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,
, Initialement développées en astronomie, des méthodes d'optique adaptative ont été transposées en microscopie afin de compenser les effets dues aux aberrations. Celles-ci reposent principalement sur la mesure du front d'onde et sur la correction en boucle fermée des aberrations à l'aide de dispositifs de contrôle du front d'onde. Ces méthodes sont toutefois limitées par les cadences de mesure et de correction, Les techniques de microscopie interférométrique présentent une sensibilité aux aberrations qui limite leurs pouvoirs de résolution et de pénétration dans les tissus biologiques
, matricielle innovante reposant sur l'étude d'un nouvel opérateur, la matrice distorsion, permettant de quantifier localement les paramètres liés aux aberrations et à la diffusion, et de corriger les aberrations sur l'ensemble du champs de vision même en présence de plusieurs aires d'isoplanétisme. En parallèle, nous présentons un formalisme mathématique permettant d'expliquer la manifestation des aberrations en OCT plein champ et étendons le champ d'application de la méthode matricielle à de vastes champs de vision au moyen d'un dispositif expérimental de mesure de la matrice de réflexion
,
Most of them rely on the measurement of the wave front and on a close-loop correction of the aberrations using wave-front control devices. These methods are nevertheless limited by the rates of measurement and correction and can only compensate for low-order aberrations. The purpose of this thesis is to present an innovative matrix approach relying on the analysis of a new operator, the distorsion matrix, allowing to locally quantify the scattering and aberration parameters, and to compensate for the aberrations over the whole field of view for different isolanatic areas. Besides, we introduce a mathematical formalism in order to describe the effects of aberrations in full-field OCT and we extend the scope of the matrix approach to very large fields of view thanks to an experimental setup of reflection matrix measurement inspired by this technique of imaging ,