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Développement d’un outil EHD microfluidique pour la mesure de propriétés physico-chimiques

Abstract : High- throughput experimentation (HTE) represents a growing demand in the field of research. Microfluidics, and in particular digital microfluidics, have been cited as a promising method in this field for several years now. Indeed, it allows the use of small volumes but especially the possibility ton consider each droplet as an independent microreactor. The analysis of the content of the droplet is often performed on its optical properties. We want to open this analysis to other properties, especially physicochemical properties, such as viscosity. The objective of this work is the development of a chip for the high-throughput measurement of viscosity in digital microfluidics. To achieve this goal, we have chosen to study the phenomenon of deformation and relaxation of a droplet at the exit of a microfluidic constriction. In the case of Newtonian fluids, we have established a correlation linking the maximum deformation of the droplet to the different numbers governing the phenomenon and in particular the viscosity. We have also shown that the correlation found is valid when complex fluids are in presence such as fluids containing surfactants or non-Newtonian polymers. The integration of a mixer to the microfluidic chip allows to make a first step towards high-throughput experimentation because our chip thus makes it possible to obtain quickly a measurement of viscosity on samples of different compositions applicable to complex fluids.
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Submitted on : Thursday, March 19, 2020 - 2:25:10 PM
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  • HAL Id : tel-02512195, version 1


Estelle Andre. Développement d’un outil EHD microfluidique pour la mesure de propriétés physico-chimiques. Chimie-Physique [physics.chem-ph]. Université Paris sciences et lettres, 2018. Français. ⟨NNT : 2018PSLET029⟩. ⟨tel-02512195⟩



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