I. G. Il-'chenko, O. G. Morgunov, A. P. Chernyavskaya, and . Sokolov, Biosynthesis of citric and isocitric acids from ethanol by mutant Yarrowia lipolytica N 1 under continuous cultivation, Appl Microbiol Biotechnol, vol.59, pp.493-500, 2002.

P. Fournier, L. Guyaneux, M. Chasles, and C. Gaillardin, Scarcity ofars sequences isolated in a morphogenesis mutant of the yeastYarrowia lipolytica, Yeast, vol.14, issue.1, pp.25-36, 1991.
DOI : 10.1002/yea.320070104

D. A. Freeman and M. Ascoli, Studies on the source of cholesterol used for steroid biosynthesis in cultured Leydig tumor cells, J Biol Chem, vol.257, pp.14231-14239, 1982.

S. Fukui and A. Tanaka, Metabolism of alkanes by yeasts, Adv. Biochem. Eng, vol.19, pp.217-237, 1981.
DOI : 10.1007/3-540-10464-X_19

C. Gaillardin and A. M. Ribet, LEU2 directed expression of ?-galactosidase activity and phleomycin resistance in Yarrowia lipolytica, Current Genetics, vol.76, issue.5, pp.369-75, 1987.
DOI : 10.1007/BF00378179

C. Gaillardin, A. M. Ribet, and H. Heslot, Integrative transformation of the yeast Yarrowia lipolytica, Current Genetics, vol.80, issue.1, pp.49-58, 1985.
DOI : 10.1007/BF00418493

D. Galluhn and T. Langer, Reversible Assembly of the ATP-binding Cassette Transporter Mdl1 with the F1F0-ATP Synthase in Mitochondria, Journal of Biological Chemistry, vol.279, issue.37, pp.38338-38383, 2004.
DOI : 10.1074/jbc.M405871200

J. Gartner, Disorders related to peroxisomal membranes, Journal of Inherited Metabolic Disease, vol.23, issue.3, pp.264-72, 2000.
DOI : 10.1023/A:1005636113499

P. O. Botstein and . Brown, Genomic expression programs in the response of yeast cells to environmental changes, Mol Biol Cell, vol.11, pp.4241-57, 2000.

S. J. Erdmann and . Gould, Molecular characterization of Saccharomyces cerevisiae Delta3, Delta2-enoyl-CoA isomerase, J Biol Chem, vol.273, pp.33184-91, 1998.

M. Gilewicz, M. Zacek, J. C. Bertrand, and E. Azoulay, grown on alkanes, Canadian Journal of Microbiology, vol.25, issue.2, pp.201-207, 1979.
DOI : 10.1139/m79-031

C. O. Gill and C. Ratledge, Effect of n-alkanes on the transport of glucose in Candida sp. strain 107, Biochem J, vol.127, pp.59-60, 1972.

C. I. Gonzalez and C. E. Martin, Fatty acid-responsive control of mRNA stability. Unsaturated fatty acid-induced degradation of the Saccharomyces OLE1 transcript, J Biol Chem, vol.271, pp.25801-25810, 1996.

. Suzzi, Variability of the lipolytic activity in Yarrowia lipolytica and its dependence on environmental conditions, Int J Food Microbiol, vol.69, pp.79-89, 2001.

A. Gurvitz, H. Hamilton, A. Ruis, and . Hartig, Peroxisomal Degradation of trans-Unsaturated Fatty Acids in the Yeast Saccharomyces cerevisiae, Journal of Biological Chemistry, vol.276, issue.2, pp.895-903, 2001.
DOI : 10.1074/jbc.M003305200

J. K. Ruis, H. Hiltunen, and . Rottensteiner, Peroxisomal Delta3-cis-Delta2-trans- enoyl-CoA isomerase encoded by ECI1 is required for growth of the yeast Saccharomyces cerevisiae on unsaturated fatty acids, J Biol Chem, vol.273, pp.31366-74, 1998.

. Hiltunen, Alternatives to the isomerase-dependent pathway for the beta-oxidation of oleic acid are dispensable in Saccharomyces cerevisiae. Identification of YOR180c/DCI1 encoding peroxisomal delta(3,5)-delta(2,4)-dienoyl-CoA isomerase, J Biol Chem, vol.274, pp.24514-24535, 1999.

W. Dawes and B. Hamilton, The Saccharomyces cerevisiae peroxisomal, 1997.

J. T. Gwynne and J. F. Strauss, The Role of Lipoproteins in Steroidogenesis and Cholesterol Metabolism in Steroidogenic Glands*, Endocrine Reviews, vol.3, issue.3, pp.299-329, 1982.
DOI : 10.1210/edrv-3-3-299

A. Haid and M. Suissa, [13] Immunochemical identification of membrane proteins after sodium dodecyl sulfate???polyacrylamide gel electrophoresis, Methods Enzymol, vol.96, pp.192-205, 1983.
DOI : 10.1016/S0076-6879(83)96017-2

J. A. Hamilton, Fatty acid transport: difficult or easy?, J Lipid Res, vol.39, pp.467-81, 1998.

L. Oriedo, M. Rasochova, B. Subramanian, E. L. Miller, and . White, Development of a plant viral-vector-based gene expression assay for the screening of yeast cytochrome p450 monooxygenases, Assay Drug Dev Technol, vol.1, pp.147-60, 2003.

M. Hasslacher, A. S. Ivessa, F. Paltauf, and S. D. Kohlwein, Acetyl-CoA carboxylase from yeast is an essential enzyme and is regulated by factors that control phospholipid metabolism, J Biol Chem, vol.268, pp.10946-52, 1993.

K. Hellauer, B. Akache, S. Macpherson, E. Sirard, and B. Turcotte, Zinc Cluster Protein Rdr1p Is a Transcriptional Repressor of thePDR5 Gene Encoding a Multidrug Transporter, Journal of Biological Chemistry, vol.277, issue.20, pp.17671-17677, 2002.
DOI : 10.1074/jbc.M201637200

B. Henke, W. Girzalsky, V. Berteaux-lecellier, and R. Erdmann, IDP3 Encodes a Peroxisomal NADP-dependent Isocitrate Dehydrogenase Required for the beta -Oxidation of Unsaturated Fatty Acids, Journal of Biological Chemistry, vol.273, issue.6, pp.3702-3713, 1998.
DOI : 10.1074/jbc.273.6.3702

K. W. Henry, J. T. Nickels, and T. D. Edlind, Upregulation of ERG Genes in Candida Species by Azoles and Other Sterol Biosynthesis Inhibitors, Antimicrobial Agents and Chemotherapy, vol.44, issue.10, pp.2693-700, 2000.
DOI : 10.1128/AAC.44.10.2693-2700.2000

E. H. Hettema and H. F. Tabak, Transport of fatty acids and metabolites across the peroxisomal membrane, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1486, issue.1, pp.18-27, 2000.
DOI : 10.1016/S1388-1981(00)00045-7

R. J. Rodrigues-pousada, H. F. Wanders, and . Tabak, The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae, Embo J, vol.15, pp.3813-3835, 1996.

I. Hikkel, A. Lucau-danila, T. Delaveau, P. Marc, F. Devaux et al., A General Strategy to Uncover Transcription Factor Properties Identifies a New Regulator of Drug Resistance in Yeast, Journal of Biological Chemistry, vol.278, issue.13, pp.11427-11459, 2003.
DOI : 10.1074/jbc.M208549200

T. Hoppe, K. Matuschewski, M. Rape, S. Schlenker, H. D. Ulrich et al., Activation of a Membrane-Bound Transcription Factor by Regulated Ubiquitin/Proteasome-Dependent Processing, Cell, vol.102, issue.5, pp.577-86, 2000.
DOI : 10.1016/S0092-8674(00)00080-5

J. C. Igual, E. Matallana, C. Gonzalez-bosch, L. Franco, and J. E. Perez-ortin, A new glucose-repressible gene identified from the analysis of chromatin structure in deletion mutants of yeastSUC2 locus, Yeast, vol.286, issue.4, pp.379-89, 1991.
DOI : 10.1002/yea.320070408

T. Iida, A. Ohta, and M. Takagi, Cloning and characterization of an n???alkane???inducible cytochrome P450 gene essential for n???decane assimilation by Yarrowia lipolytica, Yeast, vol.14, issue.15, pp.1387-1397, 1998.
DOI : 10.1002/(SICI)1097-0061(199811)14:15<1387::AID-YEA333>3.3.CO;2-D

T. Iida, T. Sumita, A. Ohta, and M. Takagi, The cytochrome P450ALK multigene family of ann-alkane-assimilating yeast,Yarrowia lipolytica: cloning and characterization of genes coding for new CYP52 family members, Yeast, vol.224, issue.12, pp.1077-1087, 2000.
DOI : 10.1002/1097-0061(20000915)16:12<1077::AID-YEA601>3.0.CO;2-K

B. Jank, B. Habermann, R. J. Schweyen, and T. A. Link, PMP47, a peroxisomal homologue of mitochondrial solute carrier proteins, Trends Biochem Sci, vol.18, pp.427-435, 1993.

D. R. Johnson, L. J. Knoll, D. E. Levin, and J. I. Gordon, Saccharomyces cerevisiae contains four fatty acid activation (FAA) genes: an assessment of their role in regulating protein N- myristoylation and cellular lipid metabolism, The Journal of Cell Biology, vol.127, issue.3, pp.751-62, 1994.
DOI : 10.1083/jcb.127.3.751

H. Jungwirth and K. Kuchler, Yeast ABC transporters - A tale of sex, stress, drugs and aging, FEBS Letters, vol.400, issue.4, pp.1131-1139, 2006.
DOI : 10.1016/j.febslet.2005.12.050

P. Piper, Y. Mahe, S. Thompson, R. Pandjaitan, C. Holyoak et al., The Pdr12 ABC transporter is required for the development of weak organic acid resistance in yeast, The EMBO Journal, vol.17, issue.15, pp.4257-65, 1998.
DOI : 10.1093/emboj/17.15.4257

R. K. Plemper, R. Egner, K. Kuchler, and D. H. Wolf, Endoplasmic Reticulum Degradation of a Mutated ATP-binding Cassette Transporter Pdr5 Proceeds in a Concerted Action of Sec61 and the Proteasome, Journal of Biological Chemistry, vol.273, issue.49, pp.32848-56, 1998.
DOI : 10.1074/jbc.273.49.32848

A. Pohl, P. F. Devaux, and A. Herrmann, Function of prokaryotic and eukaryotic ABC proteins in lipid transport, Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, vol.1733, issue.1, pp.29-52, 2005.
DOI : 10.1016/j.bbalip.2004.12.007

R. Prasad, P. De-wergifosse, A. Goffeau, and E. Balzi, Molecular cloning and characterization of a novel gene of Candida albicans, CDR1, conferring multiple resistance to drugs and antifungals, Current Genetics, vol.225, issue.4, pp.320-329, 1995.
DOI : 10.1007/BF00352101

R. Prasad, S. L. Panwar, and S. , Drug resistance in yeasts ??? an emerging scenario, Adv Microb Physiol, vol.46, pp.155-201, 2002.
DOI : 10.1016/S0065-2911(02)46004-3

C. Ratledge, Yeasts, moulds, algae and bacteria as sources of lipids, pp.235-291, 1994.
DOI : 10.1007/978-1-4615-2109-9_9

S. Kamel and Y. Kakuda, Technological advances in improved and alternative sources of lipids. Blackie academic and professional

C. Ratlege and K. Tan, Oils and fats: production, degradation and utilization by yeasts. Yeast biotechnology and biocatalysis, pp.223-254, 1990.

J. R. Riordan, ASSEMBLY OF FUNCTIONAL CFTR CHLORIDE CHANNELS, Annual Review of Physiology, vol.67, issue.1, pp.701-718, 2005.
DOI : 10.1146/annurev.physiol.67.032003.154107

W. B. Rizzo, Z. Lin, and G. Carney, Fatty aldehyde dehydrogenase: genomic structure, expression and mutation analysis in Sj??gren???Larsson syndrome, Chemico-Biological Interactions, vol.130, issue.132, pp.297-307, 2001.
DOI : 10.1016/S0009-2797(00)00273-8

. Amaral, Yeast activator proteins and stress response: an overview, FEBS Lett, 2004.

T. M. Rose, E. R. Schultz, and G. J. Todaro, Molecular cloning of the gene for the yeast homolog (ACB) of diazepam binding inhibitor/endozepine/acyl-CoA-binding protein., Proceedings of the National Academy of Sciences, vol.89, issue.23, 1992.
DOI : 10.1073/pnas.89.23.11287

. Ruis, Pip2p: a transcriptional regulator of peroxisome proliferation in the yeast Saccharomyces cerevisiae, Embo J, vol.15, pp.2924-2958, 1996.

. Gurvitz, The peroxisomal transporter gene ANT1 is regulated by a deviant oleate response element (ORE): characterization of the signal for fatty acid induction, Biochem. J, vol.365, pp.109-117, 2002.

T. Sakaki and K. Inouye, Practical application of mammalian cytochrome P450, Journal of Bioscience and Bioengineering, vol.90, issue.6, pp.583-90, 2000.
DOI : 10.1016/S1389-1723(00)90001-X

A. Saleh, V. Lang, R. Cook, and C. J. Brandl, Identification of Native Complexes Containing the Yeast Coactivator/Repressor Proteins NGG1/ADA3 and ADA2, Journal of Biological Chemistry, vol.272, issue.9, pp.5571-5579, 1997.
DOI : 10.1074/jbc.272.9.5571

H. Lenman, S. Ronne, and . Stymne, Storage lipid synthesis is non-essential in yeast, J Biol Chem, vol.277, pp.6478-82, 2002.

. Takaki, Bioemulsifier production in batch culture using glucose as carbon source by Candida lipolytica, Appl Biochem Biotechnol, vol.95, pp.59-67, 2001.

B. Sauer, Functional expression of the cre-lox site-specific recombination system in the yeast Saccharomyces cerevisiae., Molecular and Cellular Biology, vol.7, issue.6, pp.2087-96, 1987.
DOI : 10.1128/MCB.7.6.2087

J. E. Schaffer and H. F. Lodish, Expression cloning and characterization of a novel adipocyte long chain fatty acid transport protein, Cell, vol.79, issue.3, pp.427-463, 1994.
DOI : 10.1016/0092-8674(94)90252-6

U. Scheller, T. Zimmer, D. Becher, F. Schauer, and W. H. Schunck, Oxygenation Cascade in Conversion of n-Alkanes to alpha ,omega -Dioic Acids Catalyzed by Cytochrome P450 52A3, Journal of Biological Chemistry, vol.273, issue.49, pp.32528-32562, 1998.
DOI : 10.1074/jbc.273.49.32528

U. Scheller, T. Zimmer, E. Kargel, and W. Schunck, Characterization of, 1996.

J. Schindler, F. Meusdoerffer, and H. Giesel-bühler, Microbial production in industrial chemicals: basic features of dicarboxylic acid production by yeast (Germ), Forum Mikrobiol, vol.5, pp.274-281, 1990.

J. Kristiansen and . Knudsen, Disruption of the gene encoding the acyl-CoA-binding protein (ACB1) perturbs acyl-CoA metabolism in Saccharomyces cerevisiae, J Biol Chem, vol.271, pp.22514-22535, 1996.

N. Schmid-berger, B. Schmid, and G. Barth, Ylt1, a highly repetitive retrotransposon in the genome of the dimorphic fungus Yarrowia lipolytica., Journal of Bacteriology, vol.176, issue.9, pp.2477-82, 1994.
DOI : 10.1128/jb.176.9.2477-2482.1994

M. S. Smit, M. M. Mokgoro, E. Setati, and J. M. Nicaud, ??,??-Dicarboxylic acid accumulation by acyl-CoA oxidase deficient mutants of Yarrowia lipolytica, Biotechnology Letters, vol.181, issue.12, pp.859-64, 2005.
DOI : 10.1007/s10529-005-6719-1

B. T. Smith, T. K. Sengupta, and I. Singh, Intraperoxisomal Localization of Very-Long-Chain Fatty Acyl-CoA Synthetase: Implication in X-Adrenoleukodystrophy, Experimental Cell Research, vol.254, issue.2, pp.309-329, 2000.
DOI : 10.1006/excr.1999.4757

D. Sorger, K. Athenstaedt, C. Hrastnik, and G. Daum, A Yeast Strain Lacking Lipid Particles Bears a Defect in Ergosterol Formation, Journal of Biological Chemistry, vol.279, issue.30, 2004.
DOI : 10.1074/jbc.M403251200

D. Sorger and G. Daum, Synthesis of Triacylglycerols by the Acyl-Coenzyme A:Diacyl-Glycerol Acyltransferase Dga1p in Lipid Particles of the Yeast Saccharomyces cerevisiae, Journal of Bacteriology, vol.184, issue.2, pp.519-543, 2002.
DOI : 10.1128/JB.184.2.519-524.2002

D. Sorger and G. Daum, Triacylglycerol biosynthesis in yeast, Applied Microbiology and Biotechnology, vol.267, issue.4, pp.289-99, 2003.
DOI : 10.1007/s00253-002-1212-4

S. J. Steinberg, S. J. Wang, D. G. Kim, S. J. Mihalik, and P. A. Watkins, Human Very-Long-Chain Acyl-CoA Synthetase: Cloning, Topography, and Relevance to Branched-Chain Fatty Acid Metabolism, Biochemical and Biophysical Research Communications, vol.257, issue.2, pp.615-636, 1999.
DOI : 10.1006/bbrc.1999.0510

L. C. Stewart and M. P. Yaffe, A role for unsaturated fatty acids in mitochondrial movement and inheritance, The Journal of Cell Biology, vol.115, issue.5, pp.1249-57, 1991.
DOI : 10.1083/jcb.115.5.1249

J. Storch, Diversity of fatty acid-binding protein structure and function: studies with fluorescent ligands, Molecular and Cellular Biochemistry, vol.1113, issue.1-2, pp.45-53, 1993.
DOI : 10.1007/BF01076474

J. E. Stukey, V. M. Mcdonough, and C. E. Martin, Isolation and characterization of OLE1, a gene affecting fatty acid desaturation from Saccharomyces cerevisiae, J Biol Chem, vol.264, pp.16537-16581, 1989.

J. E. Stukey, V. M. Mcdonough, and C. E. Martin, The OLE1 gene of Saccharomyces cerevisiae encodes the delta 9 fatty acid desaturase and can be functionally replaced by the rat stearoyl-CoA desaturase gene, J Biol Chem, vol.265, pp.20144-20153, 1990.

T. Sumita, T. Iida, S. Yamagami, H. Horiuchi, M. Takagi et al., YlALK1 encoding the cytochrome P450ALK1 in Yarrowia lipolytica is transcriptionally induced by n-alkane through two distinct cis-elements on its promoter, Biochemical and Biophysical Research Communications, vol.294, issue.5, pp.1071-1078, 2002.
DOI : 10.1016/S0006-291X(02)00607-1

E. E. Swartzman, M. N. Viswanathan, and J. Thorner, The PAL1 gene product is a peroxisomal ATP-binding cassette transporter in the yeast Saccharomyces cerevisiae, The Journal of Cell Biology, vol.132, issue.4, pp.549-63, 1996.
DOI : 10.1083/jcb.132.4.549

H. R. Tabak, R. J. Waterham, and . Wanders, Identification of a peroxisomal ATP carrier required for medium-chain fatty acid beta-oxidation and normal peroxisome proliferation in Saccharomyces cerevisiae, Mol Cell Biol, vol.21, pp.4321-4330, 2001.

C. W. Van-roermund, Y. Elgersma, N. Singh, R. J. Wanders, and H. F. Tabak, The membrane of peroxisomes in Saccharomyces cerevisiae is impermeable to NAD(H) and acetyl-CoA under in vivo conditions, Embo J, vol.14, pp.3480-3486, 1995.

J. Wanders, Peroxisomal beta-oxidation of polyunsaturated fatty acids in Saccharomyces cerevisiae: isocitrate dehydrogenase provides NADPH for reduction of double bonds at even positions, Embo J, vol.17, pp.677-87, 1998.

. Hettema, Pex11p plays a primary role in medium-chain fatty acid oxidation, a process that affects peroxisome number and size in Saccharomyces cerevisiae, J Cell Biol, vol.150, pp.489-98, 2000.

M. Vance-harrop, N. Gusmao, and G. M. Campos-takaki, New bioemulsifiers produced by Candida lipolytica using D-glucose and babassu oil as carbon sources, Brazilian Journal of Microbiology, vol.34, issue.2, pp.120-123, 2003.
DOI : 10.1590/S1517-83822003000200006

S. Vanhanen, M. West, J. T. Kroon, N. Lindner, J. Casey et al., A Consensus Sequence for Long-chain Fatty-acid Alcohol Oxidases from Candida Identifies a Family of Genes Involved in Lipid ??-Oxidation in Yeast with Homologues in Plants and Bacteria, Journal of Biological Chemistry, vol.275, issue.6, pp.4445-52, 2000.
DOI : 10.1074/jbc.275.6.4445

. Fournier, An origin of replication and a centromere are both needed to establish a replicative plasmid in the yeast Yarrowia lipolytica, Mol Cell Biol, vol.17, pp.1995-2004, 1997.

. Nicaud, Evaluation of acyl coenzyme A oxidase (Aox) isozyme function in the nalkane-assimilating yeast Yarrowia lipolytica, J. Bacteriol, vol.181, pp.5140-5148, 1999.

T. Wang, Y. Luo, and G. M. Small, The POX1 gene encoding peroxisomal acyl-CoA oxidase in Saccharomyces cerevisiae is under the control of multiple regulatory elements, J Biol Chem, vol.269, pp.24480-24485, 1994.

P. A. Watkins, J. F. Lu, L. T. Braiterman, S. J. Steinberg, and K. D. Smith, Disruption of a Yeast Very-Long-Chain Acyl-CoA Synthetase Gene Simulates the Cellular Phenotype of X-Linked Adrenoleukodystrophy, Cell Biochemistry and Biophysics, vol.32, issue.1-3, pp.333-340, 2000.
DOI : 10.1385/CBB:32:1-3:333

C. D. Albuquerque, A. M. Filetti, and G. M. Campos-takaki, with response surface method, Canadian Journal of Microbiology, vol.52, issue.6, pp.575-583, 2006.
DOI : 10.1139/w06-002

K. Athenstaedt, P. Jolivet, C. Boulard, M. Zivy, L. Negroni et al., Lipid particle composition of the yeastYarrowia lipolytica depends on the carbon source, PROTEOMICS, vol.279, issue.5, pp.1450-1459, 2006.
DOI : 10.1002/pmic.200500339

N. Bati, E. G. Hammond, and B. A. Glatz, Biomodification of fats and oils: Trials withCandida lipolytica, Journal of the American Oil Chemists??? Society, vol.4, issue.11, pp.1743-1746, 1984.
DOI : 10.1007/BF02582139

F. Bigey, K. Tuery, D. Bougard, J. M. Nicaud, and G. Moulin, Identification of a triacylglycerol lipase gene family inCandida deformans: molecular cloning and functional expression, Yeast, vol.28, issue.3, pp.233-248, 2003.
DOI : 10.1002/yea.958

A. L. Botes and J. Lotter, WO Patent Application, pp.100587-100589, 2005.

A. L. Botes, J. Lotter, and M. Labuschagne, WO Patent Application, pp.100578-100580, 2005.

A. L. Botes, J. Lotter, M. , L. Mitra, and R. K. , WO Patent Application, pp.100569-100571, 2005.

A. L. Botes, J. Lotter, O. H. Rhode, and A. Botha, Interspecies differences in the enantioselectivity of epoxide hydrolases in Cryptococcus laurentii (Kufferath) C.E. Skinner and Cryptococcus podzolicus (Bab???jeva & Reshetova) Golubev, Systematic and Applied Microbiology, vol.28, issue.1, pp.27-33, 2005.
DOI : 10.1016/j.syapm.2004.10.003

G. Butler, C. Kenny, A. Fagan, C. Kurischko, C. Gaillardin et al., Evolution of the MAT locus and its Ho endonuclease in yeast species, Proceedings of the National Academy of Sciences, vol.46, issue.2, pp.1632-1637, 2004.
DOI : 10.1099/00207713-46-2-542

S. Casaregola, C. Neuveglise, E. Bon, and C. Gaillardin, Ylli, a Non-LTR Retrotransposon L1 Family in the Dimorphic Yeast Yarrowia lipolytica, Molecular Biology and Evolution, vol.19, issue.5, pp.664-677, 2002.
DOI : 10.1093/oxfordjournals.molbev.a004125

M. Certick and S. Shimizu, Agro food indistry hi-Tech, pp.26-32, 1999.

O. G. Chernyavskaya, N. V. Shishkanova, A. P. Il-'chenko, and T. V. Finogenova, Synthesis of ??-ketoglutaric acid by Yarrowia lipolytica yeast grown on ethanol, Applied Microbiology and Biotechnology, vol.53, issue.2, pp.152-158, 2000.
DOI : 10.1007/s002530050002

H. G. Damude, H. Zhang, L. Farrall, K. G. Ripp, J. F. Tomb et al., Identification of bifunctional ??12/??3 fatty acid desaturases for improving the ratio of ??3 to ??6 fatty acids in microbes and plants, Proceedings of the National Academy of Sciences, vol.261, issue.3, pp.9446-9451, 2006.
DOI : 10.1007/BF02532690

A. Dominguez, E. Ferminan, and C. Gaillardin, <i>Yarrowia lipolytica</i>: An Organism Amenable to Genetic Manipulation as a Model for Analyzing Dimorphism in Fungi, Contrib Microbiol, vol.5, pp.151-172, 2000.
DOI : 10.1159/000060349

B. Dujon, D. Sherman, G. Fischer, P. Durrens, S. Casaregola et al., Genome evolution in yeasts, Nature, vol.316, issue.6995, pp.35-44, 2004.
DOI : 10.1093/nar/gkg056
URL : https://hal.archives-ouvertes.fr/hal-00104411

W. Eschenfeldt, Y. Zhang, H. Samaha, L. Stols, L. Eirich et al., Transformation of Fatty Acids Catalyzed by Cytochrome P450 Monooxygenase Enzymes of Candida tropicalis, Applied and Environmental Microbiology, vol.69, issue.10, pp.5992-5999, 2003.
DOI : 10.1128/AEM.69.10.5992-5999.2003

G. Fantin, M. Fogagnolo, P. P. Giovannini, A. Medici, P. Pedrini et al., Anti-Prelog microbial reduction of prochiral carbonyl compounds, Tetrahedron, vol.52, issue.10, pp.3547-3552, 1996.
DOI : 10.1016/0040-4020(96)00031-2

G. Fantin, M. Fogagnolo, A. Guerrini, A. Medici, P. Pedrini et al., Enantioselective hydrolyses with Yarrowia lipolytica: a versatile strain for esters, enol esters, epoxides, and lactones, Tetrahedron: Asymmetry, vol.12, issue.19, pp.2709-2713, 2001.
DOI : 10.1016/S0957-4166(01)00463-3

G. Fantin, M. Fogagnolo, A. Medici, P. Pedrini, and S. Fontana, Kinetic resolution of racemic secondary alcohols via oxidation with Yarrowia lipolytica strains, Tetrahedron: Asymmetry, vol.11, issue.11, pp.2367-2373, 2000.
DOI : 10.1016/S0957-4166(00)00185-3

P. Fickers, P. H. Benetti, Y. Wache, A. Marty, S. Mauersberger et al., Hydrophobic substrate utilisation by the yeast , and its potential applications, FEMS Yeast Research, vol.5, issue.6-7, pp.527-543, 2005.
DOI : 10.1016/j.femsyr.2004.09.004
URL : https://hal.archives-ouvertes.fr/hal-00368201

P. Fickers, F. Fudalej, L. Dall, M. T. Casaregola, S. Gaillardin et al., Identification and characterisation of LIP7 and LIP8 genes encoding two extracellular triacylglycerol lipases in the yeast Yarrowia lipolytica, Fungal Genetics and Biology, vol.42, issue.3, pp.264-274, 2005.
DOI : 10.1016/j.fgb.2004.12.003

P. Fickers, L. Dall, M. T. Gaillardin, C. Thonart, P. Nicaud et al., New disruption cassettes for rapid gene disruption and marker rescue in the yeast Yarrowia lipolytica, Journal of Microbiological Methods, vol.55, issue.3, pp.727-737, 2003.
DOI : 10.1016/j.mimet.2003.07.003

D. Guieysse, G. Sandoval, L. Faure, J. Nicaud, P. Monsan et al., New efficient lipase from Yarrowia lipolytica for the resolution of 2-bromo-arylacetic acid esters, Tetrahedron: Asymmetry, vol.15, issue.22, pp.3539-3543, 2004.
DOI : 10.1016/j.tetasy.2004.09.008

K. Hanley, L. V. Nguyen, F. Khan, G. P. Pogue, F. Vojdani et al., Development of a Plant Viral-Vector-Based Gene Expression Assay for the Screening of Yeast Cytochrome P450 Monooxygenases, ASSAY and Drug Development Technologies, vol.1, issue.supplement 2, pp.147-160, 2003.
DOI : 10.1089/154065803321537863

X. He, B. Chen, and T. Tan, Enzymatic synthesis of 2-ethylhexyl esters of fatty acids by immobilized lipase from Candida sp. 99???125, Journal of Molecular Catalysis B: Enzymatic, vol.18, issue.4-6, pp.333-339, 2002.
DOI : 10.1016/S1381-1177(02)00114-5

D. Holzschu, F. Chandler, L. Ajello, and D. Ahearn, Evaluation of industrial yeasts for pathogenicity, Medical Mycology, vol.17, issue.1, pp.71-78, 1979.
DOI : 10.1080/00362177985380091

T. Iida, A. Ohta, and M. Takagi, Cloning and characterization of ann-alkane-inducible cytochrome P450 gene essential forn-decane assimilation byYarrowia lipolytica, Yeast, vol.17, issue.15, pp.1387-1397, 1998.
DOI : 10.1002/(SICI)1097-0061(199811)14:15<1387::AID-YEA333>3.0.CO;2-M

T. Juretzek, L. Dall, M. Mauersberger, S. Gaillardin, C. Barth et al., Vectors for gene expression and amplification in the yeastYarrowia lipolytica, Yeast, vol.184, issue.2, pp.97-113, 2001.
DOI : 10.1002/1097-0061(20010130)18:2<97::AID-YEA652>3.0.CO;2-U

T. Juretzek, H. Wang, J. Nicaud, S. Mauersberger, and G. Barth, Comparison of promoters suitable for regulated overexpression of ??-galactosidase in the alkane-utilizing yeastYarrowia lipolytica, Biotechnology and Bioprocess Engineering, vol.25, issue.5, pp.320-326, 2000.
DOI : 10.1007/BF02942206

K. C. Keiser, K. S. Brandt, G. M. Silver, and N. Wisnewski, Cloning, partial purification and in vivo developmental profile of expression of the juvenile hormone epoxide hydrolase ofCtenocephalides felis, Archives of Insect Biochemistry and Physiology, vol.220, issue.4, pp.191-206, 2002.
DOI : 10.1002/arch.10044

C. Kurtzman and J. Fell, The yeast :a taxonomy study, Elsvier Siences, 1998.

C. P. Kurtzman, New species and a new combination in the Hyphopichia and Yarrowia yeast clades, Antonie van Leeuwenhoek, vol.42, issue.2, pp.121-130, 2005.
DOI : 10.1007/s10482-005-2495-0

F. Lagos, J. Carballeira, J. L. Bermudez, E. Alvarez, and J. Sinisterra, Highly stereoselective reduction of haloketones using three new yeasts: application to the synthesis of (S)-adrenergic ??-blockers related to propranolol, Tetrahedron: Asymmetry, vol.15, issue.5, pp.763-770, 2004.
DOI : 10.1016/j.tetasy.2004.01.024

L. Cao and J. L. , Enantioconvergent production of (R)-1-phenyl-1,2-ethanediol from styrene oxide by combining theSolanum tuberosum and an evolvedAgrobacterium radiobacter AD1 epoxide hydrolases, Biotechnology and Bioengineering, vol.6, issue.3, pp.522-529, 2006.
DOI : 10.1002/bit.20860

Y. S. Luo, J. M. Nicaud, P. P. Van-veldhoven, and T. Chardot, The acyl???CoA oxidases from the yeast Yarrowia lipolytica: characterization of Aox2p, Archives of Biochemistry and Biophysics, vol.407, issue.1, pp.32-38, 2002.
DOI : 10.1016/S0003-9861(02)00466-6

Y. S. Luo, H. J. Wang, K. V. Gopalan, D. K. Srivastava, J. M. Nicaud et al., Purification and Characterization of the Recombinant Form of Acyl CoA Oxidase 3 from the Yeast Yarrowia lipolytica, Archives of Biochemistry and Biophysics, vol.384, issue.1, pp.1-8, 2000.
DOI : 10.1006/abbi.2000.2079

C. Madzak, C. Gaillardin, and J. M. Beckerich, Heterologous protein expression and secretion in the non-conventional yeast Yarrowia lipolytica: a review, Journal of Biotechnology, vol.109, issue.1-2, pp.63-81, 2004.
DOI : 10.1016/j.jbiotec.2003.10.027

C. Madzak, J. Nicaud, and C. Gaillardin, In Production of recombinant proteins: microbial and eucaryotic expression systems, pp.163-189, 2005.

C. Marck, R. Kachouri-lafond, I. Lafontaine, E. Westhof, B. Dujon et al., The RNA polymerase III-dependent family of genes in hemiascomycetes: comparative RNomics, decoding strategies, transcription and evolutionary implications, Nucleic Acids Research, vol.34, issue.6, pp.1816-1835, 2006.
DOI : 10.1093/nar/gkl085
URL : https://hal.archives-ouvertes.fr/hal-00094338

K. Mlickova, E. Roux, K. Athenstaedt, S. Andrea, G. Daum et al., Lipid Accumulation, Lipid Body Formation, and Acyl Coenzyme A Oxidases of the Yeast Yarrowia lipolytica, Applied and Environmental Microbiology, vol.70, issue.7, pp.3918-3924, 2004.
DOI : 10.1128/AEM.70.7.3918-3924.2004

C. Neuveglise, F. Chalvet, P. Wincker, C. Gaillardin, and S. Casaregola, Mutator-Like Element in the Yeast Yarrowia lipolytica Displays Multiple Alternative Splicings, Eukaryotic Cell, vol.4, issue.3, pp.615-624, 2005.
DOI : 10.1128/EC.4.3.615-624.2005
URL : https://hal.archives-ouvertes.fr/hal-00101354

C. Neuveglise, H. Feldmann, E. Bon, C. Gaillardin, and S. Casaregola, Genomic Evolution of the Long Terminal Repeat Retrotransposons in Hemiascomycetous Yeasts, Genome Research, vol.12, issue.6, pp.930-943, 2002.
DOI : 10.1101/gr.219202

Y. Pagot, L. Clainche, A. Nicaud, J. M. Wache, Y. Belin et al., Peroxisomal ??-oxidation activities and ??-decalactone production by the yeast Yarrowia lipolytica, Applied Microbiology and Biotechnology, vol.49, issue.3, pp.295-300, 1998.
DOI : 10.1007/s002530051172
URL : https://hal.archives-ouvertes.fr/hal-00368241

S. Papanikolaou and G. Aggelis, Lipid production by Yarrowia lipolytica growing on industrial glycerol in a single-stage continuous culture, Bioresource Technology, vol.82, issue.1, pp.43-49, 2002.
DOI : 10.1016/S0960-8524(01)00149-3

S. Papanikolaou and G. Aggelis, Modeling Lipid Accumulation and Degradation in Yarrowia lipolytica Cultivated on Industrial Fats, Current Microbiology, vol.46, issue.6, pp.398-402, 2003.
DOI : 10.1007/s00284-002-3907-2

S. Papanikolaou and G. Aggelis, Selective uptake of fatty acids by the yeastYarrowia lipolytica, European Journal of Lipid Science and Technology, vol.105, issue.11, pp.651-655, 2003.
DOI : 10.1002/ejlt.200300858

S. Papanikolaou, L. Muniglia, I. Chevalot, G. Aggelis, and I. Marc, Accumulation of a Cocoa-Butter-Like Lipid by Yarrowia lipolytica Cultivated on Agro-Industrial Residues, Current Microbiology, vol.46, issue.2, pp.124-130, 2003.
DOI : 10.1007/s00284-002-3833-3

S. Picataggio, K. Deanda, and J. Mielenz, Determination of Candida tropicalis acyl coenzyme A oxidase isozyme function by sequential gene disruption., Molecular and Cellular Biology, vol.11, issue.9, pp.4333-4339, 1991.
DOI : 10.1128/MCB.11.9.4333

S. Picataggio, T. Rohrer, K. Deanda, D. Lanning, R. Reynolds et al., Metabolic Engineering of Candida Tropicalis for the Production of Long???Chain Dicarboxylic Acids, Bio/Technology, vol.83, issue.8, pp.894-898, 1992.
DOI : 10.1083/jcb.61.1.188

G. Pignede, H. Wang, F. Fudalej, C. Gaillardin, M. Seman et al., Characterization of an Extracellular Lipase Encoded by LIP2 in Yarrowia lipolytica, Journal of Bacteriology, vol.182, issue.10, pp.2802-2810, 2000.
DOI : 10.1128/JB.182.10.2802-2810.2000

G. Pignede, H. J. Wang, F. Fudalej, M. Seman, C. Gaillardin et al., Autocloning and Amplification of LIP2 in Yarrowia lipolytica, Applied and Environmental Microbiology, vol.66, issue.8, pp.3283-3289, 2000.
DOI : 10.1128/AEM.66.8.3283-3289.2000

C. Ratledge, Microorganisms for lipids, Acta Biotechnologica, vol.2, issue.2, pp.429-438, 1991.
DOI : 10.1002/abio.370110506

L. Sandager, M. H. Gustavsson, U. Stahl, A. Dahlqvist, E. Wiberg et al., Storage Lipid Synthesis Is Non-essential in Yeast, Journal of Biological Chemistry, vol.277, issue.8, pp.6478-6482, 2002.
DOI : 10.1074/jbc.M109109200

M. Sinigaglia, R. Lanciotti, and M. Guerzoni, strains in relation to isolation source, Canadian Journal of Microbiology, vol.40, issue.1, pp.54-59, 1994.
DOI : 10.1139/m94-008

Y. Wache, M. Aguedo, A. Choquet, I. L. Gatfield, J. M. Nicaud et al., Role of beta -Oxidation Enzymes in gamma -Decalactone Production by the Yeast Yarrowia lipolytica, Applied and Environmental Microbiology, vol.67, issue.12, pp.5700-5704, 2001.
DOI : 10.1128/AEM.67.12.5700-5704.2001
URL : https://hal.archives-ouvertes.fr/hal-00368231

Y. Wache, M. Aguedo, J. M. Nicaud, and J. M. Belin, Catabolism of hydroxyacids and biotechnological production of lactones by Yarrowia lipolytica, Applied Microbiology and Biotechnology, vol.273, issue.5-6, pp.393-404, 2003.
DOI : 10.1007/s00253-002-1207-1
URL : https://hal.archives-ouvertes.fr/hal-00368224

Y. Wache, C. Laroche, K. Bergmark, C. Moller-andersen, M. Aguedo et al., Involvement of Acyl Coenzyme A Oxidase Isozymes in Biotransformation of Methyl Ricinoleate into gamma -Decalactone by Yarrowia lipolytica, Applied and Environmental Microbiology, vol.66, issue.3, pp.1233-1236, 2000.
DOI : 10.1128/AEM.66.3.1233-1236.2000
URL : https://hal.archives-ouvertes.fr/hal-00368236

C. A. Weijers and J. A. De-bont, Epoxide hydrolases from yeasts and other sources: versatile tools in biocatalysis, Journal of Molecular Catalysis B: Enzymatic, vol.6, issue.3, pp.199-214, 1999.
DOI : 10.1016/S1381-1177(98)00123-4

W. Xu, J. H. Xu, J. Pan, Q. Gu, and X. Y. Wu, Enantioconvergent Hydrolysis of Styrene Epoxides by Newly Discovered Epoxide Hydrolases in Mung Bean, Organic Letters, vol.8, issue.8, pp.1737-1740, 2006.
DOI : 10.1021/ol060407u

S. S. Zinjarde and A. Pant, Emulsifier from a tropical marine yeast, Yarrowia lipolytica NCIM 3589, Journal of Basic Microbiology, vol.42, issue.1, pp.67-73, 2002.
DOI : 10.1002/1521-4028(200203)42:1<67::AID-JOBM67>3.0.CO;2-M

R. Altschul, S. F. Madden, T. L. Schaver, A. A. Zhang, J. Zhang et al., Gapped BLAST and PSI-BLAST: a new generation of protein database search programs, Nucleic Acids Research, vol.25, issue.17, pp.3389-3402, 1997.
DOI : 10.1093/nar/25.17.3389

G. Barth, J. Beckerich, A. Dominguez, S. Kerscher, D. Ogrydziak et al., Functional genetics of Yarrowia lipolytica Functional Genetics of industrial yeasts, pp.227-271, 2003.

G. Barth and C. Gaillardin, Yarrowia lipolytica, Nonconventional Yeasts in Biotechnology, pp.313-388, 1996.
DOI : 10.1007/978-3-642-38583-4

G. Barth and T. Scheuber, Cloning of the isocitrate lyase gene (ICL1) from Yarrowia lipolytica and characterization of the deduced protein, MGG Molecular & General Genetics, vol.241, issue.3-4, 1993.
DOI : 10.1007/BF00284696

J. B. Bassel and R. K. Mortimer, Genetic and biochemical studies of N-alkane non-ultilzing mutants of Saccharomycopsis lipolytica, Current Genetics, vol.38, issue.2, pp.77-88, 1982.
DOI : 10.1007/BF00365697

J. B. Bassel and R. K. Mortimer, Identification of mutations preventing n-hexadecane uptake among 26 n-alkane non-utilizing mutants of Yarrowia (Saccharomycopsis) lipolytica, Current Genetics, vol.1, issue.7, pp.579-586, 1985.
DOI : 10.1007/BF00381171

M. Bowker-kinley and K. M. Popov, Evidence that pyruvate dehydrogenase kinase belongs to the ATPase/kinase superfamily, Biochemical Journal, vol.344, issue.1, pp.47-53, 1999.
DOI : 10.1042/bj3440047

D. Hertogh, B. Hancy, F. Goveau, A. Baret, and P. V. , Emergence of Species-Specific Transporters During Evolution of the Hemiascomycete Phylum, Genetics, vol.172, issue.2, pp.771-781, 2006.
DOI : 10.1534/genetics.105.046813

M. Devic, S. Albert, M. Delseny, and T. Roscoe, EYcient PCR walking on plant genomic DNA, Plant Physiol. Biochem, vol.35, pp.331-339, 1997.

A. Dominguez, E. Ferminan, and C. Gaillardin, <i>Yarrowia lipolytica</i>: An Organism Amenable to Genetic Manipulation as a Model for Analyzing Dimorphism in Fungi, Contrib. Microbiol, vol.5, pp.151-172, 2000.
DOI : 10.1159/000060349

F. Thevenieau, ARTICLE IN PRESS Please cite this article in press as Characterization of Yarrowia lipolytica mutants aVected in hydrophobic substrate utilization, Fungal Genet. Biol, 2006.

P. Fickers, J. M. Nicaud, C. Gaillardin, J. Destain, and P. Thonart, Carbon and nitrogen sources modulate lipase production in the yeast Yarrowia lipolytica, Journal of Applied Microbiology, vol.167, issue.4, pp.742-749, 2004.
DOI : 10.1016/0006-3002(58)90097-0

S. Fukui and A. Tanaka, Metabolism of alkanes by yeasts, Adv. Biochem . Eng, vol.19, pp.217-237, 1981.
DOI : 10.1007/3-540-10464-X_19

C. O. Gill and C. Ratledge, Toxicity of n-Alkanes, n-Alk-1-enes, n-Alkan-1-ols and n-Alkyl-1-bromides towards Yeasts, Journal of General Microbiology, vol.72, issue.1, pp.165-172, 1972.
DOI : 10.1099/00221287-72-1-165

T. Iida, A. Ohta, and M. Takagi, Cloning and characterization of an nalkane-inducible cytochrome P450 gene essential for n-decane assimilation by Yarrowia lipolytica, pp.1387-1397, 1998.

A. P. Ilchenko, I. G. Morgunov, H. Honeck, S. Mauersberger, N. N. Vasylkova et al., PuriWcation and some properties of alcohol oxidase from the yeast Yarrowia lipolytica H222, Biokhimiya (Moscow ), vol.59, pp.1312-1319, 1994.

T. Juretzek, H. J. Wang, J. Nicaud, S. Mauersberger, and G. Barth, Comparison of promoters suitable for regulated overexpression of ??-galactosidase in the alkane-utilizing yeastYarrowia lipolytica, Biotechnology and Bioprocess Engineering, vol.25, issue.5, pp.320-326, 2000.
DOI : 10.1007/BF02942206

T. Kim, O. Young-sook, and S. Kim, The possible involvement of the cell surface in aliphatic hydrocarbon utilization by an oil degrading yeast Yarrowia lipolytica 180, J. Microbiol. Biotechnol, vol.10, pp.333-337, 2000.

M. Kujau, H. Weber, and G. Barth, Characterization of mutants of the yeast Yarrowia lipolytica defective in acetyl-coenzyme A synthetase, pp.193-203, 1992.

F. M. Lasorsa, P. Scarcia, R. Erdmann, F. Palmieri, H. Rottensteiner et al., The yeast peroxisomal adenine nucleotide transporter: characterization of two transport modes and involvement in ??pH formation across peroxisomal membranes, Biochemical Journal, vol.381, issue.3, pp.581-585, 2004.
DOI : 10.1042/BJ20040856

S. Mauersberger, Mutants of alkane oxidation in the yeasts Yarrowia lipolytica and Candida maltosa Alkane metabolism and oversynthesis of metabolites by microorganisms, Center for Biological Research USSR Academy of Sciences, pp.59-78, 1991.

S. Mauersberger, H. Drechsler, G. Oehme, and H. G. Müller, Substrate speciWcity and stereoselectivity of fatty alcohol oxidase from the yeast Candida maltosa, Appl. Microbiol. Biotechnol, vol.37, pp.66-73, 1992.

S. Mauersberger and J. M. Nicaud, Tagging genes by insertionnal mutagenesis in the yeast Yarrowia lipolytica Laboratory manual on non-conventional yeast in genetics, pp.343-356, 2003.

S. Mauersberger, M. Ohkuma, W. Schunck, and M. Takagi, Candida maltosa, Nonconventional Yeasts in Biotechnology, pp.411-580, 1996.
DOI : 10.1007/978-3-642-79856-6_12

S. Mauersberger, H. J. Wang, C. Gaillardin, G. Barth, and J. M. Nicaud, Insertional Mutagenesis in the n-Alkane-Assimilating Yeast Yarrowia lipolytica: Generation of Tagged Mutations in Genes Involved in Hydrophobic Substrate Utilization, Journal of Bacteriology, vol.183, issue.17, pp.5102-5109, 2001.
DOI : 10.1128/JB.183.17.5102-5109.2001

R. A. Monge, E. Roman, C. Nombela, and J. Pla, The MAP kinase signal transduction network in Candida albicans, Microbiology, vol.152, issue.4, pp.905-912, 2006.
DOI : 10.1099/mic.0.28616-0

T. Nazarko, M. Mala, J. Nicaud, and A. Sibirny, Mutants of the yeast Yarrowia lipolytica deWcient in the inactivation of peroxisomal enzymes, Biology Series, vol.35, pp.128-136, 2004.

T. Nazarko, M. Mala, and A. Sibirny, Development of the plate assay screening procedure for isolation of the mutants deficient in inactivation of peroxisomal enzymes in the yeast Yarrowia lipolytica, Biopolymers and Cell, vol.18, issue.2, pp.135-138, 2002.
DOI : 10.7124/bc.0005F5

W. M. Nuttley, A. M. Brade, C. Gaillardin, G. A. Eitzen, J. R. Glover et al., Rapid identiWcation and characterization of peroxisomal assembly mutants in Yarrowia lipolytica, pp.507-517, 1993.

M. Ohkuma, T. Zimmer, T. Iida, W. H. Schunck, A. Ohta et al., Isozyme Function of n-Alkane-inducible Cytochromes P450 in Candida maltosa Revealed by Sequential Gene Disruption, Journal of Biological Chemistry, vol.273, issue.7, pp.3948-3953, 1998.
DOI : 10.1074/jbc.273.7.3948

M. Osumi, F. Fukuzumi, N. Yamada, T. Nagatani, Y. Teranishi et al., Surface structure of some Candida yeast cells grown on n-alkanes, J. Ferment. Technol, vol.53, pp.244-248, 1975.

L. Palmieri, F. M. Lasorsa, D. Palma, A. Palmieri, F. Runswick et al., Identification of the yeast ACR1 gene product as a succinate-fumarate transporter essential for growth on ethanol or acetate, FEBS Letters, vol.6, issue.1, pp.114-118, 1997.
DOI : 10.1016/S0014-5793(97)01269-6

L. Palmieri, F. M. Lasorsa, A. Vozza, G. Agrimi, G. Fiermonte et al., Identification and functions of new transporters in yeast mitochondria, Biochimica et Biophysica Acta (BBA) - Bioenergetics, vol.1459, issue.2-3, pp.363-369, 2000.
DOI : 10.1016/S0005-2728(00)00173-0

L. Palmieri, H. Rottensteiner, W. Girzalsky, P. Scarcia, F. Palmieri et al., Identification and functional reconstitution of the yeast peroxisomal adenine nucleotide transporter, The EMBO Journal, vol.20, issue.18, pp.5049-5059, 2001.
DOI : 10.1093/emboj/20.18.5049

H. Rottensteiner, L. Palmieri, A. Hartig, B. Hamilton, H. Ruis et al., The peroxisomal transporter gene ANT1 is regulated by a deviant oleate response element (ORE): characterization of the signal for fatty acid induction, Biochemical Journal, vol.365, issue.1, pp.109-117, 2002.
DOI : 10.1042/bj20011495

J. Sikkema, J. A. De-bont, and B. Poolman, Mechanisms of membrane toxicity of hydrocarbons, Microbiol. Rev, vol.59, pp.201-222, 1995.

J. J. Smith and R. A. Rachubinski, A Role for the Peroxin Pex8p in Pex20p-dependent Thiolase Import into Peroxisomes of the Yeast Yarrowia lipolytica, Journal of Biological Chemistry, vol.276, issue.2, pp.1618-1625, 2001.
DOI : 10.1074/jbc.M005072200

F. Thevenieau, PRESS Please cite this article in press as Characterization of Yarrowia lipolytica mutants aVected in hydrophobic substrate utilization, Fungal Genetics and Biology Fungal Genet. Biol, 2006.

O. V. Stasyk, T. Y. Nazarko, O. G. Stasyk, O. S. Krasovska, D. Warnecke et al., Sterol glucosyltransferases have different functional roles inPichia pastoris and Yarrowia lipolytica, Cell Biology International, vol.27, issue.11, pp.947-952, 2003.
DOI : 10.1016/j.cellbi.2003.08.004

M. Takagi, T. Sumita, S. Yamagami, T. Iida, Y. Nagata et al., A genetic system for isolation of genes encoding regulators of cytochrome P450 gene expression for n-alkane assimilation, II Yarrowia lipolytica International Meeting, p.23, 1999.

T. Takewaka, T. Zimmer, A. Hirata, A. Ohta, and M. Takagi, Null Mutation in IRE1 Gene Inhibits Overproduction of Microsomal Cytochrome P450Alkl (CYP 52A3) and Proliferation of the Endoplasmic Reticulum in Saccharomyces cerevisiae, Journal of Biochemistry, vol.125, issue.3, pp.507-514, 1999.
DOI : 10.1093/oxfordjournals.jbchem.a022314

A. Tanaka and S. Fukui, Metabolism of n-alkanes The Yeast. Metabolism and Physiology of Yeasts, pp.261-287, 1989.

V. I. Titorenko, D. M. Ogrydziak, and R. A. Rachubinski, Four distinct secretory pathways serve protein secretion, cell surface growth, and peroxisome biogenesis in the yeast Yarrowia lipolytica., Molecular and Cellular Biology, vol.17, issue.9, pp.5210-5226, 1997.
DOI : 10.1128/MCB.17.9.5210

V. I. Titorenko and R. A. Rachubinski, Dynamics of peroxisome assembly and function, Trends in Cell Biology, vol.11, issue.1, pp.22-29, 2001.
DOI : 10.1016/S0962-8924(00)01865-1

C. W. Van-roermund, R. Drissen, . Van-den, M. Berg, L. Ijlst et al., Identification of a Peroxisomal ATP Carrier Required for Medium-Chain Fatty Acid ??-Oxidation and Normal Peroxisome Proliferation in Saccharomyces cerevisiae, Molecular and Cellular Biology, vol.21, issue.13, pp.4321-4329, 2001.
DOI : 10.1128/MCB.21.13.4321-4329.2001

S. Yamagami, T. Iida, Y. Nagata, A. Ohta, and M. Takagi, Isolation and Characterization of Acetoacetyl-CoA Thiolase Gene Essential for n-Decane Assimilation in Yeast Yarrowia lipolytica, Biochemical and Biophysical Research Communications, vol.282, issue.3, pp.832-838, 2001.
DOI : 10.1006/bbrc.2001.4653

T. Zimmer, T. Iida, W. H. Schunck, Y. Yoshida, A. Ohta et al., Relation Between Evolutionary Distance and Enzymatic Properties among the Members of the CYP52A Subfamily ofCandida maltosa, Biochemical and Biophysical Research Communications, vol.251, issue.1, pp.244-247, 1998.
DOI : 10.1006/bbrc.1998.9450