Skip to Main content Skip to Navigation

MSPT : Motion Simulator for Proton Therapy

Abstract : In proton therapy, the delivery method named spot scanning, can provide a particularly efficient treatment in terms of tumor coverage and healthy tissues protection. The dosimetric benefits of proton therapy may be greatly degraded due to intra-fraction motions. Hence, the study of mitigation or adaptive methods is necessary. For this purpose, we developed an open-source 4D dose computation and evaluation software, MSPT (Motion Simulator for Proton Therapy), for the spot-scanning delivery technique. It aims at highlighting the impact of intra-fraction motions during a treatment delivery by computing the dose distribution in the moving patient. In addition, the use of MSPT allowed us to develop and propose a new motion mitigation strategy based on the adjustment of the beam's weight when the proton beam is scanning across the tumor. In photon therapy, a main concern for deliveries using a multileaf collimator (MLC) relies on finding a series of MLC configurations to deliver properly the treatment. The efficiency of such series is measured by the total beam-on time and the total setup time. In our work, we study the minimization of these efficiency criteria from an algorithmic point of view, for new variants of MLCs: the rotating MLC and the dual-layer MLC. In addition, we propose an approximation algorithm to find a series of configurations that minimizes the total beam-on time for the rotating MLC
Document type :
Complete list of metadata

Cited literature [89 references]  Display  Hide  Download
Contributor : ABES STAR :  Contact
Submitted on : Friday, March 6, 2015 - 10:24:49 PM
Last modification on : Saturday, January 15, 2022 - 3:58:13 AM
Long-term archiving on: : Sunday, June 7, 2015 - 6:20:34 PM


Version validated by the jury (STAR)


  • HAL Id : tel-01126872, version 1


Paul Morel. MSPT : Motion Simulator for Proton Therapy. Autre [cs.OH]. Université Paris-Est, 2014. Français. ⟨NNT : 2014PEST1094⟩. ⟨tel-01126872⟩



Record views


Files downloads