M. H. El-salam and S. El-shibiny, Bioactive Peptides of Buffalo, Camel, Goat, Sheep, Mare, and Yak Milks and Milk Products, Food Reviews International, vol.29, issue.1, pp.1-23, 2012.

K. Erdmann, B. W. Cheung, and H. Schröder, The possible roles of food-derived bioactive peptides in reducing the risk of cardiovascular disease, The Journal of Nutritional Biochemistry, vol.19, issue.10, pp.643-654, 2008.

F. J. Espejo-carpio, C. De-gobba, A. Guadix, E. M. Guadix, and J. Otte, Angiotensin I-converting enzyme inhibitory activity of enzymatic hydrolysates of goat milk protein fractions, International Dairy Journal, vol.32, issue.2, pp.175-183, 2013.

T. Faye, A. Tamburello, G. E. Vegarud, and S. Skeie, Survival of lactic acid bacteria from fermented milks in an in vitro digestion model exploiting sequential incubation in human astric and duodenum juice, Journal of dairy science, vol.95, pp.558-566, 2012.

G. Gardiner, R. P. Ross, J. K. Collins, G. Fitzgerald, and C. Stanton, Development of a Probiotic Cheddar Cheese Containing Human-Derived Lactobacillus paracasei Strains, Applied and Enviromental Microbiology, vol.64, issue.6, pp.2192-2199, 1998.

J. J. Godon, E. Zumstein, P. Dabert, F. Habouzit, and R. Moletta, Molecular microbial diversity of an anaerobic digestor as determined by small-subunit rDNA sequence analysis, Applied and Environmental Microbiology, vol.63, issue.7, pp.2802-2813, 1997.
URL : https://hal.archives-ouvertes.fr/hal-02686242

J. Á. Gómez-ruiz, I. López-expósito, A. Pihlanto, M. Ramos, and I. Recio, , 2008.

, Antioxidant activity of ovine casein hydrolysates: identification of active peptides by HPLC-MS/MS, European Food Research and Technology, vol.227, issue.4, pp.1061-1067

A. F. González-córdova, C. Yescas, A. M. Ortiz-estrada, M. A. De-la-rosa-alcaraz, A. Hernández-mendoza et al., Invited review: Artisanal Mexican cheeses, Journal of dairy science, vol.99, pp.1-13, 2016.

D. Gonzalez-de-llano, M. C. Polo, and M. Ramos, Study of Proteolysis in Liquid Chromatography Artisanal Cheeses: High Performance of Peptides, Journal of dairy science, vol.78, pp.1018-1024, 1995.

J. A. Guerra-martínez, J. G. Montejano, and S. T. Martín-del-campo, Evaluation of proteolytic and physicochemical changes during storage of fresh Panela cheese from, 2012.

. Queretaro, Mexico and its impact in texture, CyTA -Journal of Food, vol.10, issue.4, pp.296-305

P. L. Mcsweeney and P. F. Fox, Chemical methods for the characterization of proteolysis in cheese during ripening, Lait, vol.77, pp.41-76, 1997.
URL : https://hal.archives-ouvertes.fr/hal-00929515

P. L. Mcsweeney, P. F. Fox, J. A. Lucey, K. N. Jordan, and T. M. Cogan, Contribution of the Indigenous Microflora to the Maturation of Cheddar Cheese, International Dairy Journal, vol.3, issue.93, pp.90104-90112, 1993.

S. M. Meira, D. J. Daroit, V. E. Helfer, A. P. Corrêa, J. Segalin et al., Bioactive peptides in water-soluble extracts of ovine cheeses from Southern Brazil and Uruguay, Food Research International, vol.48, issue.1, pp.322-329, 2012.

H. Meisel, Multifunctional peptides encrypted in milk proteins, BioFactors, vol.21, pp.55-61, 2004.

C. Monnet, S. Landaud, P. Bonnarme, and D. Swennen, Growth and adaptation of microorganisms on the cheese surface, FEMS Microbiology Letters, vol.263, issue.1, pp.1-9, 2014.
URL : https://hal.archives-ouvertes.fr/hal-01535275

J. Mounier, M. C. Rea, P. M. O´connor, G. F. Fitzgerald, and T. M. Cogan, Isolated from Surface-Ripened Cheese, Characteristics of Brevibacterium, Corynebacterium, Microbacterium, and Staphylococcus spp, vol.73, pp.7723-7739, 2007.
URL : https://hal.archives-ouvertes.fr/hal-00557184

L. Ong, A. Henriksson, N. Shah, and P. , Angiotensin converting enzyme-inhibitory activity in Cheddar cheeses made with the addition of probiotic Lactobacillus casei sp, 2007.
URL : https://hal.archives-ouvertes.fr/hal-00895638

, Lait, vol.87, pp.149-165

L. A. Panizzolo, A. C. Arujo, L. V. Taroco, A. Rodriguez, and G. Schopf, Evolución de la proteólisis durante la maduración de quesos Danbo elaborados con distintos cultivos iniciadores, REVISTA DEL LABORATORIO TECNOLÓGICO DEL References, 2011.

N. Adouard, L. Magne, T. Cattenoz, H. Guillemin, B. Foligné et al., Survival of cheese-ripening microorganisms in a dynamic simulator of the gastrointestinal tract. Food Microbiology, 53 part A, 30-40, 2016.
URL : https://hal.archives-ouvertes.fr/hal-02638625

V. S. Bezerra, J. F. Campos, R. A. Da-silva, T. S. Porto, J. S. De-lima-filho et al., Biotechnological richness of the northeastern semi-arid region: antioxidant activity of casein hydrolysates from Moxotó goat milk (Capra hircus Linnaeus, 1758) obtained by papain action, Food Science and Technology, vol.33, issue.3, pp.513-520, 2013.

C. De-simone, G. Picariello, G. Mamone, P. Stiuso, A. Dicitore et al., , 2009.

, Characterisation and cytomodulatory properties of peptides from Mozzarella di Bufala Campana cheese whey, Journal of Peptide Science, vol.15, pp.251-258

A. Gupta, B. Mann, R. Kumar, and R. B. Sangwan, Antioxidant activity of Cheddar cheeses at different stages of ripening, International Journal of Dairy Technology, vol.62, issue.3, 2009.

C. Lay, M. Sutren, P. Lepercq, C. Juste, L. Rigottier-gois et al.,

C. Andrieux, Influence of Camembert consumption on the composition and metabolism of intestinal microbiota: a study in human microbiota-associated rats, British Journal of Nutrition, vol.92, pp.429-438, 2004.
URL : https://hal.archives-ouvertes.fr/hal-02682853

I. Sumeri, S. Adamberg, R. Uusna, I. Sarand, and T. Paalme, Survival of cheese bacteria in a gastrointestinal tract simulator, International Dairy Journal, vol.25, pp.36-41, 2012.

, Cheese. Food Science and Biotechnology, vol.20, issue.4, pp.997-1003

I. Franco, B. Prieto, R. Urdiales, J. M. Fresno, and J. Carballo, Study of the biochemical changes during ripening of Ahumado de Áliva cheese: a Spanish traditional variety, Food Chemistry, vol.74, pp.463-469, 2001.

M. Gobbetti, Extra-hard varieties. Cheese: Chemistry, Physics and Microbiology, vol.2, pp.51-70, 2004.

M. Gobbetti, L. Stepaniak, M. De-angelis, A. Corsetti, and R. Di-cagno, Latent bioactive peptides in milk proteins: proteolytic activation and significance in dairy processing, Critical Reviews in Food Science and Nutrition, vol.42, issue.3, pp.223-239, 2002.

D. Gonzalez-de-llano, M. C. Polo, and M. Ramos, Study of Proteolysis in Liquid Chromatography Artisanal Cheeses: High Performance of Peptides, Journal of dairy science, vol.78, pp.1018-1024, 1995.

J. A. Guerra-martínez, J. G. Montejano, and S. T. Martín-del-campo, Evaluation of proteolytic and physicochemical changes during storage of fresh Panela cheese from, 2012.

. Queretaro, Mexico and its impact in texture, CyTA -Journal of Food, vol.10, issue.4, pp.296-305

A. Gupta, B. Mann, R. Kumar, and R. B. Sangwan, Antioxidant activity of Cheddar cheeses at different stages of ripening, International Journal of Dairy Technology, vol.62, issue.3, 2009.

A. Gupta, B. Mann, R. Kumar, and R. B. Sangwan, ACE-Inhibitory Activity of Cheddar Cheeses Made with Adjunct Cultures at Different Stages of Ripening, Advances in Dairy Research, issue.1, p.1, 2013.

A. A. Hayaloglu, B. H. Ozer, and P. F. Fox, Cheeses of Turkey: 2. Varieties ripened under brine, Dairy Science and Technology, vol.88, pp.225-244, 2008.
URL : https://hal.archives-ouvertes.fr/hal-00895677

C. Hernández-morales, A. Hernández-montes, E. Aguirre-mandujano, and A. Villegas, Physicochemical, microbiological, textural and sensory characterisation of Mexican Añejo cheese, .x cultivos iniciadores, vol.63, pp.24-27, 2010.

M. Pavia, A. J. Trujillo, B. Guamis, and V. Ferragut, Ripening control of salt-reduced Manchego-type cheeseobtained by brine vacuum-mpregnation, Food Chemistry, vol.70, pp.155-162, 2000.

A. Perna, I. Intaglietta, A. Simonetti, and E. Gambacorta, Short communication: Effect of genetic type on antioxidant activity of Caciocavallo cheese during ripening, Journal of dairy science, vol.98, pp.3690-3694, 2015.

A. Pihlanto, Antioxidative peptides derived from milk proteins, International Dairy Journal, vol.16, issue.11, pp.1306-1314, 2006.

T. Poméon, El queso Cotija, México. Un producto con marca colectiva queso "Cotija Región de origen, 2007.

S. R. Pritchard, M. Phillips, and K. Kailasapathy, Identification of bioactive peptides in commercial Cheddar cheese, Food Research International, vol.43, pp.1545-1548, 2010.

P. Ruas-madiedo, J. C. Bada-gancedo, T. Delgado, M. Gueimonde, and C. G. De-los-reyes-gavilán, Proteolysis in rennet-coagulated Spanish hard cheeses made from milk preserved by refrigeration and addition of carbon dioxide, Journal of Dairy Research, vol.79, pp.115-122, 2003.

E. Ryhänen, A. Pihlanto-leppälä, and E. Pahkala, A new type of ripened, low-fat cheese with bioactive properties, International Dairy Journal, vol.11, pp.441-447, 2001.

V. Vermeirssen, J. Van-camp, and W. Verstraete, Bioavailability of angiotensin I converting enzyme inhibitory peptides, British Journal of Nutrition, vol.92, pp.357-366, 2004.

A. M. Vivar-quintana, M. A. Blanco-lópez, I. Revilla, I. González-martín, J. M. Hernández-hierro et al., Seasonal Evolution of Hydrophilic and Hydrophobic Peptide Contents in Cheeses Made from Ewe's Goat's or Cow's Milk, Czech Journal of Food Science, vol.27, pp.5106-5108, 2009.

W. Wang, N. Wang, Y. Zhang, Z. Cai, Q. Chen et al., A Convenient RP-HPLC Method for Assay Bioactivities of Angiotensin I-Converting Enzyme Inhibitory Peptides, ISRN Biotechnology, 2013.

P. F. Fox and P. L. Mcsweeney, Proteolysis in cheese during ripening, Food Reviews International, vol.12, issue.4, pp.457-509, 1996.
URL : https://hal.archives-ouvertes.fr/hal-00929515

D. Gonzalez-de-llano, M. C. Polo, and M. Ramos, Study of Proteolysis in Liquid Chromatography Artisanal Cheeses: High Performance of Peptides, Journal of dairy science, vol.78, pp.1018-1024, 1995.

J. A. Guerra-martínez, J. G. Montejano, and S. T. Martín-del-campo, Evaluation of proteolytic and physicochemical changes during storage of fresh Panela cheese from, 2012.

. Queretaro, Mexico and its impact in texture, CyTA -Journal of Food, vol.10, issue.4, pp.296-305

A. Gupta, B. Mann, R. Kumar, and R. B. Sangwan, Antioxidant activity of Cheddar cheeses at different stages of ripening, International Journal of Dairy Technology, vol.62, issue.3, 2009.

A. Gupta, B. Mann, R. Kumar, and R. B. Sangwan, ACE-Inhibitory Activity of Cheddar Cheeses Made with Adjunct Cultures at Different Stages of Ripening, Advances in Dairy Research, issue.1, p.1, 2013.

B. Hajirostamloo, Bioactive component in milk and dairy product, World Acad Sci Eng Technol, vol.72, pp.162-166, 2010.

A. A. Hayaloglu and E. Y. Brechany, Influence of milk pasteurization and scalding temperature on the volatile compounds of Malatya, a farmhouse Halloumi-type cheese, Lait, vol.87, pp.39-57, 2007.
URL : https://hal.archives-ouvertes.fr/hal-00895632

B. Hernández-ledesma, L. Amigo, M. Ramos, and I. Recio, Angiotensin Converting Enzyme Inhibitory Activity in Commercial Fermented Products. Formation of Peptides under Simulated Gastrointestinal Digestion, Journal of Agricultural and Food Chemistry, vol.52, issue.6, pp.1504-1510, 2004.

B. Hernández-ledesma, M. Del-mar-contreras, and I. Recio, Antihypertensive peptides: Production, bioavailability and incorporation into foods, Advances in Colloid and Interface Science, vol.165, issue.1, pp.23-35, 2011.

L. Hernández-galán, A. Cardador-martínez, D. Picque, H. E. Spinnler, . López-del-castillo et al., Angiotensin converting enzyme inhibitors and antioxidant peptides release during ripening of Mexican Cotija hard cheese, Journal of Food Research, vol.5, issue.3, 2016.

P. Jäkälä and H. Vapaatalo, Antihypertensive Peptides from Milk Proteins, Pharmaceuticals, vol.3, issue.1, pp.251-272, 2010.

H. A. K?rmac?, A. A. Hayaloglu, H. B. Özer, A. F. Atasoy, and H. Türkoglud, Evolution of proteolysis in Urfa cheese made from ewe's milkby wild type starter culture systems, Small Ruminant Research, vol.119, pp.120-129, 2014.

D. D. Kitts and K. Weiler, Bioactive proteins and peptides from food sources. Applications of bioprocesses used in isolation and recovery, Current Pharmaceutical Design, vol.9, issue.16, pp.1309-1323, 2003.

H. Korhonen and A. Pihlanto, Food-derived Bioactive Peptides -Opportunities for Designing Future Foods, Current Pharmaceutical Design, vol.9, pp.1297-1308, 2003.

H. Korhonen and A. Pihlanto, Bioactive peptides: Production and functionality, International Dairy Journal, vol.16, pp.945-960, 2006.

C. Lacroix, P. Verret, and P. Paquin, Regional and Seasonal Variations of Nitrogen Fractions in Commingled Milk, International Dairy Journal, vol.6, pp.947-961, 1996.

H. Meisel, Multifunctional peptides encrypted in milk proteins, BioFactors, vol.21, pp.55-61, 2004.

M. M. Mullally, R. Mehra, and R. J. Fitzgerald, Thermal effects onthe conformation and susceptibility of beta-lactoglobulin to hydrolysis by gastric and pancreatic endoproteinases, Irish Journal of Agricultural and Food Research, vol.37, issue.1, pp.51-60, 1998.

K. F. Ng-kwai-hang, J. F. Hayes, J. E. Moxley, and H. G. Monardes, Variability of Test-Day Milk Production and Composition and Relation of Somatic Cell Counts with Yield and Compositional Changes of Bovine Milk, Journal of dairy science, vol.67, pp.361-366, 1984.

V. Olvera-garcía, A. Cardador-martínez, and S. T. Campo, Effect of Thermal Process and Filtration on the Antioxidant Activity and Physicochemical Parameters of Agave atrovirens Extracts, Journal of Food Research, vol.4, pp.155-167, 2015.

, Lait, vol.87, pp.149-165

M. Paul and D. L. Van-hekken, Assessing antihypertensive activity in native and model Queso Fresco cheeses, Journal of dairy science, vol.94, pp.2280-2284, 2011.

A. Pihlanto, Antioxidative peptides derived from milk proteins, International Dairy Journal, vol.16, issue.11, pp.1306-1314, 2006.

S. R. Pritchard, M. Phillips, and K. Kailasapathy, Identification of bioactive peptides in commercial Cheddar cheese, Food Research International, vol.43, pp.1545-1548, 2010.

L. Rinaldi, L. Rioux, M. Britten, and S. L. Turgeon, In vitro bioaccessibility of peptides and amino acids from yogurt made with starch, pectin, or ?-glucan, International Dairy Journal, pp.1-7, 2014.

D. Sánchez-macías, A. Morales-delanuez, I. Moreno-indias, L. E. Hernández-castellano, V. Mendoza-grimón et al., Lipolysis and proteolysis profiles of fresh artisanal goat cheese made with raw milk with 3 different fat contents, Journal of dairy science, vol.94, pp.5786-5793, 2011.

W. Scholz, Elaboración de quesos de oveja y de cabra, p.145, 1997.

S. Silva, A. Pihlanto, and F. Malcata, Bioactive Peptides in Ovine and Caprine Cheeselike Systems Prepared with Proteases from< i> Cynara cardunculus</i>, Journal of dairy science, vol.89, issue.9, pp.3336-3344, 2006.

J. Theolier, R. Hammami, I. Fliss, and J. Jean, Antibacterial and antifungal activity of water-soluble extracts from Mozzarella, Gouda, wiss, and Cheddar commercial cheeses produced in Canada, Dairy Science and Technology, vol.94, pp.427-438, 2014.

, Article: Effect of dairy matrices on the survival of Streptococcus thermophilus, References

N. Adouard, B. Foligné, J. Dewulf, M. Bouix, D. Picque et al., In vitro characterization of the digestive stress response and immunomodulatory properties of microorganisms isolated from smear-ripened cheese, International Journal of Food MIcrobiology, vol.197, pp.98-107, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01535293

M. M. Al-dabbas, K. Al-ismail, and B. M. Abdullah, Effect of Chemical Composition on the Buffering Capacity of Selected Dairy Products, Jordan Journal of Agricultural Sciences, vol.7, pp.690-700, 2011.

F. Barbé, S. Le-feunteun, D. Rémond, O. Ménard, J. Jardin et al.,

D. Dupont, , 2014.

, Tracking the in vivo release of bioactive peptides in the gut during digestion: Mass spectrometry peptidomic characterization of effluents collected in the gut of dairy matrix fed mini-pigs, Food Research International, vol.63, pp.147-156

M. Begley, C. G. Gahan, and C. Hill, The interaction between bacteria and bile, FEMS Microbiology Reviews, vol.29, pp.625-651, 2005.

E. Bobko, M. Tyras, and W. Jachymek, Reprint of ''New complete structure of Hafnia alvei clinical isolate strain PCM 2670 semi-rough lipopolysaccharide, Carbohydrate Research, vol.378, pp.71-78, 2013.

B. Bogovic-matijasic, T. Obermajer, L. Lipoglavsek, T. Sernel, I. Locatelli et al.,

R. Rogelj, Effects of synbiotic fermented milk containing Lactobacillus acidophilus La-5 and Bifidobacterium animalis ssp. lactis BB-12 on the fecal microbiota of adults with irritable bowel syndrome: A randomized double-blind, placebo-controlled trial, Journal of dairy science, vol.99, pp.1-14, 2015.

N. A. Bokulich, S. Subramanian, J. J. Faith, D. Gevers, J. I. Gordon et al., Quality-filtering vastly improves diversity estimates from Illumina amplicon sequencing, Nature methods, vol.10, issue.1, pp.57-59, 2013.

C. Bourlieu, O. Ménard, A. De-la-chevasnerie, L. Sams, F. Rousseau et al., , p.184

D. Dupont, The structure of infant formulas impacts their lipolysis, proteolysis and disintegration during in vitro gastric digestion, Food Chemistry, vol.182, pp.224-235, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01209795

J. Calbet and D. Maclean, Role of caloric content on gastric emptying in humans, The Journal of physiology, vol.498, p.553, 1997.

J. G. Caporaso, J. Kuczynski, J. Stombaugh, K. Bittinger, F. D. Bushman et al.,

J. I. Gordon, QIIME allows analysis of high-throughput community sequencing data, Nature methods, vol.7, issue.5, pp.335-336, 2010.

P. L. Conway, S. L. Gorbach, and B. R. Goldin, Survival of Lactic Acid Bacteria in the Human Stomach and Adhesion to Intestinal Cells, Journal of dairy science, vol.70, issue.1, pp.1-12, 1987.

W. P. Charteris, P. M. Kelly, L. Morelli, and J. K. Collins, Development and application of an in vitro methodology to determine the transit tolerance of potentially probiotic Lactobacillus and Bifidobacterium species in the upper human gastrointestinal tract, Journal of Applied Microbiology, vol.84, pp.759-768, 1998.

L. A. David, C. F. Maurice, R. N. Carmody, D. B. Gootenberg, J. E. Button et al.,

M. A. Fischbach, Diet rapidly and reproducibly alters the human gut microbiome, Nature, issue.7484, pp.559-563, 2014.

R. Del-campo, D. Bravo, R. Cantón, P. Ruiz-garbajosa, R. García-albiach et al., Scarce Evidence of Yogurt Lactic Acid Bacteria in Human Feces after Daily Yogurt Consumption by Healthy Volunteers, Applied and Enviromental Microbiology, vol.71, issue.1, pp.547-549, 2005.

E. J. Depeters, J. B. German, S. J. Taylor, S. T. Essex, and H. Perez-monti, Fatty Acid and Triglyceride Composition of Milk Fat from Lactating Holstein Cows in Response to Supplemental Canola Oil, Journal of dairy science, vol.84, issue.4, pp.929-936, 2001.

H. Devle, C. F. Naess-andresen, E. Rukke, G. E. Vegarud, D. Ekeberg et al., Rheological characterization of milk during digestion with human gastric and duodenal enzymes, Annual Transactions of the Nordic Rheology Society, p.20, 2012.

H. Devle, E. K. Ulleberg, C. F. Naess-andresen, E. Rukke, G. Vegarud et al., Reciprocal interacting effects of proteins and lipids during ex vivo digestion of 185 bovine milk, International Dairy Journal, vol.36, issue.1, pp.6-13, 2014.

A. P. Do-espirito-santo, P. Perego, A. Converti, and M. N. Oliveira, Influence of food matrices on probiotic viability -A review focusing on the fruity bases, Trends in Food Science and Technology, vol.22, pp.377-385, 2011.

R. C. Edgar, Search and clustering orders of magnitude faster than BLAST, 2010.

, Bioinformatics, vol.26, issue.19, pp.2460-2461

M. Elli, M. L. Callegari, S. Ferrari, E. Bessi, D. Cattivelli et al.,

J. Antoine, Survival of Yogurt Bacteria in the, Human Gut. Applied and Enviromental Microbiology, vol.72, issue.7, pp.5113-5117, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00294424

O. Firmesse, E. Alvaro, A. Mogenet, J. Bresson, R. Lemee et al., Fate and effects of Camembert cheese micro-organisms in the human colonic microbiota of healthy volunteers after regular Camembert consumption, International Journal of Food MIcrobiology, vol.125, pp.176-181, 2008.

J. García-hernández, Y. Moreno, C. Chuan, and M. Hernández, In Vivo Study of the Survival of Lactobacillus delbruecki subsp. bulgaricus CECT 4005T and Streptococcus thermophilus CECT 801 by DVC-FISH after Consumption of Fermented Milk, Journal of Food Science, vol.77, issue.10, pp.593-597, 2012.

H. Guillemin, B. Perret, D. Picque, O. Menard, and T. Cattenoz, Logiciel StoRMstomach and duodenum regulation and monitoring, 2010.

T. P. Guinee and D. J. O´callaghan, The formation of Cheese Curd, 2010.

N. Halgasova, G. Bukovska, J. Ugorcakova, J. Timko, and J. Kormanec, The Brevibacterium £avum sigma factor SigB has a role in the environmental stress response, FEMS Microbiology Letters, vol.216, pp.77-84, 2002.

J. A. Hannon, C. Lopez, M. N. Madec, and S. Lortal, Altering Renneting pH Changes Microstructure, Cell Distribution, and Lysis of Lactococcus lactis AM2 in Cheese Made from Ultrafiltered Milk, Journal of dairy science, vol.89, issue.3, pp.812-823, 2006.
URL : https://hal.archives-ouvertes.fr/hal-01453967

R. A. Inglingstad, T. G. Devold, E. K. Eriksen, H. Holm, M. Jacobsen et al.,

G. E. Vegarud, Comparison of the digestion of caseins and whey proteins in equine, bovine, caprine and human milks by human gastrointestinal enzymes, Dairy Sci. Technol, vol.90, issue.5, pp.549-563, 2010.
URL : https://hal.archives-ouvertes.fr/hal-00895747

F. Irlinger, . Ah-yuen-in, S. Yung, A. Sarthou, C. Delbès-paus et al.,

S. Helinck, Ecological and aromatic impact of two Gram-negative bacteria (Psychrobacter celer and Hafnia alvei) inoculated as part of the whole microbial community of an experimental smear soft cheese, International Journal of Food MIcrobiology, vol.153, pp.332-338, 2012.
URL : https://hal.archives-ouvertes.fr/hal-01001503

J. M. Janda and S. L. Abbott, The Genus Hafnia: from Soup to Nuts, Clinical Microbiology Reviews, vol.19, issue.1, pp.12-18, 2006.

T. Janhoj and K. B. Qvist, The formation of Cheese Curd, Techology of Cheesemaking, pp.130-156, 2010.

M. Johnson and B. A. Law, The Origins, Development and Basic Operations of Cheesemaking Technology, Technology of CheesemakingSociety of Dairy Technology book series, vol.1, pp.68-96, 2010.

F. Kong and R. P. Singh, Disintegration of Solid Foods in Human Stomach, Journal of Food Science, vol.73, issue.5, 2008.

C. Lay, M. Sutren, P. Lepercq, C. Juste, L. Rigottier-gois et al.,

A. Lazuka, L. Auer, S. Bozonnet, D. P. Morgavi, M. O'donohue et al., Efficient anaerobic transformation of raw wheat straw by a robust cow rumenderived microbial consortium, Bioresource Technology, vol.196, pp.241-249, 2015.
URL : https://hal.archives-ouvertes.fr/hal-01269314

J. Lucey, B. Hauth, C. Gorry, and P. Fox, The acid-base buffering properties of milk, Milchwissenschaft, vol.48, issue.5, pp.268-272, 1993.

Q. Lüthi-peng and Z. Puhan, Determination of protein and casein in milk by fourth derivative UV spectrophotometry, Analytica Chimica Acta, vol.393, issue.1-3, pp.227-234, 1999.

T. Mago? and S. L. Salzberg, FLASH: fast length adjustment of short reads to improve genome assemblies, Bioinformatics, vol.27, issue.21, pp.2957-2963, 2011.

P. Marteau, M. Minekus, R. Havenaar, . Huis-in´t, and J. H. Veld, Survival of Lactic Acid Bacteria in a Dynamic Model of the Stomach and Small Intestine: Validation and the Effects of Bile, Journal of dairy science, vol.80, issue.97, pp.76027-76029, 1997.

D. D. Mater, L. Bretigny, O. Firmesse, M. Flores, A. Mogenet et al., Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus survive gastrointestinal transit of healthy volunteers consuming yogurt, FEMS Microbiology Letters, vol.250, pp.185-187, 2005.
URL : https://hal.archives-ouvertes.fr/hal-02683460

M. E. Mcbee and D. B. Schauer, The Genus Hafnia, Proteobacteria: Gamma Subclass, vol.6, pp.215-218, 2006.

D. Mcdonald, M. N. Price, J. Goodrich, E. P. Nawrocki, T. Z. Desantis et al.,

P. Hugenholtz, An improved Greengenes taxonomy with explicit ranks for ecological and evolutionary analyses of bacteria and archaea, Food Chemistry, vol.6, issue.3, pp.1039-1045, 2012.

J. Mounier, M. C. Rea, P. M. O´connor, G. F. Fitzgerald, and T. M. Cogan, Characteristics of Brevibacterium, Corynebacterium, Microbacterium, and Staphylococcus spp, Applied and Enviromental Microbiology, vol.73, issue.23, pp.7723-7739, 2007.
URL : https://hal.archives-ouvertes.fr/hal-00557184

P. W. Parodi, Positional distribution of fatty acids in triglycerides from milk of several species of mammals, Lipids, vol.17, issue.6, pp.437-442, 1982.

I. Pitino, C. L. Randazzo, K. L. Cross, M. L. Parker, C. Bisignano et al.,

C. Caggia, Survival of Lactobacillus rhamnosus strains inoculated in cheese matrix during simulated human digestion, Food Microbiology, vol.31, pp.57-63, 2012.

I. Pitino, C. L. Randazzo, G. Mandalari, A. Lo-curto, R. M. Faulks et al.,

M. S. Wickham, Survival of Lactobacillus rhamnosus strains in the upper gastrointestinal tract, Food Microbiology, vol.27, pp.1121-1127, 2010.

S. Prakash, Q. Ma, and B. Bhandari, Rheological behaviour of selected commercially available baby formulas in simulated human digestive system, Food Research International, vol.64, pp.889-895, 2014.

C. S. Ranadheera, C. A. Evans, C. A. Adams, and S. K. Baines, In vitro analysis of gastrointestinal tolerance and intestinal cell adhesion of probiotics in goat's milk ice cream and yogurt, Food Research International, vol.49, pp.619-625, 2012.

L. Rinaldi, S. F. Gauthier, M. Britten, and S. L. Turgeon, In vitro gastrointestinal digestion of liquid and semi-liquid dairy matrixes, LWT -Food Science and Technology, vol.57, issue.1, pp.99-105, 2014.

F. Salaün, B. Mietton, and F. Gaucheron, Buffering capacity of dairy products, International Dairy Journal, vol.15, pp.95-109, 2005.

M. E. Sanders and M. L. Marco, Food Formats for Effective Delivery of Probiotics, The Annual Reviews of Food Science and Technology, vol.1, pp.65-85, 2009.

A. Sarkar, K. K. Goh, R. P. Singh, and H. Singh, Behaviour of an oil-in-water emulsion stabilized by ?-lactoglobulin in an in vitro gastric model, Food Hydrocolloids, vol.23, issue.6, pp.1563-1569, 2009.

M. Saxelin, A. Lassig, H. Karjalainen, S. Tynkkynen, A. Surakka et al., Persistence of probiotic strains in the gastrointestinal tract when administered as capsules, yoghurt, or cheese, International Journal of Food MIcrobiology, vol.144, pp.293-300, 2010.

M. Schlamowitz and L. U. Peterson, Studies on the Optimun pH for the Action of Pepsin on "Native" and Denatured Bovine Serum Albumin and Bovine Hemoglobin, The Journal of Biological Chemistry, vol.234, issue.12, pp.3137-3145, 1959.

I. Sumeri, S. Adamberg, R. Uusna, I. Sarand, and T. Paalme, Survival of cheese bacteria in a gastrointestinal tract simulator, International Dairy Journal, vol.25, pp.36-41, 2012.

C. Q. Sun, C. J. O´connor, and A. M. Roberton, The antimicrobial properties of milkfat after partial hydrolysis by calf pregastric lipase, Chemico-Biological Interactions, vol.140, pp.185-198, 2002.

S. L. Turgeon and L. Rioux, Food matrix impact on macronutrients nutritional properties Food Hydrocolloids, vol.25, pp.1915-1924, 2011.

P. Upreti, P. Bühlmann, and L. E. Metzger, Influence of Calcium and Phosphorus, Lactose, and Salt-to-Moisture Ratio on Cheddar Cheese Quality: pH Buffering Properties of Cheese, Journal of dairy science, vol.89, pp.938-950, 2006.

O. Uriot, W. Galia, A. A. Awussi, C. Perrin, S. Denis et al.,

Y. Roussel, Use of the dynamic gastro-intestinal model TIM to explore the survival of the yogurt bacterium Streptococcus thermophilus and the metabolic activities induced in the simulated human gut, Food Microbiology, vol.53, pp.18-29, 2016.
URL : https://hal.archives-ouvertes.fr/hal-01575589

N. References-adouard, B. Foligné, J. Dewulf, M. Bouix, D. Picque et al., In vitro characterization of the digestive stress response and immunomodulatory properties of microorganisms isolated from smear-ripened cheese, International Journal of Food MIcrobiology, vol.197, pp.98-107, 2015.

M. Albenzio, M. R. Corbo, S. U. Rehman, P. F. Fox, M. De-angelis et al., Microbiological and biochemical characteristics of Canestrato Pugliese cheese made from raw milk, pasteurized milk or by heating the curd in hot whey, International Journal of Food MIcrobiology, p.67, 2001.

M. Barác, M. Smiljanic, S. Zilic, M. Pesic, S. Stanojevic et al., Protein profiles and total antioxidant capacity of water soluble and insoluble protein fractions of white cow cheese at different stage of ripening, Mljekarstavo, vol.66, issue.3, pp.187-197, 2016.

M. Begley, C. G. Gahan, and C. Hill, The interaction between bacteria and bile, FEMS Microbiology Reviews, vol.29, pp.625-651, 2005.

B. Bogovic-matijasic, T. Obermajer, L. Lipoglavsek, T. Sernel, I. Locatelli et al.,

C. Bottesini, S. Paolella, F. Lambertini, G. Galaverna, T. Tedeschi et al.,

S. Sforza, Antioxidant capacity of water soluble extracts from Parmigiano-Reggiano cheese, Food Science and Nutrition, vol.68, issue.8, pp.963-968, 2013.

J. M. Castro, M. E. Tornadijo, J. M. Fresno, and H. Sandoval, Biocheese: A Food Probiotic Carrier, BioMed Research International, 2014.

P. L. Conway, S. L. Gorbach, and B. R. Goldin, Survival of Lactic Acid Bacteria in the Human Stomach and Adhesion to Intestinal Cells, Journal of dairy science, vol.70, issue.1, pp.1-12, 1987.

J. Choi, L. Sabikhi, A. Hassan, and S. Anand, Bioactive peptides in dairy products, International Journal of Dairy Technology, vol.65, issue.1, pp.1-12, 2012.

M. De-angelis and M. Gobbetti, Environmental stress responses in Lactobacillus: A review, Proteomics, vol.4, pp.106-122, 2004.

C. De-simone, G. Picariello, G. Mamone, P. Stiuso, A. Dicitore et al., , 2009.

, Characterisation and cytomodulatory properties of peptides from Mozzarella di Bufala Campana cheese whey, Journal of Peptide Science, vol.15, pp.251-258

M. H. El-salam and S. El-shibiny, Bioactive Peptides of Buffalo, Camel, Goat, Sheep, Mare, and Yak Milks and Milk Products, Food Reviews International, vol.29, issue.1, pp.1-23, 2012.

F. J. Espejo-carpio, C. De-gobba, A. Guadix, E. M. Guadix, and J. Otte, Angiotensin Iconverting enzyme inhibitory activity of enzymatic hydrolysates of goat milk protein fractions, International Dairy Journal, vol.32, issue.2, pp.175-183, 2013.

J. Á. Gómez-ruiz, I. López-expósito, A. Pihlanto, M. Ramos, and I. Recio, Antioxidant activity of ovine casein hydrolysates: identification of active peptides by HPLC-MS/MS, European Food Research and Technology, vol.227, issue.4, pp.1061-1067, 2008.

D. Gonzalez-de-llano, M. C. Polo, and M. Ramos, Study of Proteolysis in Liquid Chromatography Artisanal Cheeses: High Performance of Peptides, Journal of dairy science, vol.78, pp.1018-1024, 1995.

A. Gupta, B. Mann, R. Kumar, and R. B. Sangwan, Antioxidant activity of Cheddar cheeses at different stages of ripening, International Journal of Dairy Technology, vol.62, issue.3, 2009.

A. Gupta, B. Mann, R. Kumar, and R. B. Sangwan, ACE-Inhibitory Activity of Cheddar Cheeses Made with Adjunct Cultures at Different Stages of Ripening, Advances in Dairy Research, issue.1, p.1, 2013.

F. Hong, L. Ming, S. Yi, L. Zhanxia, W. Yongquan et al., The antihypertensive effect of peptides: A novel alternative to drugs? Peptides, vol.29, pp.1062-1071, 2008.

F. Ibrahim, S. Ruvio, L. Granlund, S. Salminen, M. Viitanen et al., Probiotics and immunosenescence: cheese as a carrier, FEMS Immunology and Medical Microbiology, vol.59, pp.53-59, 2010.

F. Irlinger, . Ah-yuen-in, S. Yung, A. Sarthou, C. Delbès-paus et al.,

J. M. Janda and S. L. Abbott, The Genus Hafnia: from Soup to Nuts, Clinical Microbiology Reviews, vol.19, issue.1, pp.12-18, 2006.

H. A. K?rmac?, A. A. Hayaloglu, H. B. Özer, A. F. Atasoy, and H. Türkoglud, Evolution of proteolysis in Urfa cheese made from ewe's milkby wild type starter culture systems, 2014.

, Small Ruminant Research, vol.119, pp.120-129

S. Lamothe, M. Corbeil, S. L. Turgeon, and M. Britten, Influence of cheese matrix on lipid digestion in a simulated gastro-intestinal environment. Food and Function, vol.3, pp.724-731, 2012.

C. Lay, M. Sutren, P. Lepercq, C. Juste, L. Rigottier-gois et al.,

L. Lignitto, V. Cavatorta, S. Balzan, G. Galaverna, G. Novelli et al.,

S. Segato, , 2010.

, Angiotensin-converting enzyme inhibitory activity of water-soluble extracts of Asiago d'allevo cheese, International Dairy Journal, vol.20, pp.11-17

I. Lopez-exposito and I. Recio, Protective Effect of Milk Peptides: Antibacterial and Antitumor Properties, Bioactive components of milk, vol.606, pp.271-293, 2008.

P. L. Mcsweeney, Biochemistry of cheese ripening, International Journal of Dairy Technology, vol.57, pp.127-144, 2004.
URL : https://hal.archives-ouvertes.fr/hal-00930648

P. L. Mcsweeney and P. F. Fox, Chemical methods for the characterization of proteolysis in cheese during ripening, Lait, vol.77, pp.41-76, 1997.
URL : https://hal.archives-ouvertes.fr/hal-00929515

H. Meisel, Multifunctional peptides encrypted in milk proteins, BioFactors, vol.21, pp.55-61, 2004.

S. Mills, C. Stanton, G. F. Fitzgerald, and R. P. Ross, Enhancing the stress responses of probiotics for a lifestyle from gut to product and back again, Microbial Cell Factories, vol.10, issue.1, pp.1-15, 2011.

, Lait, vol.87, pp.149-165

M. Paul and D. L. Van-hekken, Assessing antihypertensive activity in native and model Queso Fresco cheeses, Journal of dairy science, vol.94, pp.2280-2284, 2011.

A. Pihlanto, Antioxidative peptides derived from milk proteins, International Dairy Journal, vol.16, issue.11, pp.1306-1314, 2006.

I. Pitino, C. L. Randazzo, K. L. Cross, M. L. Parker, C. Bisignano et al.,

C. Caggia, Survival of Lactobacillus rhamnosus strains inoculated in cheese matrix during simulated human digestion, Food Microbiology, vol.31, pp.57-63, 2012.

S. R. Pritchard, M. Phillips, and K. Kailasapathy, Identification of bioactive peptides in commercial Cheddar cheese, Food Research International, vol.43, pp.1545-1548, 2010.

E. Ryhänen, A. Pihlanto-leppälä, and E. Pahkala, A new type of ripened, low-fat cheese with bioactive properties, International Dairy Journal, vol.11, pp.441-447, 2001.

R. A. Silva, M. S. Lima, J. B. Viana, V. S. Bezerra, V. S. Pimentel et al.,

J. L. Lima-filho, Can artisanal ''Coalho'' cheese from Northeastern Brazil be used as a functional food? Food Chemistry, vol.135, pp.1533-1538, 2012.

H. E. Spinnler and J. C. Gripon, Surface Mould-ripened Cheeses, Cheese: Chemistry, Physics and Microbiology, vol.2, pp.157-174, 2004.

C. Q. Sun, C. J. O´connor, and A. M. Roberton, The antimicrobial properties of milkfat after partial hydrolysis by calf pregastric lipase, Chemico-Biological Interactions, vol.140, pp.185-198, 2002.

M. Torres-llanez, A. González-córdova, A. Hernandez-mendoza, H. Garcia, and B. Vallejo-cordoba, Angiotensin-converting enzyme inhibitory activity in Mexican Fresco cheese, Journal of dairy science, vol.94, issue.8, pp.3794-3800, 2011.

O. Uriot, W. Galia, A. A. Awussi, C. Perrin, S. Denis et al.,

J. Vivas, D. Padilla, F. Real, J. Bravo, V. Grasso et al., Influence of environmental conditions on biofilm formation by Hafnia alvei strains, Veterinary microbiology, vol.129, pp.150-155, 2008.

W. Wang, N. Wang, Y. Zhang, Z. Cai, Q. Chen et al., A Convenient RP-HPLC Method for Assay Bioactivities of Angiotensin I-Converting Enzyme Inhibitory Peptides, Biotechnology, 2013.

L. Abadía-garcía, A. Cardador, S. T. Martín-del-campo, S. M. Arvízu, E. Castaño-tostado et al., Influence of probiotic strains added to Cottage Cheese on potentially-antioxidant peptides generation, anti-Listerial activity, and survival of probiotic microorganisms in simulated astrointestinal conditions, International Dairy Journal, vol.33, issue.2, pp.191-197, 2013.

N. Adouard, Les micro-organismes du microbiote fromager survivent-ils à la digestion et peuvent-ils avoir un effet immunomodulateur sur l'hôte ? (Docteur), 2015.

S. Agboola, S. Chen, and J. Zhao, Formation of bitter peptides during ripening of ovine milk cheese made with dierent coagulants, Le Lait, vol.84, issue.6, pp.567-578, 2004.

A. S. Ahmed, T. El-bassiony, L. M. Elmalt, and H. R. Ibrahim, Identification of potent antioxidant bioactive peptides from goat milk proteins, Food Research International, vol.74, pp.80-88, 2015.

H. ?. Alo?lu and Z. Öner, Determination of antioxidant activity of bioactive peptide 223 fractions obtained from yogurt, Journal of dairy science, vol.94, pp.5305-5314, 2011.

B. N. Ames, M. K. Shigenaga, and T. M. Hagen, Oxidants, antioxidants, and the degenerative diseases of aging, Proceedings of the National Academy of Sciences, vol.90, pp.7915-7922, 1993.

A. Baliarda, Evaluation de la reponse au stress chez les bacteries lactiques partenant aux genres Pediococcus et Tetragenococcus. Approches physiologiques et genetiques. (Docteur), 2003.

F. Barbé, S. Le-feunteun, D. Rémond, O. Ménard, J. Jardin et al.,

D. Dupont, , 2014.

M. Begley, C. G. Gahan, and C. Hill, The interaction between bacteria and bile, FEMS Microbiology Reviews, vol.29, pp.625-651, 2005.

N. C. Bertola, A. N. Califano, A. E. Bevilacqua, and N. E. Zaritzky, Effects of ripening conditions on the texture of Gouda cheese, International Journal of Food Science and Technology, vol.35, pp.207-214, 2000.

B. Bogovic-matijasic, T. Obermajer, L. Lipoglavsek, T. Sernel, I. Locatelli et al.,

H. Boke, B. Aslim, and G. Alp, The role of resistance to bile salts and acid tolerance of exopolysaccharides (EPSS) produced by yogurt starter bacteria, Archives of biological sciences, vol.62, issue.2, pp.323-328, 2010.

C. Bottesini, S. Paolella, F. Lambertini, G. Galaverna, T. Tedeschi et al.,

S. Sforza, Antioxidant capacity of water soluble extracts from Parmigiano-Reggiano cheese, Food Science and Nutrition, vol.68, issue.8, pp.963-968, 2013.

C. Bourlieu, O. Ménard, A. De-la-chevasnerie, L. Sams, F. Rousseau et al.,

J. Calbet and D. Maclean, Role of caloric content on gastric emptying in humans, The Journal of physiology, vol.498, p.553, 1997.

J. G. Caporaso, J. Kuczynski, J. Stombaugh, K. Bittinger, F. D. Bushman et al.,

J. I. Gordon, QIIME allows analysis of high-throughput community sequencing data, Nature methods, vol.7, issue.5, pp.335-336, 2010.

J. M. Castro, M. E. Tornadijo, J. M. Fresno, and H. Sandoval, Biocheese: A Food Probiotic Carrier, BioMed Research International, 2014.

P. L. Conway, S. L. Gorbach, and B. R. Goldin, Survival of Lactic Acid Bacteria in the Human Stomach and Adhesion to Intestinal Cells, Journal of dairy science, vol.70, issue.1, pp.1-12, 1987.

P. D. Cotter and C. Hill, Surviving the Acid Test: Responses of Gram-Positive Bacteria to Low pH, Microbioology and Molecular Biology Reviews, vol.67, issue.3, pp.429-453, 2003.

D. Cushman and H. Cheung, Spectrophotometric assay and properties of the angiotensinconverting enzyme of rabbit lung, Biochemical pharmacology, vol.20, issue.7, pp.1637-1648, 1971.

H. Chen, K. Muramoto, F. Yamauchi, K. Fujimoto, and K. Nokihara, Antioxidative Properties of Histidine-Containing Peptides Designed from Peptide Fragments Found in the Digests of a Soybean Protein, Journal of Agricultural and Food Chemistry, vol.46, pp.49-53, 1998.

H. Choi, C. Yang, K. Choi, and I. Bae, Characteristics of Gouda cheese supplemented with fruit liquors, Journal of Animal Science and Technology, issue.15, p.57, 2015.

J. Choi, L. Sabikhi, A. Hassan, and S. Anand, Bioactive peptides in dairy products, International Journal of Dairy Technology, vol.65, issue.1, pp.1-12, 2012.

P. Chombo-morales, M. Kirchmayr, A. Gschaedler, E. Lugo-cervantes, and S. Villanueva-rodríguez, Effects of controlling ripening conditions on the dynamics of the native microbial population of Mexican artisanal Cotija cheese assessed by, 2016.

, , vol.65, pp.1153-1161

L. A. David, C. F. Maurice, R. N. Carmody, D. B. Gootenberg, J. E. Button et al.,

M. A. Fischbach, Diet rapidly and reproducibly alters the human gut microbiome, Nature, issue.7484, pp.559-563, 2014.

M. De-angelis and M. Gobbetti, Environmental stress responses in Lactobacillus: A review, Proteomics, vol.4, pp.106-122, 2004.

C. De-simone, G. Picariello, G. Mamone, P. Stiuso, A. Dicitore et al., , 2009.

, Characterisation and cytomodulatory properties of peptides from Mozzarella di Bufala Campana cheese whey, Journal of Peptide Science, vol.15, pp.251-258

H. Devle, E. K. Ulleberg, C. F. Naess-andresen, E. Rukke, G. Vegarud et al., Reciprocal interacting effects of proteins and lipids during ex vivo digestion of bovine milk, International Dairy Journal, vol.36, issue.1, pp.6-13, 2014.

C. Dunne, L. O´mahony, L. Murphy, G. Thorton, D. Morrissey et al.,

J. K. Collins, In vitro selection criteria for probiotic bacteria of human origin: correlation with in vivo findings, The American Journal of Clinical Nutrition, vol.73, issue.2, pp.386-392, 2001.

D. Dupont, G. Mandalari, D. Molle, J. Jardin, O. Rolet-repecaud et al.,

A. R. Mackie, Food processing increases casein resistance to simulated infant digestion. Molecular Nutrition and Food Research, vol.54, pp.1677-1689, 2010.

R. C. Edgar, Search and clustering orders of magnitude faster than BLAST, 2010.

, Bioinformatics, vol.26, issue.19, pp.2460-2461

M. H. El-salam and S. El-shibiny, Bioactive Peptides of Buffalo, Camel, Goat, Sheep, Mare, and Yak Milks and Milk Products, Food Reviews International, vol.29, issue.1, pp.1-23, 2012.

O. El-galiou, S. Zantar, M. Bakkali, and A. Laglaoui, Lipolysis and Proteolysis During the Ripening of Fresh Moroccan Goats' Milk Cheese, World Journal of Dairy & Food Sciences, vol.8, pp.201-206, 2013.

M. Elli, M. L. Callegari, S. Ferrari, E. Bessi, D. Cattivelli et al.,

J. Antoine, Survival of Yogurt Bacteria in the, Human Gut. Applied and Enviromental Microbiology, vol.72, issue.7, pp.5113-5117, 2006.
URL : https://hal.archives-ouvertes.fr/hal-00294424

, bioactive peptides in reducing the risk of cardiovascular disease, The Journal of Nutritional Biochemistry, vol.19, issue.10, pp.643-654

R. J. Fitzgerald, B. A. Murray, and D. J. Walsh, Hypotensive peptides from milk proteins, The Journal of nutrition, vol.134, issue.4, pp.980-988, 2004.

R. Flores-magallón, A. A. Oliva-hernández, and J. A. Narváez-zapata, Characterization of Microbial Traits Involved with the Elaboration of the Cotija Cheese, Food Science and Biotechnology, vol.20, issue.4, pp.997-1003, 2011.

P. F. Fox and P. L. Mcsweeney, Proteolysis in cheese during ripening, Food Reviews International, vol.12, issue.4, pp.457-509, 1996.
URL : https://hal.archives-ouvertes.fr/hal-00929515

M. Gobbetti, Extra-hard varieties. Cheese: Chemistry, Physics and Microbiology, vol.2, pp.51-70, 2004.

D. Gonzalez-de-llano, M. C. Polo, and M. Ramos, Study of Proteolysis in Liquid Chromatography Artisanal Cheeses: High Performance of Peptides, Journal of dairy science, vol.78, pp.1018-1024, 1995.

J. C. Gripon, Flavour and textrure in soft cheese, Microbiology and Biochemistry of Cheese and Fermented Milk, vol.1, pp.193-203, 1997.

J. A. Guerra-martínez, J. G. Montejano, and S. T. Martín-del-campo, Evaluation of proteolytic and physicochemical changes during storage of fresh Panela cheese from, 2012.

. Queretaro, Mexico and its impact in texture, CyTA -Journal of Food, vol.10, issue.4, pp.296-305

H. Guillemin, B. Perret, D. Picque, O. Menard, and T. Cattenoz, Logiciel StoRMstomach and duodenum regulation and monitoring, 2010.

T. P. Guinee and D. J. O´callaghan, The formation of Cheese Curd, Techology of Cheesemaking, pp.260-314, 2010.

. Blackwell,

J. S. Gunn, Mechanisms of bacterial resistance and response to bile, Microbes and Infection, vol.8, pp.907-913, 2000.

A. Gupta, B. Mann, R. Kumar, and R. B. Sangwan, Antioxidant activity of Cheddar cheeses at different stages of ripening, International Journal of Dairy Technology, vol.62, issue.3, 2009.

A. Gupta, B. Mann, R. Kumar, and R. B. Sangwan, ACE-Inhibitory Activity of Cheddar Cheeses Made with Adjunct Cultures at Different Stages of Ripening, Advances in Dairy Research, issue.1, p.1, 2013.

B. Hajirostamloo, Bioactive component in milk and dairy product, World Acad Sci Eng Technol, vol.72, pp.162-166, 2010.

R. Hartmann and H. Meisel, Food-derived peptides with biological activity: from research to food applications, Current opinion in biotechnology, vol.18, issue.2, pp.163-169, 2007.

A. A. Hayaloglu and E. Y. Brechany, Influence of milk pasteurization and scalding temperature on the volatile compounds of Malatya, a farmhouse Halloumi-type cheese, 2007.
URL : https://hal.archives-ouvertes.fr/hal-00895632

, Lait, vol.87, pp.39-57

C. Hernández-morales, A. Hernández-montes, E. Aguirre-mandujano, and A. Villegas, , 2010.

. Physicochemical, textural and sensory characterisation of Mexican Añejo cheese, International Journal of Dairy Technology, vol.63, issue.4, pp.552-560

V. Hernández, A. Navarro, and M. Quirasco, Antioxidant capacity in the Cotija "Región de Origen" Cheese, the case of an artisanal cheese, Carnilac Industrial, vol.24, issue.1, pp.24-31, 2009.

V. Hernández, M. Quirasco, and B. Quintero, Un acercamiento al mundo del queso Cotija Región de Origen MC: arte y tradición de México, Culinaria, Revista Virtual Gastronómica, vol.5, pp.5-19, 2009.

J. Hnosko, S. Clark, D. S. Van-hekken, . Clark, M. Costello et al., Latin American Cheeses, The Sensory Evaluation of Dairy Products, pp.489-504, 2009.

F. Hong, L. Ming, S. Yi, L. Zhanxia, W. Yongquan et al., The antihypertensive effect of peptides: A novel alternative to drugs? Peptides, vol.29, pp.1062-1071, 2008.

R. W. Hutkins and N. L. Nannen, pH Homeostasis in Lactic Acid Bacteria, Journal of dairy science, vol.76, issue.8, pp.77573-77579, 1993.

F. Ibrahim, S. Ruvio, L. Granlund, S. Salminen, M. Viitanen et al., Probiotics and immunosenescence: cheese as a carrier, FEMS Immunology and Medical Microbiology, vol.59, pp.53-59, 2010.

R. A. Inglingstad, T. G. Devold, E. K. Eriksen, H. Holm, M. Jacobsen et al.,

F. Irlinger, . Ah-yuen-in, S. Yung, A. Sarthou, C. Delbès-paus et al.,

P. Jäkälä and H. Vapaatalo, Antihypertensive Peptides from Milk Proteins, Pharmaceuticals, vol.3, issue.1, pp.251-272, 2010.

J. M. Janda and S. L. Abbott, The Genus Hafnia: from Soup to Nuts, Clinical Microbiology Reviews, vol.19, issue.1, pp.12-18, 2006.

T. Janhoj and K. B. Qvist, The formation of Cheese Curd, Techology of Cheesemaking, pp.130-156, 2010.

M. Johnson and B. A. Law, The Origins, Development and Basic Operations of Cheesemaking Technology, Technology of CheesemakingSociety of Dairy Technology book series, vol.1, pp.68-96, 2010.

M. C. Katsiari, E. Alichanidis, L. P. Voutsinas, and I. G. Roussis, Proteolysis in reduced sodium Feta cheese made by partial substitution of NaCl by KCl, International Dairy Journal, vol.10, pp.635-646, 2000.

S. B. Kedare and R. Singh, Genesis and development of DPPH method of antioxidant assay, Journal of food science and technology, vol.48, issue.4, pp.412-422, 2011.

H. A. K?rmac?, A. A. Hayaloglu, H. B. Özer, A. F. Atasoy, and H. Türkoglud, Evolution of proteolysis in Urfa cheese made from ewe's milkby wild type starter culture systems, 2014.

, Small Ruminant Research, vol.119, pp.120-129

F. Kong and R. P. Singh, Disintegration of Solid Foods in Human Stomach, Journal of Food Science, vol.73, issue.5, 2008.

H. Korhonen, Milk-derived bioactive peptides: From science to applications, Journal of Functional Foods, vol.1, issue.2, pp.177-187, 2009.

H. Korhonen and A. Pihlanto, Food-derived Bioactive Peptides -Opportunities for Designing Future Foods, Current Pharmaceutical Design, vol.9, pp.1297-1308, 2003.

H. Korhonen and A. Pihlanto, Bioactive peptides: Production and functionality, International Dairy Journal, vol.16, pp.945-960, 2006.

P. M. Kris-etherton, K. D. Hecker, A. Bonanome, S. M. Coval, A. E. Binkoski et al., Bioactive Compounds in Foods: Their Role in the Prevention of Cardiovascular Disease and Cancer, The American Journal of Medicine, vol.113, issue.9B, pp.71-88, 2002.

C. Lacroix, P. Verret, and P. Paquin, Regional and Seasonal Variations of Nitrogen Fractions in Commingled Milk, International Dairy Journal, vol.6, pp.947-961, 1996.

S. Lamothe, M. Corbeil, S. L. Turgeon, and M. Britten, Influence of cheese matrix on lipid digestion in a simulated gastro-intestinal environment. Food and Function, vol.3, pp.724-731, 2012.

C. Lay, M. Sutren, P. Lepercq, C. Juste, L. Rigottier-gois et al.,

G. Li, Intestinal Probiotics: Interactions with Bile Salts and Reduction of Cholesterol, 2012.

L. Lignitto, V. Cavatorta, S. Balzan, G. Galaverna, G. Novelli et al.,

S. Segato, , 2010.

, Angiotensin-converting enzyme inhibitory activity of water-soluble extracts of Asiago d'allevo cheese, International Dairy Journal, vol.20, pp.11-17

I. Lopez-exposito and I. Recio, Protective Effect of Milk Peptides: Antibacterial and Antitumor Properties, Bioactive components of milk, vol.606, pp.271-293, 2008.

J. Lucey, B. Hauth, C. Gorry, and P. Fox, The acid-base buffering properties of milk, Milchwissenschaft, vol.48, issue.5, pp.268-272, 1993.

J. A. Lucey and P. F. Fox, Importance of Calcium and Phosphate in Cheese Manufacture: A Review, Journal of dairy science, vol.76, issue.6, pp.77504-77513, 1993.

Q. Lüthi-peng and Z. Puhan, Determination of protein and casein in milk by fourth derivative UV spectrophotometry, Analytica Chimica Acta, vol.393, issue.1-3, pp.227-234, 1999.

T. Mago? and S. L. Salzberg, FLASH: fast length adjustment of short reads to improve genome assemblies, Bioinformatics, vol.27, issue.21, pp.2957-2963, 2011.

O. Martínez-augustin, . Martínez-de, and E. Victoria, Proteins and peptides in enteral nutrition, Nutrición Hospitalaria, vol.21, issue.2, pp.1-14, 2006.

H. K. Mayer, C. Rockenbauer, and H. Mlcak, Evaluation of proteolysis in Parmesan cheese using electrophoresis and HPLC, Dairy Science and Technology, vol.78, issue.4, pp.425-438, 1998.
URL : https://hal.archives-ouvertes.fr/hal-00929606

M. E. Mcbee and D. B. Schauer, The Genus Hafnia, Proteobacteria: Gamma Subclass, vol.6, pp.215-218, 2006.

D. Mcdonald, M. N. Price, J. Goodrich, E. P. Nawrocki, T. Z. Desantis et al.,

, ecological and evolutionary analyses of bacteria and archaea, ISME J, vol.6, issue.3, pp.610-618

P. L. Mcsweeney, Biochemistry of cheese ripening, International Journal of Dairy Technology, vol.57, pp.127-144, 2004.
URL : https://hal.archives-ouvertes.fr/hal-00930648

P. L. Mcsweeney and P. F. Fox, Chemical methods for the characterization of proteolysis in cheese during ripening, Lait, vol.77, pp.41-76, 1997.
URL : https://hal.archives-ouvertes.fr/hal-00929515

P. L. Mcsweeney and M. J. Sousa, Biochemical pathways for the production of flavour compounds in cheeses during ripening: A review, Lait, vol.80, pp.293-324, 2000.
URL : https://hal.archives-ouvertes.fr/hal-00895408

H. Meisel, Multifunctional peptides encrypted in milk proteins, BioFactors, vol.21, pp.55-61, 2004.

H. Meisel, Biochemical Properties of Peptides Encrypted in Bovine Milk Proteins, Current medicinal chemistry, vol.12, pp.1623-1629, 2005.

H. Meisel and S. Günther, Food proteins as precursors of peptides modulating human cell activity, Food / Nahrung, vol.42, pp.175-176, 1998.

O. Ménard, T. Cattenoz, H. Guillemin, I. Souchon, A. Deglaire et al., Validation of a new in vitro dynamic system to simulate infant digestion, Food Chemistry, vol.145, pp.1039-1045, 2014.

M. Michalski, On the supposed influence of milk homogenization on the risk of CVD, diabetes and allergy, British Journal of Nutrition, vol.97, pp.598-610, 2007.

B. Mollet and I. Rowland, Functional foods: at the frontier between food and pharma, Current in Opinion and Biotechnology, vol.13, pp.483-486, 2002.

, Lait, vol.87, pp.149-165

J. Parada and J. M. Aguilera, Food Microstructure Affects the Bioavailability of Several Nutrients, Journal of Food Science, vol.72, issue.2, pp.21-32, 2007.

P. W. Parodi, Positional distribution of fatty acids in triglycerides from milk of several species of mammals, Lipids, vol.17, issue.6, pp.437-442, 1982.

M. Paul and D. L. Van-hekken, Assessing antihypertensive activity in native and model, 2011.

M. Pavia, A. J. Trujillo, B. Guamis, and V. Ferragut, Ripening control of salt-reduced Manchego-type cheeseobtained by brine vacuum-mpregnation, Food Chemistry, vol.70, pp.155-162, 2000.

L. J. Piddock, Multidrug-resistance efflux pumps, not just for resistance, Nature Reviews Microbiology, vol.4, pp.629-636, 2006.

A. Pihlanto, Antioxidative peptides derived from milk proteins, International Dairy Journal, vol.16, issue.11, pp.1306-1314, 2006.

I. Pitino, C. L. Randazzo, K. L. Cross, M. L. Parker, C. Bisignano et al.,

C. Caggia, Survival of Lactobacillus rhamnosus strains inoculated in cheese matrix during simulated human digestion, Food Microbiology, vol.31, pp.57-63, 2012.

I. Pitino, C. L. Randazzo, G. Mandalari, A. Lo-curto, R. M. Faulks et al.,

M. S. Wickham, Survival of Lactobacillus rhamnosus strains in the upper gastrointestinal tract, Food Microbiology, vol.27, pp.1121-1127, 2010.

T. Poméon, El queso Cotija, México. Un producto con marca colectiva queso "Cotija Región de origen, 2007.

A. Prakash, F. Rigelhof, and E. Miller, Antioxidant activity. Medallion laboratories analytical progress, vol.19, pp.1-4, 2001.

S. Prakash, Q. Ma, and B. Bhandari, Rheological behaviour of selected commercially available baby formulas in simulated human digestive system, Food Research International, vol.64, pp.889-895, 2014.

S. R. Pritchard, M. Phillips, and K. Kailasapathy, Identification of bioactive peptides in commercial Cheddar cheese, Food Research International, vol.43, pp.1545-1548, 2010.

C. S. Ranadheera, C. A. Evans, C. A. Adams, and S. K. Baines, In vitro analysis of 237 gastrointestinal tolerance and intestinal cell adhesion of probiotics in goat's milk ice cream and yogurt, Food Research International, vol.49, pp.619-625, 2012.

M. J. Rein, M. Renouf, C. Cruz-hernandez, L. Actis-goretta, S. K. Thakkar et al., Bioavailability of bioactive food compounds: a challenging journey to bioefficacy, British Journal of Clinical Pharmacology, vol.75, issue.3, pp.588-602, 2012.

L. Ruiz, A. Margolles, and B. Sanchez, Bile resistence mechanisms in Lactobacillus and Bifidobacterium Frontiers in Microbiology, vol.4, p.396, 2013.

E. Ryhänen, A. Pihlanto-leppälä, and E. Pahkala, A new type of ripened, low-fat cheese with bioactive properties, International Dairy Journal, vol.11, pp.441-447, 2001.

M. Saarela, G. Mogensen, R. Fonden, J. Matto, and T. Mattila-sandholm, Probiotic bacteria: safety, functional and technological properties, Journal of Biotechnology, vol.84, pp.197-215, 2000.

G. Sachs, D. L. Weeks, Y. Wen, E. A. Marcus, and D. R. Scott, Acid Acclimation by Helicobacter pylori, vol.20, pp.429-438, 2005.

T. Saito, T. Nakamura, H. Kitazawa, Y. Kawai, and T. Itoh, Isolation and Structural Analysis of Antihypertensive Peptides That Exist Naturally in Gouda Cheese, Journal of dairy science, vol.83, issue.7, pp.1434-1440, 2000.

F. Salaün, B. Mietton, and F. Gaucheron, Buffering capacity of dairy products, International Dairy Journal, vol.15, pp.95-109, 2005.

M. E. Sanders and M. L. Marco, Food Formats for Effective Delivery of Probiotics, The Annual Reviews of Food Science and Technology, vol.1, pp.65-85, 2009.

S. Hernandez and H. , Red Regional de Microqueserías Artesanales con Leche de Cabra Veracruz: Comite Nacional Sistema Producto Caprinos, 2011.

W. Scholz, Elaboración de quesos de oveja y de cabra, p.145, 1997.

R. A. Silva, M. S. Lima, J. B. Viana, V. S. Bezerra, V. S. Pimentel et al.,

J. L. Lima-filho, Can artisanal ''Coalho'' cheese from Northeastern Brazil be used as a functional food? Food Chemistry, vol.135, pp.1533-1538, 2012.

H. E. Spinnler and J. C. Gripon, Surface Mould-ripened Cheeses, Cheese: Chemistry, Physics and Microbiology, vol.2, pp.157-174, 2004.

I. Sumeri, S. Adamberg, R. Uusna, I. Sarand, and T. Paalme, Survival of cheese bacteria in a gastrointestinal tract simulator, International Dairy Journal, vol.25, pp.36-41, 2012.

C. Q. Sun, C. J. O´connor, and A. M. Roberton, The antimicrobial properties of milkfat after partial hydrolysis by calf pregastric lipase, Chemico-Biological Interactions, vol.140, pp.185-198, 2002.

J. Sun, Z. Deng, and A. Yan, Bacterial multidrug efflux pumps: Mechanisms, physiology and pharmacological exploitations, Biochemical and Biophysical Research Communications, vol.453, pp.254-267, 2014.

M. L. Timón, V. Parra, J. Otte, J. M. Broncano, and M. J. Petrón, Identification of radical scavenging peptides (<3 kDa) from Burgos-type cheese, LWT -Food Science and Technology, vol.57, issue.1, pp.359-365, 2014.

S. L. Turgeon and L. Rioux, Food matrix impact on macronutrients nutritional properties Food Hydrocolloids, vol.25, pp.1915-1924, 2011.

O. Uriot, W. Galia, A. A. Awussi, C. Perrin, S. Denis et al.,

V. Vermeirssen, J. Van-camp, and W. Verstraete, Bioavailability of angiotensin I converting enzyme inhibitory peptides, British Journal of Nutrition, vol.92, pp.357-366, 2004.

J. Vivas, D. Padilla, F. Real, J. Bravo, V. Grasso et al., Influence of environmental conditions on biofilm formation by Hafnia alvei strains, Veterinary microbiology, vol.129, pp.150-155, 2008.

D. D. Voigt, F. Chevalier, M. C. Qian, and A. L. Kelly, Effect of high-pressure treatment on microbiology, proteolysis, lipolysis and levels of flavour compounds in mature blueveined cheese, Innovative Food Science & Emerging Technologies, vol.11, issue.1, pp.68-77, 2010.
URL : https://hal.archives-ouvertes.fr/hal-02502718

Q. Wang, G. M. Garrity, J. M. Tiedje, and J. R. Cole, Naïve Bayesian Classifier for Rapid Assignment of rRNA Sequences into the New Bacterial Taxonomy, Applied and Environmental Microbiology, vol.73, issue.16, pp.5261-5267, 2007.

W. Wang, N. Wang, Y. Zhang, Z. Cai, Q. Chen et al., A Convenient RP-HPLC Method for Assay Bioactivities of Angiotensin I-Converting Enzyme Inhibitory Peptides, Biotechnology, 2013.

E. Whittier, Buffer intensities of milk and milk constituents I. The buffer action of casein in milk, Journal of Biological Chemistry, vol.83, issue.1, pp.79-88, 1929.

&. Who and . Fao, Diet, Nutrition and The prevention of chronic diseases, p.160, 2003.

, UMR 782 -Génie et Microbiologie des Procédés Alimentaires Bâtiment CBAI