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Contribution à l’exploitation de la modélisation musculosquelettique personnalisée du rachis cervical inférieur dans un contexte clinique

Abstract : Neck pain is a leading cause of invalidity and the use of surgery to treat it has been on a rising trend. Numerical modelling has and can still contribute to a better understanding of degeneration and complication mechanisms. However, implementing these advances in a clinical setting can be challenging as they can lack personalization and often require experimental measurements. Thus, the aim of this PhD thesis is to contribute to the development of subject-specific lower cervical spine models as a tool for clinical evaluation. The first part is an analysis of the gravitational loading on the cervical spine, quantifying in biomechanical terms the postural changes associated with aging and following surgery. By adapting a previous model, the second part focuses on the quantification of spinal and muscular loadings for patients before and after surgery. Additionally, though MRI segmentation for personalised muscles is required to quantify evolutions of loading during patient follow-up, it appears spinal loading can be estimated using stereoradiographs exclusively. The third part deals with the reduction of a subject-specific finite-element model using beam elements. Computation time was cut by 95 %, making it more suitable for use in clinical routine and facilitating further development to personalize its loading conditions. Using medical imaging exclusively, the works carried out over the course of this PhD contribute to the implementation of these subject-specific cervical spine modelling tools in clinical practice for a more widespread application and thus the identification of clinically and biomechanically relevant parameters to improve prevention of degeneration and surgical complications.
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https://pastel.archives-ouvertes.fr/tel-03639215
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Submitted on : Tuesday, April 12, 2022 - 4:33:11 PM
Last modification on : Friday, August 5, 2022 - 2:54:01 PM
Long-term archiving on: : Wednesday, July 13, 2022 - 7:25:01 PM

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  • HAL Id : tel-03639215, version 1

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Christophe Muth-Seng. Contribution à l’exploitation de la modélisation musculosquelettique personnalisée du rachis cervical inférieur dans un contexte clinique. Biomécanique [physics.med-ph]. HESAM Université, 2022. Français. ⟨NNT : 2022HESAE029⟩. ⟨tel-03639215⟩

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