystems.com Improved thermodynamic parameters and helix initiation factor to predict stability of DNA duplexes, Nucleic Acids Research, vol.24, pp.4501-4505, 1994.

]. S. Takashima, Ultra-violet Absorption Spectra of Proteins in Deuterium Oxide, Nature, vol.70, issue.4737, pp.597-598, 1960.
DOI : 10.1021/ja01283a004

]. A. Tataurov, Y. You, R. M. Owczarzy-]-e, and . Yeatman, Predicting ultraviolet spectrum of single stranded and double stranded deoxyribonucleic acids Resolution and sensitivity in surface plasmon microscopy and sensing, Biophys. Chem.biophysics.idtdna.com/ Biosensors and Bioelectronics, vol.1331, issue.11617, pp.66-70, 1996.

]. B. Seraphin, N. Bottka, ]. K. Robin, J. L. Reverchon, L. Mugherli et al., Franz-Keldysh Effect of the Refractive Index in SemiconductorsDesign of specific biochips for contrast enhancement of UV biological absorption Optimization and control of grating coupling to or from a silicon-based optical waveguide, Physisical Review SPIE Photonics West Optical Engeneering, vol.139, issue.35, pp.560-564, 1965.

]. P. Tien, Light Waves in Thin Films and Integrated Optics, Applied Optics, vol.10, issue.11, p.2395, 1971.
DOI : 10.1364/AO.10.002395

. Ishihara, Quasiguided modes and optical properties of photonic crystal slabs, Physical Review B, vol.66, issue.4, 2002.

. Vörös, The Density and Refractive Index of Adsorbing Protein Layers, Biophysical Journal, vol.87, issue.1, pp.553-551, 2004.
DOI : 10.1529/biophysj.103.030072

]. D. Windt-]-e and . Yeatman, IMD-Software for modeling the optical properties of multilayer films Resolution and sensitivity in surface plasmon microscopy and sensing, Computers in Physics Biosensors and Bioelectronics, vol.1211, issue.4, pp.360-370, 1996.

]. R. Références-[-bashara, N. M. Azzam, and . Bashara, Ellipsometry and polarized light, 1999.

]. D. Bruggeman-]-p, W. T. Cuypers, H. C. Hermens, . Hemker, G. Gliech et al., Calculation of various physical constants of heterogeneous substances Ellipsometry as a Tool to Study Protein Films at Liquid-Solid Interfaces Surface characterization techniques for determining the root-mean-square roughness and power spectral densities of optical components, Annalen der Physik Analytical Biochemistry Applied Optics, vol.24, issue.411, pp.636-679, 1935.

]. D. Goyal, G. K. Pribil, J. A. Woollam, A. Subramanian-]-g, J. L. Maezzo et al., Detection of ultrathin biological films using vacuum ultraviolet spectroscopic ellipsometry, Materials Science and Engineering: B, vol.149, issue.1, pp.26-33, 2006.
DOI : 10.1016/j.mseb.2007.11.034

. Canva, Absorption and related optical dispersion effects on the spectral response of a surface plasmon resonance sensor, Applied Optics, vol.47, issue.33, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00629009

]. E. Palik-]-p, L. M. Prêtre, A. Wu, J. D. Knoesen, and . Swalen, Handbook of Optical Constants of Solids Optical properties of nonlinear optical polymers: a method for calculation, Journal of the Optical Society of America B, vol.15, issue.1, 1998.

]. J. Reverchon, J. Robot, J. P. Truffer, J. P. Caumes, I. Mourad et al., AlGaN-based focal plane arrays for selective UV imaging at 310nm and 280nm and route toward deep UV imaging, Sensors, Systems, and Next-Generation Satellites XI, 2007.
DOI : 10.1117/12.754794

]. K. Robin, J. L. Reverchon, L. Mugherli, H. Benisty, ]. K. Robin et al., Detection of proteins and DNA on a biochip in UV Detection of biological macromolecules on a biochip dedicated to UV specific absorption Lorentz dispersion model The effective medium approximations: Some recent developments, Proceedings SPIE Trubetskov, A.A. Tikhonravov, and A, pp.7188-7192, 1998.

D. Brazas and L. Li, Effects of interface roughness on the spectral properties of thin films and multilayers The Density and Refractive Index of Adsorbing Protein Layers Analysis of input grating couplers having finite lengths, Applied Optics Biophysical Journal Références: [Brazas Applied Optics, vol.4234, issue.87, pp.553-551, 1995.

]. J. Brazas and L. Li, A method for achromatichally coupling a beam of light into a waveguide, U.S. patent, vol.5947, p.420, 1995.

]. K. Cottier, M. Wiki, G. Voirin, H. Gao, R. E. Kunz-]-d et al., Label-free highly sensitive detection of (small) molecules by wavelength interrogation of integrated optical chipsDispersion compensation for an integrated optic grating coupler utilizing a transmission volume hologram, Sensors and Actuators B: Chemical Applied Optics, vol.9113, issue.32, pp.241-251, 1993.

]. S. Mendes, L. Li, J. J. Burke, J. E. Lee, S. S. Saavedra-]-s et al., 70-nm-bandwidth achromatic waveguide coupler, Applied Optics, vol.34, issue.27, pp.6180-6186, 1995.
DOI : 10.1364/AO.34.006180

]. C. Palmer, Diffraction Grating Handbook, 2005.

]. O. Parriaux and G. J. Veldhuis, Normalized analysis for the sensitivity optimization of integrated optical evanescent-wave sensors, Journal of Lightwave Technology, vol.16, issue.4, pp.573-582, 1998.
DOI : 10.1109/50.664066

]. K. Spaulding and M. Morris, Achromatic waveguide input/output coupler design, Applied Optics, vol.30, issue.9, pp.1096-1112, 1991.
DOI : 10.1364/AO.30.001096

]. K. Spaulding and M. Morris, Achromatic waveguide couplers, Journal of Lightwave Technology, vol.10, issue.10, pp.1513-1518, 1992.
DOI : 10.1109/50.166797

]. T. Strasser, M. C. Gupta-]-k, J. L. Robin, A. Reverchon, L. Brignon et al., Grating coupler dispersion compensation with a surface-relief reflection grating, Conference on Lasers and Electro-Optics/International Quantum Electronics Conference, pp.3220-3226, 1994.
DOI : 10.1364/AO.33.003220

. Razeghi, AlGaN ultraviolet photoconductors grown on sapphire, Applied Physics Letters, vol.68, pp.2100-2101, 1996.

J. Renucci, . Frandon-]-g, J. L. Mazzeo, J. Y. Reverchon, A. Duboz et al., An AlGaN Based Linear Array for UV Solar Blind Imaging from 240 nm to 280 nm, Journal of Applied Physics IEEE-Sensors-Journal, vol.83, issue.64, pp.957-63, 1379.

]. F. Omnès, N. Marenco, B. Beaumont, P. De-mierry, E. Monroy et al., Metalorganic vapour-phase epitaxy grown AlGaN materials for visible-blind ultraviolet photodetector applications AlGaN-based focal plane arrays for selective UV imaging at 310nm and 280nm and route toward deep UV imaging, Journal of Applied Physics Proc. of SPIE N°, vol.86, issue.5286, pp.6744-94, 1999.

E. Truffer, J. Costard, E. Brault, J. Frayssinet, . Duboz et al., Detector for astrophysics, EDP Science, vol.37, 2008.

H. Benisty, R. Stanley, and M. Maier, Method of source terms for dipole emission modification in modes of arbitrary planar structures, Journal of the Optical Society of America A, vol.15, issue.5, pp.1192-1201, 1998.
DOI : 10.1364/JOSAA.15.001192

D. Cassio and J. P. Waller, Modification of Methionyl-tRNA Synthetase by Proteolytic Cleavage and Properties of the Trypsin-Modified Enzyme, European Journal of Biochemistry, vol.228, issue.2, pp.283-300, 1971.
DOI : 10.1016/0003-2697(69)90123-7

S. C. Gill and P. H. Von-hippel, Calculation of protein extinction coefficients from amino acid sequence data, Analytical Biochemistry, vol.182, issue.2, pp.319-326, 1989.
DOI : 10.1016/0003-2697(89)90602-7

P. H. Hirel, F. Lévêque, P. Mellot, F. Dardel, M. Panvert et al., Genetic engineering of methionyl-tRNA synthetase: in vitro regeneration of an active synthetase by proteolytic cleavage of a methionyl-tRNA synthetase-??-galactosidase chimeric protein, Biochimie, vol.70, issue.6, pp.773-782, 1988.
DOI : 10.1016/0300-9084(88)90107-1

G. Maezzo, J. L. Reverchon, J. Y. Duboz, and A. Dussaigne, AlGaN-Based Linear Array for UV Solar-Blind Imaging From 240 to 280 nm, IEEE Sensors Journal, vol.6, issue.4, pp.957-963, 2006.
DOI : 10.1109/JSEN.2006.877951

Y. Mechulam, E. Schmitt, L. Maveyraud, C. Zelwer, O. Nureki et al., Crystal structure of Escherichia coli methionyl-tRNA synthetase highlights species-specific features, Journal of Molecular Biology, vol.294, issue.5, pp.1287-1297, 1999.
DOI : 10.1006/jmbi.1999.3339
URL : https://hal.archives-ouvertes.fr/hal-00841066

P. Mellot, Y. Mechulam, D. Lecorre, S. Blanquet, and G. Fayat, Identification of an amino acid region supporting specific methionyl-tRNA synthetase: tRNA recognition, Journal of Molecular Biology, vol.208, issue.3, pp.429-443, 1989.
DOI : 10.1016/0022-2836(89)90507-X

B. D. Murphy, Fundamentals of Light Microscopy and Electronic Imaging, 2001.
DOI : 10.1002/9781118382905

C. N. Pace, F. Vajdos, L. Fee, G. Grimsley, and T. Gray, How to measure and predict the molar absorption coefficient of a protein, Protein Science, vol.33, issue.11, pp.2411-2423, 1995.
DOI : 10.1002/pro.5560041120

A. W. Peterson, R. J. Heaton, and R. M. Georgiadis, The effect of surface probe density on DNA hybridization, Nucleic Acids Research, vol.29, issue.24, pp.5163-5168, 2001.
DOI : 10.1093/nar/29.24.5163

B. O. Seraphin and N. Bottka, Franz-Keldysh Effect of the Refractive Index in Semiconductors, which turns out to be of the form (?l)(1 + ? R), pp.560-564, 1965.
DOI : 10.1103/PhysRev.139.A560

. Benisty, Eq. (17) with r2 =0,t2 = 1) The squared modulus of the total reads R + ? R(?l)(1 + ? R) 2 to first order in absorption. The relative change is thus as indicated. To our knowledge, only needlessly sophisticated versions of this basic physics exist in the literature Handbook of Optical Constants of Solids, pp.369-406, 1985.

E. A. Smith and R. M. Corn, Surface Plasmon Resonance Imaging as a Tool to Monitor Biomolecular Interactions in an Array Based Format, Applied Spectroscopy, vol.57, issue.11, pp.320-332, 2003.
DOI : 10.1366/000370203322554446

D. Stroud, Superlattice Microstruct, pp.567-573, 1998.

D. L. Windt, IMD???Software for modeling the optical properties of multilayer films, Computers in Physics, vol.12, issue.4, pp.360-370, 1998.
DOI : 10.1063/1.168689