Skip to Main content Skip to Navigation

Les aérogels de pectine : matériaux avancés pour l'isolation thermique et la libération de médicaments

Abstract : Aerogels are ultra-light, highly porous and nano-structured materials with high specific surface area. Bio-aerogels are a new generation of aerogels that are fully biomass-based, which opens up a lot of potentials in biomass valorization and life science applications. In this work pectin was used to produce bio- aerogels. Two main objectives were achieved : • The first was to understand and correlate the characteristics of pectin and the preparation conditions with the internal structure of aerogel and its physico-chemical properties. • The second was to evaluate and develop pectin aerogels as advanced bio-materials for the two different applications : thermal insulation and drug delivery. Various mechanisms of network formation, gelation and non-solvent induced phase separation, were demonstrated to play a very important role in aerogel morphology and properties. Thermal conductivity of pectin aerogels was very low, around 0.015 - 0.020 W/(m.K), and showing U-shape dependence on density. When used as drug delivery matrices, the kinetics of drug release was correlated with pectin aerogels’ structure and density. Composite cellulose-pectin and silica-pectin aerogels were synthesized and also used as drug carriers; a prolonged release was recorded. A high potential of pectin aerogels to be used as versatile bio-materials with advanced tunable functionalities was demonstrated.
Document type :
Complete list of metadata

Cited literature [286 references]  Display  Hide  Download
Contributor : ABES STAR :  Contact
Submitted on : Thursday, December 19, 2019 - 6:41:05 PM
Last modification on : Friday, April 29, 2022 - 9:34:00 AM
Long-term archiving on: : Friday, March 20, 2020 - 9:48:02 PM


Version validated by the jury (STAR)


  • HAL Id : tel-02420381, version 1


Sophie Groult. Les aérogels de pectine : matériaux avancés pour l'isolation thermique et la libération de médicaments. Matériaux. Université Paris sciences et lettres, 2019. Français. ⟨NNT : 2019PSLEM016⟩. ⟨tel-02420381⟩



Record views


Files downloads