Imagerie échographique ultrarapide du cœur et des artères chez l’homme : Vers l’imagerie ultrarapide 3D et l’imagerie du tenseur de rétrodiffusion ultrasonore

Abstract : In this thesis, we investigated various aspects of ultrafast ultrasound imaging of the cardiovascular system. First, we quantified the arterial stiffness with shear wave imaging and its dependence with stress, anisotropy and blood pressure. Thanks to experiments on an ex vivo horse artery and on in vivo rat arteries we measured the dependence with arterial pressure and arterial stiffness and were able to propose a method that quantifies non-invasively, the non-linear elastic parameter of arteries. In a second part, we have developed non-invasive ultrafast imaging of the human heart with coherent compounding of diverging waves. With this tool, we were able to visualize natural waves and to image shear waves in vivo in the human heart with increased sensitivity. In a third part, we have developed an original method to map the tissue microstructure that relies on the anisotropy of the spatial coherence of backscattered ultrasound from plane wave coherent compounding. With this method, we have successfully detected fiber directions ex vivo in anisotropic soft tissues such as the heart. Finally, we developed 3D ultrafast ultrasound imaging in real time, using a 2D matrix array probe with 1024 elements and a customized, programmable, 1024 channel ultrasound system. We successfully measured in 3D flow in vivo in the heart and the carotid artery, the propagation of pulse wave and shear wave in vivo and ex vivo respectively. The study of spatial coherence of backscattered field with the 2D matrix array enabled the mapping of the fibers in biological anisotropic soft tissues in entire 3D volumes.
Liste complète des métadonnées

Cited literature [166 references]  Display  Hide  Download

https://pastel.archives-ouvertes.fr/tel-01091484
Contributor : Clement Papadacci <>
Submitted on : Friday, December 5, 2014 - 2:54:17 PM
Last modification on : Thursday, April 4, 2019 - 1:31:56 AM
Document(s) archivé(s) le : Saturday, April 15, 2017 - 4:02:46 AM

Identifiers

  • HAL Id : tel-01091484, version 1

Citation

Clément Papadacci. Imagerie échographique ultrarapide du cœur et des artères chez l’homme : Vers l’imagerie ultrarapide 3D et l’imagerie du tenseur de rétrodiffusion ultrasonore. Physique Médicale [physics.med-ph]. Université Paris-Diderot Paris 7, 2014. Français. ⟨tel-01091484⟩

Share

Metrics

Record views

636

Files downloads

1292