Multi-electrode system design and optimization for cardiac implants

Abstract : Cardiac implants like ICD are life saving devices for cardiac arrhythmias. In other conditions like heart failure, CRT implants are prescribed to restore the heart rhythm. Such treatment consists of the delivery of electrical stimuli to the cardiac tissue via electrodes in the stimulation lead. Conventionally the stimulation lead come either in unipolar or bipolar configuration which have been found to be sufficient for pacing the right atrium and right ventricle, studies have shown the benefits of a multi-electrode system for pacing left ventricle essential for cardiac resynchronization. This thesis discusses the design and optimization of a multi-electrode system capable of alleviating the limitations and constraints related to left ventricular stimulation. We first present implementation of such system that was taped out in 0.18 µm technology. The chip also features a specially designed communication protocol which enables low power operation and quick configuration. Thereafter we present the design and implementation of a default connection unit to ensure the compatibility of our multi-electrode lead with in the market. This unit was taped out in 0.18 µm technology. Finally we present a proof of concept study for the adaptation and integration of non-volatile memory technologies within the multi-electrode system. The employment of such technologies enhanced our multi-electrode system by eliminating the repetitive configuration of electrodes, thereby saving power and reducing latency. This also included smaller area and compatibility with any pacemaker in the market. Through simulations we proved the feasibility of these technologies for our implant applications.
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Islam Seoudi. Multi-electrode system design and optimization for cardiac implants. Other. Télécom ParisTech, 2012. English. ⟨NNT : 2012ENST0027⟩. ⟨tel-01081680⟩

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